The instructions that make us who we are translate into a diverse array of complex and highly regulated processes that occur precisely and on time in every single cell. Mistakes in these processes can lead to disease. Scientists at the Max Perutz Labs study fundamental cellular and developmental processes at a mechanistic level.
Genetic information is encoded in genes, embedded in chromatin, and organized in chromosomes. Its implementation is dynamically regulated at different levels from DNA to RNA. At the Max Perutz Labs, scientists focus on fundamental processes of inheritance, nuclear architecture, genome organization, and RNA biology from bacteria to humans.
Malfunctions in our defense systems account for more than 85% of all human deaths. Max Perutz Labs scientists dissect the molecular mechanisms underlying the regulation of immune tolerance, signaling pathways in sterile and pathogenic inflammation, including cancer, as well as the principal mechanisms of immune surveillance in healthy, autoimmune, and infectious disease settings.
Biological processes are driven by the coordinated interaction of molecules within cells and tissues. The Max Perutz Labs studies how structure is related to function, the dynamics and energetics of the macromolecules that are at the heart of these processes, and the networks in which they operate. We aim to elucidate the mechanisms that shape our normal physiology and rationalize the role of aberrant macromolecules in disease.
Starting in April 2024
Erinc Hallacli
Deciphering molecular phenotypes in neurodegenerative diseases
From chromosome folding by loop extrusion to anti-plasmid nucleases in bacteria
11:00 - 12:00
IMBA/GMI Lecture HallIdentifying and exploiting cell-state dependent metabolic programs
11:00 - 12:00 IMP Lecture HallMind matters. VBC mental health awareness
13:30 - 14:30 IMP Lecture HallChromosomes as Mechanical Objects: from E.coli to Meiosis to Mammalian cells
11:00 - 12:00 IMBA/GMI Lecture HallConvergent evolution of CO2-fixing liquid-liquid phase separation
11:30 - 12:30 GMI Orange Seminar RoomViral envelope engineering for cell type specific delivery
16:00 - 17:00 IMP Seminar Room 1.014/16New ways of leading: inclusive leadership and revising academic hierarchies
14:15 - 15:15 IMP Lecture HallTitle to be announced
14:00 - 15:00 Lecture Hall AandB, VBC5Decoding Molecular Plasticity in the Dark Proteome of the Nuclear Pore Complex
11:00 - 12:00 IMBA/GMI Lecture HallNeurodiversity in academia
14:00 - 15:00 IMP Lecture HallGene expression dynamics during the awakening of the zygotic genome
11:00 - 12:00 IMBA/GMI Lecture HallTitle to be announced
11:00 - 12:00
