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Centrioles are cytoplasmic structures whose distinguishing feature is an outer wall composed of a nine-fold symmetric array of stabilized microtubules. Centrioles perform two important functions in eukaryotic cells: 1) they form centrosomes that organize the microtubule cytoskeleton and contribute to cell division, and 2) they form cilia, cellular projections that perform critical sensory and motile functions. Reflecting their multiple roles in development and tissue homeostasis, centrosome and cilia abnormalities have been linked to cancer as well as developmental and adult disorders including ciliopathies, dwarfism and microcephaly. Work in my lab seeks to understand the fundamental and conserved molecular mechanisms underlying centriole assembly and their function in centrosome and cilium biogenesis.
In our lab we are using a combination of biochemical, cell biological and genetic approaches in the nematode C. elegans and the fruit fly D. melanogaster to investigate the fundamental and conserved molecular mechanisms underlying centriole assembly and function. In previous work we have used the C. elegans early embryo to define the molecular requirements for centriole assembly. The six-protein molecular pathway we identified has since been found to be conserved from ciliates to vertebrates, and is thought to form the core of the centriole assembly machinery in all eukaryotes. Current research builds on this foundation, seeking to answer three main questions: 1) How do centrioles assemble, and what are the molecular mechanisms that underlie their remarkable stability; 2) how do centrioles recruit pericentriolar material to form centrosomes and what is the molecular nature of this material; and 3) how do centrioles form cilia, focusing on the early events in ciliogenesis.
Following undergraduate studies at the University of Cambridge, a PhD at the Wellcome Centre for Cell Biology in Edinburgh and post-doctoral work at the Ludwig Insitute for Cancer Research in San Diego, Alex became a Junior Group Leader at the Max Perutz Labs in 2010 and in 2015 Associate Professor at the University of Vienna.
One of the main functions of centrioles is to serve as focal points for the recruitment of microtubule-organizing pericentriolar material (PCM). We previously showed that the PCM scaffold in C. elegans expands isotropically by incorporation of additional subunits throughout its volume (Laos et al., Curr Biol 2015). Thus, there is no privileged role for centrioles as docking sites for PCM assembly. However, this did not exclude an indirect, signaling role. To directly test centriole involvement we recently performed targeted laser ablation of centrioles at the onset of mitosis (Cabral, Laos et al., Dev Cell 2019). Unexpectedly, we found centrioles to be absolutely required for further PCM recruitment. Additionally, centrioles were required for centrosome structural integrity though not for maintenance of the PCM polymer per se. Thus, centrioles are certainly critical players throughout mitosis.
The other main function of centrioles, conserved in all species that possess them, is as basal bodies templating the formation of cilia. Ciliogenesis involves the docking of basal bodies to the plasma membrane and assembly of an elaborate gating structure, known as the transition zone, immediately distal to the basal body. Finally, the microtubule-based axoneme that serves the backbone of the cilium forms by direct extension of centriolar microtubules. Unusually, in C. elegans ciliated neurons, the basal body does not persist at the ciliary base, but degenerates during neuronal differentiation. Using a combination of light microscopy and electron tomography we showed that centrioles degenerate remarkably early in ciliogenesis, prior to expansion of the ciliary transition zone and axoneme elongation (Serwas et al., J Cell Biol 2017). Unlike in the case of centrosome assembly, centrioles are therefore required only for cilium initiation, but not directly involved in later steps of maturation and maintenance.
Centrioles are well known for the elaborate nine-fold symmetric architecture of their microtubule-based wall, which is essentially invariant from cell to cell and stably maintained over many generations and potentially the lifetime of the animal with no exchange of subunits with the surrounding cytoplasm. While considerable progress has been made in deciphering the molecular mechanisms underlying centriole assembly, how centrioles maintain their remarkable structural stability is not well understood. We recently identified the highly conserved centriolar protein Cep97 as a critical player in centriole stability and cilium assembly in Drosophila melanogaster (Dobbelaere et al, Curr Biol 2020). Cep97 stably binds mature centrioles and inhibits their dynamics. Loss of Cep97 results in an uncapping of centrioles and consequently shrinkage or elongation depending on cytoplasmic conditions.
A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans
Jeroen Dobbelaere, Tiffany Y Su, Balazs Erdi, Alexander Schleiffer, Alexander Dammermann
An acentriolar centrosome at the C. elegans ciliary base.
Garbrecht, Joachim; Laos, Triin; Holzer, Elisabeth; Dillinger, Margarita; Dammermann, Alexander
Cep97 Is Required for Centriole Structural Integrity and Cilia Formation in Drosophila.
Dobbelaere, Jeroen; Schmidt Cernohorska, Marketa; Huranova, Martina; Slade, Dea; Dammermann, Alexander
We are looking for talented, ambitious scientists at various levels. Postdoc, PhD and Master student positions are currently available. Please contact Alexander and include a summary of previous research interests, a statement with your motivation to join the team, and the names of potential referees in your application.
The Group Dammermann participates in in the special Doctoral Program 'Chromosome Dynamics' reviewed and funded by the Austrian Research Fund FWF.
The Group Dammermann is an associate member of the Special Research Area (SFB) "Chromosome Dynamics - Unraveling the function of chromosomal domains" funded by the Austrian Science Fund FWF.
Project title: "Molecular Analysis of Centriole Assembly and Function"
Project title: "Identification and characterization of novel ciliogenesis factors"
Project title: "Molecular Analysis of Interphase Centrosomal Structures"
Project title: "Developing CryoEM/CLEM methods for analysis of cellular architecture"
Clementine Schouteden 2010, Gabriela Cabral 2012, Jeroen Dobbelaere 2013, Cornelia Rumpf-Kienzl 2015, Tiffany Su 2016, Claudia Pachinger 2019, Marketa Schmidt Cernohorska 2020
Molecular Environmental Science: Linking carbon and metal biogeochemical cycles from molecular to landscape scales
Date: 2024-11-21, Time: 12:00:00, Speaker: Sharon Bone, Location: Zoom, Type: CeMESS Lecture Series, Institute: Stanford University, Host: Stephan Krämer
Structures and mechanisms of prokaryotic genome defence systems
Date: 2024-11-21, Time: 11:00:00, Speaker: Martin Jinek, Location: Zoom, Type: VBC Regular Seminar, Institute: University of Zurich, Host: Irma Querques
Exploring Light and Carbon Dynamics in the Green Microalga Chlamydomonas reinhardtii
Date: 2024-11-22, Time: 11:30:00, Speaker: Dimitris Petroutsos, Location: IMBA/GMI Lecture Hall, Type: GMI Seminar, Institute: Uppsala University, Host: Silvia Ramundo
Monday Seminar (Internal)
Date: 2024-11-25, Time: 12:30:00, Speaker: BOREIKAITE Vytaute (Plaschka)SRINIVASAN Navaneeth (Peters)DODOMANI Ananya (Campbell), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Accessing the Nanoscale with Light
Date: 2024-11-28, Time: 14:00:00, Speaker: Francisco Balzarotti, Location: VBC5, Lecture hall B/Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: IMP, Host: Kristina Djinovic-Carugo
Understanding starch granule biosynthesis in plants using insights from natural variation
Date: 2024-11-29, Time: 11:45:00, Speaker: David Seung, Location: IMBA/GMI Lecture Hall, Type: GMI Seminar, Institute: John Innes Centre, Norwich, Host: Yan Ma
Exploring the cell biology that enables efficient photosynthesis in C4 plants
Date: 2024-11-29, Time: 11:00:00, Speaker: Tina Schreier, Location: IMBA/GMI Lecture Hall, Type: GMI Seminar, Institute: University of Oxford, Host: Yan Ma
Monday Seminar (Internal)
Date: 2024-12-02, Time: 12:30:00, Speaker: SOMMER Theresa (Rivron)KRACHT Laura (Knoblich)MAIR Zahar (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Photomimetism for Marine Photosymbioses in Captivity: Simulating Tidal Cycles with Light
Date: 2024-12-03, Time: 13:15:00, Speaker: Xavier Bailly, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Station Biologique de Roscoff, Host: Uli Technau
Sense and Sensibility - Regulation of innate immune sensors
Date: 2024-12-04, Time: 14:00:00, Speaker: Konstantin Sparrer, Location: IMP Lecture Hall, Type: Impromptu Seminar, Institute: Universitätsklinikum Ulm, Host: Moritz Gaidt
The dynamic chaperone network in the endoplasmatic reticulum
Date: 2024-12-05, Time: 14:00:00, Speaker: Sebastian Hiller, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Biozentrum Basel, Host: Elif Karagöz
Microbial necromass in soil: its impact on soil properties and the fate of compounds and chemicals
Date: 2024-12-05, Time: 12:00:00, Speaker: Matthias Kästner, Location: UBB - Lecture Hall 2 & Zoom, Type: CeMESS Lecture Series, Institute: Helmholtz-Centre for Environmental Research, Host: Christina Kaiser
Biophysical and cellular analysis of mitotic human chromosomes
Date: 2024-12-05, Time: 11:00:00, Speaker: Ian Hickson, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Joao Matos
Monday Seminar (Internal)
Date: 2024-12-09, Time: 12:30:00, Speaker: BREHM Martin (Falk)PLATZER Sebastian (Hein)RAFANEL Baptiste (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Studying stem cells and regeneration across the tree of life using single cell transcriptomics
Date: 2024-12-10, Time: 13:15:00, Speaker: Jordi Solana, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: University of Exeter, Host: Tim Wollesen
Consequences (and causes) of mitotic checkpoint dysfunction
Date: 2024-12-10, Time: 11:30:00, Speaker: Gerben Vader, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: Cancer Center Amsterdam, Host: Christopher Campbell
Title to be announced
Date: 2024-12-12, Time: 14:00:00, Speaker: Shotaro Otsuka, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Max Perutz Labs, Host: Kristina Djinovic-Carugo
Cryo-EM structures provide new insights into DNA repair
Date: 2024-12-12, Time: 11:00:00, Speaker: Stephen West, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: The Francis Crick Institute, Host: Joao Matos
Sex chromosome, symbiosis, and CO2-concentrating mechanism: the secret life of hornworts
Date: 2024-12-13, Time: 11:30:00, Speaker: Fay-Wie Li, Location: GMI Orange Seminar Room, Type: GMI Seminar, Institute: Cornell University/Boyce Thompon Institute, Host: Fred Berger
Monday Seminar (Internal)
Date: 2024-12-16, Time: 12:30:00, Speaker: DAHAN Tal (Nordborg)CHUGUNOVA Anastasia (Pauli)VON WIREN Julius (Kovarik), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Mining Immunological Memory from Previous Generations
Date: 2024-12-17, Time: 13:15:00, Speaker: Matthias R. Schaefer, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Medical University of Vienna, Host: Silvia Bulgheresi
Title to be announced
Date: 2025-01-09, Time: 14:00:00, Speaker: Sergi Padilla-Parra, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: King's College London, Host: Thomas Juffmann
Cancer aneuploidy: From selection pressures to cellular vulnerabilities
Date: 2025-01-09, Time: 11:00:00, Speaker: Uri Ben-David, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Tel Aviv University, Host: Anna Obenauf
Monday Seminar (Internal)
Date: 2025-01-13, Time: 12:30:00, Speaker: KRASNOVID Filipp (Mari-Ordonez)ROTHE Patricia (Plaschka)KROGULL Daniel (Burga), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2025-01-16, Time: 11:00:00, Speaker: Stan Brouns, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Delft University of Technology, Host: Irma Querques
Monday Seminar (Internal)
Date: 2025-01-20, Time: 12:30:00, Speaker: VICIC Ziga (Jachowicz)GRÜNEWALD Jakob (Obenauf)MANOLOVA Toni (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2025-01-23, Time: 14:00:00, Speaker: Gasper Tkacik, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: ISTA, Host: Bojan Zagrovic
Title to be announced
Date: 2025-01-23, Time: 11:00:00, Speaker: Anais Cario, Location: UBB - Lecture Hall 2 & Zoom, Type: DOME Lecture Series, Institute: French National Centre for Scientific Research, Host: Hayk Palabikyan
Title to be announced
Date: 2025-01-23, Time: 11:00:00, Speaker: Anne Bertolotti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MCR Laboratory of Molecular Biology, Host: Egon Ogris
Title to be announced
Date: 2025-01-26, Time: 10:00:00, Speaker: Ori Avinoam, Location: IMBA/GMI Lecture Hall, Type: IMP Impromptu Seminar, Institute: Weizmann Institute, Host: Andi Pauli
Monday Seminar (Internal)
Date: 2025-01-27, Time: 12:30:00, Speaker: WILLIAMS Thomas (Clausen)SCARAMUZZA Federico (Tessmar)WALTER Mateusz (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Decidualisation of human endometrium: from evolutionary insights to novel mechanisms of disease
Date: 2025-01-28, Time: 13:15:00, Speaker: Jan Brosens, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: University of Warwick, Host: Mihaela Pavlicev
Title to be announced
Date: 2025-01-29, Time: 11:00:00, Speaker: Jan Brosens, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: University of Warwick, Host: Nicolas Rivron
Title to be announced
Date: 2025-01-30, Time: 14:00:00, Speaker: Marcus Taylor, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Max Planck Institute for Infection Biology, Berlin, Host: Ivan Yudushkin
Reactive Tracers in Chemical Substances: Compound-specific Isotope Analysis to Characterize Transformation of Organic Compounds
Date: 2025-01-30, Time: 12:00:00, Speaker: Martin Elsner, Location: Zoom, Type: CeMESS Lecture Series, Institute: Technical University of Munich, Host: Thilo Hofmann
Title to be announced
Date: 2025-01-30, Time: 11:00:00, Speaker: Maria-Elena Torres-Padilla, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Ludwig-Maximilians-University Munich, Host: Julius Brennecke
Monday Seminar (Internal)
Date: 2025-02-03, Time: 12:30:00, Speaker: CRUZ Joseph (Gerlich)GHEORGHITA Andreea (Clausen)GALUSKA Philipp (Djinovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2025-02-04, Time: 11:00:00, Speaker: Dominic Gruen, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: University of Würzburg, Host: Alex Stark
Ectomycorrhizal fungi as drivers of forest ecosystem processes
Date: 2025-02-06, Time: 12:00:00, Speaker: Filipa Coxx, Location: UBB - Lecture Hall 2 & Zoom, Type: CeMESS Lecture Series, Institute: University of Manchester, Host: Mark Anthony
Title to be announced
Date: 2025-02-06, Time: 11:00:00, Speaker: Thibaut Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institut Pasteur, University Paris-Cite, Host: Fred Berger
Monday Seminar (Internal)
Date: 2025-02-10, Time: 12:30:00, Speaker: GRIGOREVA Elizaveta (Nordborg)KOHOUTKOVA Eliska (Clausen)STEINACKER Thomas (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-02-13, Time: 11:00:00, Speaker: Jeff Boeke, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: NYU Langdone Health, Host: Fred Berger
Monday Seminar (Internal)
Date: 2025-02-17, Time: 12:30:00, Speaker: RAFFL Gerald (Ameres)VULIN Milica (Obenauf)FISCHER Andre (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-02-20, Time: 11:00:00, Speaker: Gaia Novarino, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: ISTA, Host: Dea Slade
Monday Seminar (Internal)
Date: 2025-02-24, Time: 12:30:00, Speaker: BAYERL Jonas (Zuber)ZABOLOCKI Michael (Knoblich)EDER Stephanie (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-02-27, Time: 11:00:00, Speaker: Cedric Feschotte, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Cornell University, Host: Joanna Jachowicz
Monday Seminar (Internal)
Date: 2025-03-03, Time: 12:30:00, Speaker: KROETENHEERDT Eva (Leonard)RÖHSNER Josef (Pauli)RIABOV Daria (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-10, Time: 12:30:00, Speaker: CHO Chung Hyun (Berger)SEIDL Carina (Tanaka)MIGOTTI Mario (Konrat), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
SY-Stem
Date: 2025-03-12, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2025-03-17, Time: 12:30:00, Speaker: CHEN Shenzhi (Stark)BINDL Michael (Leeb)JÄGER Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Unravelling the inner secrets of cells with live-cell super-resolution microscopy
Date: 2025-03-19, Time: 10:00:00, Speaker: Francesca Bottanelli, Location: Lecture Hall A, VBC 5, Type: Impromptu Seminar, Institute: Freie Universität Berlin, Host: Jonas Ries
Title to be announced
Date: 2025-03-20, Time: 11:00:00, Speaker: Geert Kops, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Joao Matos
Monday Seminar (Internal)
Date: 2025-03-24, Time: 12:30:00, Speaker: MAYA Juan (Balzarotti)DOSA Anna (Clausen)KOBER Julia (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-03-27, Time: 11:00:00, Speaker: Martin Beck, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Biophysics, Host: Alwin Köhler
Monday Seminar (Internal)
Date: 2025-03-31, Time: 12:30:00, Speaker: HOLZER Elisabeth (Martens)THEMANN Jan (Knoblich)GROSS Angelina (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-04-03, Time: 11:00:00, Speaker: Rotem Sorek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute, Host: Sebastian Falk
Monday Seminar (Internal)
Date: 2025-04-07, Time: 12:30:00, Speaker: GROH Roan (Dagdas)CHAO Victor (Huis)KHANDEKAR Ameya (Ellis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
"Tiles of Life" Symposium
Date: 2025-04-10, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall , Type: Symposium, Institute: None, Host: SMICH community
Tiles of Life - Student Symposium
The symposium will explore the intricate "tiles" that form the vast and diverse fields of molecular biology and aims to foster discussions and inspire collaborations by bringing the “tiles of life” together. The program includes several talks by esteemed and international speakers sharing their latest findings to link the molecular mosaic of the cell - from structures to organisms. Additionally, we will highlight the research of the SMICH community on campus by complementing the program with student talks.
Monday Seminar (Internal)
Date: 2025-04-14, Time: 12:30:00, Speaker: OKUN Anastasia (Karagöz)COLLISON Robert (Ramundo)WELZL Paul (Balzarotti/Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-04-24, Time: 11:00:00, Speaker: Maria Cristina Gambetta, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lausanne, Host: Anton Goloborodko
Monday Seminar (Internal)
Date: 2025-04-28, Time: 12:30:00, Speaker: SUWITA Johannes (Pauli)GRABARCZYK Daniel (Clausen)PANDA Aswini (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-05, Time: 12:30:00, Speaker: KIM Olena (Knoblich)JOB Nikhil (Dolan)ADELMANN Leonie (Raible), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Microsymposium on RNA Biology'
Date: 2025-05-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
EMBO meeting on RNA meets Protein decay
Date: 2025-05-11, Time: 14:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2025-05-12, Time: 12:30:00, Speaker: SCIBISZ Grzegorz (Karagöz)VAN GENDEREN Emiel (Rivron)BOZKURT Miray (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-05-15, Time: 11:00:00, Speaker: Chuna Ram Choudhary, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Alex Stark
Monday Seminar (Internal)
Date: 2025-05-19, Time: 12:30:00, Speaker: POTTENDORFER Elisabeth (Obenauf)WALLNER Eva-Sophie (Dolan)BECKER Moritz (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-05-22, Time: 11:00:00, Speaker: Manuel Leonetti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: CZ Biohub San Francisco, Host: Elif Karagöz
Monday Seminar (Internal)
Date: 2025-05-26, Time: 12:30:00, Speaker: DIMITROVA Polina (Van der Veeken)STRAVS Ana (Knoblich)SCHÖNLEIN Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-02, Time: 12:30:00, Speaker: SABATH Kevin (Plaschka/Stark)MANCHENO JUNCOSA Estela (Mendjan)HORENKAMP Simone (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-06-12, Time: 11:00:00, Speaker: Stefan Mundlos, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Molecular Genetics, Host: Julius Brennecke
Monday Seminar (Internal)
Date: 2025-06-16, Time: 12:30:00, Speaker: BERGER Sonja (Goloborodko)KOWALD Saskia (Gaidt)KAPRAL Thomas (Zagrovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-06-18, Time: 11:00:00, Speaker: Nikhil Joshi, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Yale University, Host: Joris Van der Veeken
Monday Seminar (Internal)
Date: 2025-06-23, Time: 12:30:00, Speaker: BUCHERON Chloe (Menche)KRUMWIEDE Luisa (Gaidt)PACHANO Tomas (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-30, Time: 12:30:00, Speaker: SCHINDLER Lukas (Schlögelhofer)MANDLBURGER Nikolaus (Stark)OTTO Magdalena (Leonard), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-07-03, Time: 11:00:00, Speaker: Matthias Mann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max-Planck Institute of Biochemistry, Host: Marco Hein
Monday Seminar (Internal)
Date: 2025-07-07, Time: 12:30:00, Speaker: TRUS Palina (Peters)KOBAKHIDZE George (Dong)KONGSTED Thea (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-07-10, Time: 11:00:00, Speaker: Simon Alberti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: TU Dresden, Host: Erinc Hallacli
Monday Seminar (Internal)
Date: 2025-07-14, Time: 12:30:00, Speaker: RUSCH Emma (Golobordko)VELIKOV Daniel (Matos)VOGEL Alexander (Clausen/Yudushkin), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-07-17, Time: 11:00:00, Speaker: Vishva Dixit, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Genentech, Host: Moritz Gaidt
Monday Seminar (Internal)
Date: 2025-07-21, Time: 12:30:00, Speaker: ANGELOPOULOU Eleni (Ellis)SCHAFFER Petra (Grade)RAMIREZ America (Köhler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-28, Time: 12:30:00, Speaker: DIMITRIADI Anna (Mendjan)LEITNER Moritz (Martinez)GAO Peng (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-04, Time: 12:30:00, Speaker: LI Wenxin (Zimmer)FISCHER Felix (Zagrovic)ABESAMIS Kim Ivan (Dong), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-11, Time: 12:30:00, Speaker: KLEIFELD Justus (Urban)MCATEER Tara (Pinheiro)BHATTACHARYA Mrinnanda (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-18, Time: 12:30:00, Speaker: BELL Lillie (Clausen)MIHAILOVIC Milica (Karagöz)GUYNES Keroshini (Jachowicz), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-25, Time: 12:30:00, Speaker: BOHL VIALLEFONT Gregoire (Nordborg)MARCHIORI Elisa (Van der Veeken)JAHNEL Stefan (Mendjan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-01, Time: 12:30:00, Speaker: KIRCHGATTERER Paul (Gaidt)ACHLEITNER Sonja (Martens)KAYA Oguzhan (Knoblich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-08, Time: 12:30:00, Speaker: HUTH Michelle (Leeb)RADHAKRISHNA PILLAI Balashankar (Brennecke)REN Kaike (Otsuka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-15, Time: 12:30:00, Speaker: GONZALEZ ALVARADO Maria Nazareth (Grade)KASHKO Nataliia (Matos)OBERHUEMER Michael (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-09-18, Time: 11:00:00, Speaker: Katja Wassmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institute Jacques Monod, Host: Joao Matos, Peter Schlögelhofer
Monday Seminar (Internal)
Date: 2025-09-22, Time: 12:30:00, Speaker: KONSTANTINOU Andri (Obenauf)HARTMANN Felix (Matos)JENTOFT Ida (Pauli), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-09-25, Time: 11:00:00, Speaker: Fabian Theis, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Computational Health Center, Helmholtz Munich, Host: Alex Stark
Monday Seminar (Internal)
Date: 2025-09-29, Time: 12:30:00, Speaker: PAVLOVA Anzhela (Matos)SHARMA Sanskriti (Ellis)VETRANO Pamela (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-10-06, Time: 12:30:00, Speaker: WIGHARD Sara Sylvia (Burga)PRLESI Ines (Gerlich)BECHT Nanette (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-10-09, Time: 11:00:00, Speaker: Alexander van Oudenaarden, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Elly Tanaka
Monday Seminar (Internal)
Date: 2025-10-13, Time: 12:30:00, Speaker: PIECH Lucas (Leonard)NABIH MOSTAFA Amena (Pauli)GREMMELMAIER Constanze (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-10-16, Time: 11:00:00, Speaker: Anne Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Stanford University, Host: Andrea Pauli
Monday Seminar (Internal)
Date: 2025-10-20, Time: 12:30:00, Speaker: KYPRIANOU Christos (Rivron)MOYSIADOU Sofia (Obenauf)GALLAGE CHANUKA POSHITHA Fernando (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-10-23, Time: 11:00:00, Speaker: Aydan Bulut-Karslioglu, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MPI Berlin, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
Date: 2025-10-27, Time: 12:30:00, Speaker: LAROVENKO Svetlana (Brennecke)HIDAKA Takuya (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-10-30, Time: 11:00:00, Speaker: Kresten Lindorff-Larssen, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: David Haselbach
Monday Seminar (Internal)
Date: 2025-11-03, Time: 12:30:00, Speaker: DIAS Ana Beatriz (Slade)VALERI Erika (Gaidt)CHATZIANGELOU Myrto (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-11-10, Time: 12:30:00, Speaker: FRASZ Lisa-Maria (Obenauf)MYLARSHCHIKOV Dmitry (Gerlich)SAHA Sayantan (Huis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-11-13, Time: 11:00:00, Speaker: Jamie Hackett, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: EMBL Rome, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
Date: 2025-11-17, Time: 12:30:00, Speaker: PITASI Mattia (Leeb)FORBES Rebecca (Görke)MATURI Samuele (Grade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
To be annouced
Date: 2025-11-20, Time: 11:00:00, Speaker: Noam Stern-Ginossar, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute of Science, Host: Marco Hein
Monday Seminar (Internal)
Date: 2025-11-24, Time: 12:30:00, Speaker: HEINZL Monika (Stark)MARTZIOS Panagiotis (Huis)BASTOS VENTURA Guilherme (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-12-01, Time: 12:30:00, Speaker: JONASSON Mattias (Bücker)KNAUDT Hannah (Haselbach), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-12-15, Time: 12:30:00, Speaker: BERKUN Kathleen (Hallacli)GRAF Max (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-01-12, Time: 12:30:00, Speaker: BOHAUMILITZKY Lena (Pinheiro)SPEICHERT Katarzyna (Martens)NG Hing Pan (Ma), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-01-19, Time: 12:30:00, Speaker: FARAWAY Rupert (Plaschka)ETHIER Elizabeth (Hallacli)RAINA Shiviya (Dammermann), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-01-26, Time: 12:30:00, Speaker: WULF Paul Oliver (Tessmar)MISHRA Sachin (Stark)OGZUC Olivia (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-02-02, Time: 12:30:00, Speaker: COSTANTINI Elena (Tanaka)VIOHL Niklas (Köhler)LEON-RUIZ Jesus (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-02-09, Time: 12:30:00, Speaker: MIOCIC-STOSIC Fran (Zagrovic)BELL Caelan (Gerlich)KLEINWAECHTER Ava (Slade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-02-16, Time: 12:30:00, Speaker: HOFMANN Maura (Van der Veeken)SEN Zeynep Begüm (Ma)ZEN PETISCO FIORE Ana Paula (Urban), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-02-23, Time: 12:30:00, Speaker: JANKOWSKA Julia (Ameres)DOCAVO GARCIA Antonio (Jachowicz)HAONAN Bao (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-03-02, Time: 12:30:00, Speaker: RUSSETT Colleen (Berger)ZEILER Christine (Kovarik)HOLLAUS David (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2026-03-09, Time: 12:30:00, Speaker: GUZMAN PEREZ Sebastian (Martinez)ROFFAY Chloe (Pinheiro)BHARDWAJ Vishakha (Schlögelhofer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None