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Physiological processes are driven by the coordinated action of organs, tissues and cells. Coordination of these activities allows organisms to respond appropriately to their changing environment. Within cells themselves, important metabolic processes are often compartmentalised by membranes, which necessitates the flow of information between compartments. How is this information integrated into the appropriate downstream response? We try to understand the basic principles that govern the flow of information in cells with particular emphasis on the role of lipid second messengers. By understanding the mechanisms by which these signals are transduced and propagated, we can better answer why and how things go wrong in disease.
We study how lipids regulate the activity of signaling enzymes, including both protein kinases and phosphatases. We use biochemical and cell biological assays supported by biophysical and structural techniques to deduce how, where, and when the signal is transduced. Our work is underpinned by quantitative biochemistry performed with precisely defined macromolecules. The insights we derive have the potential to rationalize disease pathogenesis at the molecular and atomic levels. For example, in the pro-growth and survival kinase Akt, we have characterized the mechanism by which a mutation associated with cancer and overgrowth disorders leads to kinase activity that is both spatially and temporally de-regulated. Determining how specific mutations drive the development of disease is essential for effective therapeutic intervention.
Thomas studied Biochemistry at the University of Bristol, U.K. before obtaining a PhD in Structural Biology at the MRC Laboratory of Molecular Biology in Cambridge. Thomas moved to the USA in 2005 as an EMBO postdoctoral fellow at the National Institutes of Health in Bethesda, MD and started his own lab as an independent investigator at the Max Perutz Labs in 2012.
Campus Vienna Biocenter 5
1030 Vienna
Room: 1.616
+43-1-4277-52205
The regulation of protein kinase activity by activation loop phosphorylation is a well-characterized mechanism. Protein kinases that auto-phosphorylate usually do so in trans: dimerization results in reciprocal phosphorylation of the activation loop by the other protomer. However, we have discovered that Protein Kinase D (PKD) has evolved the inverse solution to the same problem. PKD is an inactive dimer that is activated by kinase domain dissociation followed by cis-autophosphorylation (Reinhardt et al, PNAS, 2023).
The myotonic dystrophy kinases of the DMPK family are conserved regulators of actomyosin contractility. The four prototypical DMPK members are obligate homodimers with a conserved architecture of N-terminal kinase domains, a central coiled-coil, and C-terminal membrane binding domains. Remarkably, the length of the coiled-coil domain of each family member varies between 10 and 145 nm, but is astonishingly well conserved. We present a model in which the activity of these kinases is regulated by their spatial positioning with respect to the membrane (Truebestein et al, Structure, 2023).
Phosphoinositide-dependent kinase 1 (PDK1) is an essential protein kinase that controls cellular and organismal growth. We have elucidated the mechanism by which PDK1 is activated by phosphatidylinositol-3,4,5-trisphosphate (PIP3) at the plasma membrane in response to growth factor-mediated activation of cell surface receptors. Our work reveals previously unknown mechanisms of autoinhibition and trans-autoactivation, with opportunities for the development of novel therapeutics in the treatment of cancer (Levina et al, Nature Communications, 2022).
© Illustration by Dorotea Fracchiolla (Art&Science)
The lipid second messengers PI(3,4,5)P3 and PI(3,4)P2 have long been known to activate Akt by recruiting it to membranes, where it is activated by phosphorylation. We have determined the structure of autoinhibited Akt1, revealing the molecular basis of a disease-causing mutation in the PH domain which gives rise to Proteus Syndrome and some cancers. Phosphorylation is insufficient to fully activate Akt1. Our work implies that Akt signaling is restricted to discrete membrane locations in the cell (Truebestein et al, PNAS, 2021).
Serum- and glucocorticoid-regulated kinase 3 (Sgk3) is activated by the phospholipid phosphatidylinsoitol 3-phosphate (PI3P) in the PI3 kinase pathway. Up-regulation of Sgk3 activity has increasingly been implicated in cancers that exhibit paradoxically low Akt activity. We have discovered that Sgk3 is dependent on PI3P for its activity, which restricts its activity to PI3P-rich endosomes in cells. We have biochemically reconstituted Sgk3 activation downstream of the class III PI 3-kinase Vps34 in vitro (Pokorny et al, Journal of Biological Chemistry, 2021).
Protein Kinase D (PKD) is an essential ser/thr kinase involved in vesicular transport of cargo from the trans-Golgi network to the plasma membrane. We have discovered a novel, ubiquitin-like domain in PKD that mediates its dimerization on diacylglycerol-containing membranes, thereby driving trans-autophosphorylation and activation of its kinase domain (Elsner et al, Journal of Biological Chemistry, 2019).
The protein kinase Akt integrates signals from membrane-embedded lipid second messengers and signals in the form of phosphorylation by upstream protein kinases. We have shown that one without the other is insufficient for Akt activation and that membrane dissociation triggers rapid dephosphorylation and inactivation of Akt (Lučić et al, PNAS, 2018).
We recently demonstrated that the activity of a protein kinase called Akt, which promotes cell growth and proliferation, is strictly governed by the engagement of two specific lipids in cell membranes (Ebner & Lučić et al, Molecular Cell, 2017). Bypassing this requirement leads to uncontrolled growth and cancer.
We have discovered an allosteric switch in the Src and Tec kinases that converts them into active enzymes by promoting the exchange of ADP for ATP (von Raußendorf et al, Scientific Reports, 2017). The switch depends on recognition of a polyproline motif in the tail of activated receptors at the plasma membrane.
Rho-associated coiled-coil kinase (ROCK) is a key signal transducer in regulating the cytoskeleton. Substrate engagement is controlled by the precise positioning of its kinase domains, which is achieved via a long coiled-coil domain that bridges its membrane binding domains to its kinase domains (Truebestein et al., Nature Communications, 2016).
Membranes are sites of intense signaling activity in eukaryotic cells. Essential processes such as autophagy, cytokinesis, exo- and endo- cytosis, and cytoskeletal remodeling depend on signal propagation at cellular membranes. Dysregulation of signal transduction at these sites is the cause of a number of hereditary and non-hereditary diseases, including Coffin-Lowry syndrome, spinocerebellar ataxia, myotonic dystrophy, and various cancers. Over 500 kinases and 130 phosphatases regulate signal transduction by phosphorylating or dephosphorylating their target proteins. Given that the chemistry of phosphoryl transfer is conserved, there is a clear need for compartmentalization of what are essentially the same chemical reactions.
One of the most important consequences of the activation of cell surface receptors is the generation of small molecule second messengers. In addition to the freely diffusible second messengers such as cAMP and inositol-1,4,5-triphosphate (IP3), a number of cellular second messengers are lipids. Despite being of fundamental importance to the exquisite spatial and temporal regulation of many cellular processes, the molecular mechanisms of lipid-mediated signal transduction are not well understood. Our goal is to understand how lipid second messengers can turn on signaling pathways at the membrane. To achieve this, we are using a spectrum of biophysical (including X-ray crystallography), biochemical, and cell biological techniques. Fundamentally, we aim to describe signal transduction processes with deep mechanistic insight. By combining structure with quantitative in vitro biochemistry on rigorously validated samples, we can probe the structure-function relationship in absolute terms.
Many of the lipid responsive human protein kinases belong to the AGC family of kinases, of which paradigmatic lipid-activated kinases are Akt, PDK1 and Sgk3. In 2017 we demonstrated the allosteric activation of Akt by the lipid second messengers PI(3,4,5)P3 and PI(3,4)P2 for the first time. A mutation in the kinase domain associated with cancer and overgrowth disorders of the brain causes Akt hyperactivation by relieving autoinhibition (Ebner and Lučić et al., Molecular Cell 2017). We have since described the mechanism of activation in more detail (Truebestein et al., PNAS 2021) and characterized the allosteric coupling between PH domain-mediated autoinhibition and the inactivation of Akt by dephosphorylation (Lučić et al., PNAS 2018). Conceptually, Akt can be thought of as an AND gate that integrates multiple signals to drive the biological response.
Similarly, Sgk3 employs similar mechanisms of autoinhibition and allosteric activation to drive signaling downstream of the lipid second messenger PI3P. Like Akt, Sgk3 exhibits an inactive conformation in the absence of PI3P in which the PI3P-binding pocket is sequestered in an intramolecular interface between the regulatory and kinase domains (Pokorny et al, Journal of Biological Chemistry 2021). Akt and Sgk3 activities are thereby restricted, exclusively, to those membranes in the cell where they can be activated by their cognate lipids.
Protein kinases are often activated by autophosphorylation of a key residue in their activation loop that drives catalytic activity. Mechanistically, this reaction may occur in trans or in cis. In 2019, we determined the structure of a novel ubiquitin-like domain in Protein Kinase D (PKD) which mediates its dimerization (Elsner et al., Journal of Biological Chemistry 2019). PKD, however, is maintained in an inactive conformation by dimerization and relief of this trans-autoinhibition leads to activation loop autophosphorylation in cis (Reinhardt et al., PNAS 2023). PKD is an essential mammalian kinase involved in trafficking of cargo destined for secretion from the trans-Golgi network to the plasma membrane.
In a parallel study on phosphoinositide-dependent kinase 1 (PDK1), which is a master regulator of growth factor signaling, we have determined the mechanism of its activation by PIP3-elicited dimerization and trans-autophosphorylation (Levina et al., Nature Communications 2022). These studies showcase how nature has employed common strategies, such as dimerization and activation loop phosphorylation, in different ways to control signal transduction.
In work on the Tec and Src family tyrosine kinases, we have revealed a previously unknown switch in nucleotide binding that drives kinase activation (von Raußendorf et al., Sci Rep 2017). Here nature utilizes ADP, the product of the kinase reaction, to stabilize and maintain the inactive conformation. Upon triggering of the conformational changes required for kinase activation, these kinases lose their strict preference for ADP, which is then rapidly exchanged for ATP in the cell. The binding of ADP in the inactive conformation serves to insulate the kinase from promiscuous activity, while activation drives the exchange of ADP for the ATP required for substrate phosphorylation.
We are also interested in how signal transduction pathways are organized. Scaffolding of signaling proteins in the same pathway enhances specificity, promotes signal amplification by reducing noise, and, ultimately, improves signal propagation through the pathway. Membranes act as the scaffolds for many signaling reactions, including those involved in regulation of the actin cytoskeleton (Truebestein et al., Nature Communications 2016; Truebestein et al., Structure 2023). Our studies are aimed at understanding how diverse signals are integrated, how substrate specificity is encoded not just at the kinase level, and the influence of the membrane environment on multi-component signaling hubs. This is an exciting area of research with frontiers in ageing, cancer, metabolic diseases such as diabetes, and obesity.
Sumire Antonioli
PhD Student +43-1-4277-52241
Room: 1.222
Eva Krötenheerdt
PhD Student +43-1-4277-52241
Room: 1.222
Thomas Leonard
Group Leader +43-1-4277-52205
Room: 1.616
Vanessa Meier
Diploma/Master Student +43-1-4277-52241
Room: 1.222
Magdalena Otto
PhD Student +43-1-4277-52275
Room: 1.321
Lucas Piëch
PhD Student +43-1-4277-52241
Room: 1.222
Julia Westermayer
Lab Manager +43-1-4277-52241
Room: 1.608
Felix Wolkenstein
+43-1-4277-52241
Room: 1.222
Congratulations to Eva Krötenheerdt, who has won the 2024 VBC PhD Program ‘Out of the Box’ Award. Eva, together with Julia Kober (Ramundo Lab, GMI), proposed an innovative approach to build single molecule reaction chambers, which they hope to use to resolve a long-standing question in kinase biology: do kinases autophosphorylate in cis or trans? The project’s interdisciplinary, inter-institute collaboration, and potential for high-impact discoveries convinced the jury!
If you are interested in the mechanisms by which cells faithfully execute their metabolic and developmental programs, you are right at home in the Leonard Lab. We are interested in smart, motivated, and ambitious people who want to understand, at a molecular and mechanistic level, how cells signal with high fidelity in space and time. We are hiring at the Master, PhD and Postdoc levels, so please reach out to us if you want to learn more!
Congratulations to Lucas Piëch, who has been awarded the Max Perutz PhD Fellowship for his proposal on PDK1. PDK1 is an essential kinase that regulates cellular and organismal growth. Lucas is interested in the mechanisms by which PDK1 is kept inactive in the absence of a signal and, conversely, how it is activated at the plasma membrane.
Ronja defended her PhD thesis with an outstanding explanation of kinase activation by autophosphorylation that was understandable to a non-expert audience. Ronja's work on Protein Kinase D (PKD) has revealed an unexpected mechanism of kinase regulation by trans-autoinhibition, which is relieved by a combination of membrane binding and cis-autophosphorylation. Ronja's work has major implications for the regulation of other protein kinases that are widely believed to be activated by trans-autophosphorylation.
In this Review Article, just published in eLife, we examine the mechanistic basis for protein kinase activation by autophosphorylation. We critically evaluate the evidence for both cis (intramolecular) and trans (intermolecular) mechanisms, summarise the advantages and pitfalls of common experimental approaches, and encourage more quantitative and specific reporting.
In this Review Article, just published in Developmental Cell, Thomas Leonard, Martin Loose and Sascha Martens discuss membrane-localized reactions with a particular focus on insights derived from reconstituted systems. The authors explain how the interplay of regulatory proteins results in the self-organization of cellular factors, their condensation, assembly, and activity.
The PI is perfectly normal - honestly. 2 years after his students bought him a bungee jump for becoming a tenured Professor at the Max Perutz Labs, Thomas thanked them all and stepped off Jauntalbrücke in Carinthia, Austria for a 96 m plunge towards the river below. Sadly, none of his students could be convinced to jump with him. Check out the video to see what students can do for their PI!
Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase.
Truebestein, Linda; Antonioli, Sumire; Waltenberger, Elisabeth; Gehin, Charlotte; Gavin, Anne-Claude; Leonard, Thomas A
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis.
Reinhardt, Ronja; Hirzel, Kai; Link, Gisela; Eisler, Stephan A; Hägele, Tanja; Parson, Matthew A H; Burke, John E; Hausser, Angelika; Leonard, Thomas A
Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation.
Levina, Aleksandra; Fleming, Kaelin D; Burke, John E; Leonard, Thomas A
Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.
Truebestein, Linda; Hornegger, Harald; Anrather, Dorothea; Hartl, Markus; Fleming, Kaelin D; Stariha, Jordan T B; Pardon, Els; Steyaert, Jan; Burke, John E; Leonard, Thomas A
In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate.
Pokorny, Daniel; Truebestein, Linda; Fleming, Kaelin D; Burke, John E; Leonard, Thomas A
A ubiquitin-like domain controls Protein Kinase D dimerization and activation by trans-autophosphorylation.
Elsner, Daniel J; Siess, Katharina M; Gossenreiter, Thomas; Hartl, Markus; Leonard, Thomas A
Conformational sampling of membranes by Akt controls its activation and inactivation.
Lučić, Iva; Rathinaswamy, Manoj K; Truebestein, Linda; Hamelin, David J; Burke, John E; Leonard, Thomas A
PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes
Michael Ebner, Iva Lučić, Thomas A. Leonard, and Ivan Yudushkin
A molecular ruler regulates cytoskeletal remodelling by the Rho kinases
Truebestein, L., Elsner, D.J., Fuchs, E., Leonard, T.A.
Project title: 'Phosphoinositide-dependent kinase 1: master growth regulator' (P 36212)
Project title: 'PI3K signaling- navigating upstream and downstream of Akt' (P 33066)
Project title: 'Structure, function and regulation of Protein Kinase D' (P 30584)
The Leonard Group is a member of the special doctoral program 'Signaling Mechanisms in Cellular Homeostasis (W1261)', reviewed and funded by the Austrian Science Fund (renewed for second funding period, 2021-2025).
Project title: 'Microtubule-associated serine/threonine kinases in health and disease' (P 36724)
Project title: 'PHLPP – elucidating the mechanism of action of a tumor suppressor phosphatase' (BG 05/2023)
Accessing the Nanoscale with Light
14:00
VBC5, Lecture hall B/Zoom
Kristina Djinovic-Carugo
Francisco BalzarottiDate: 2024-11-21, Time: 14:00:00, Speaker: Francisco Balzarotti, Location: VBC5, Lecture hall B/Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: IMP, Host: Kristina Djinovic-Carugo
Molecular Environmental Science: Linking carbon and metal biogeochemical cycles from molecular to landscape scales
12:00 Zoom Stephan Krämer Sharon BoneDate: 2024-11-21, Time: 12:00:00, Speaker: Sharon Bone, Location: Zoom, Type: CeMESS Lecture Series, Institute: Stanford University, Host: Stephan Krämer
Structures and mechanisms of prokaryotic genome defence systems
11:00 Zoom Irma Querques Martin JinekDate: 2024-11-21, Time: 11:00:00, Speaker: Martin Jinek, Location: Zoom, Type: VBC Regular Seminar, Institute: University of Zurich, Host: Irma Querques
Exploring Light and Carbon Dynamics in the Green Microalga Chlamydomonas reinhardtii
11:30 IMBA/GMI Lecture Hall Silvia Ramundo Dimitris PetroutsosDate: 2024-11-22, Time: 11:30:00, Speaker: Dimitris Petroutsos, Location: IMBA/GMI Lecture Hall, Type: GMI Seminar, Institute: Uppsala University, Host: Silvia Ramundo
Monday Seminar (Internal)
12:30 IMP Lecture Hall BOREIKAITE Vytaute (Plaschka), SRINIVASAN Navaneeth (Peters), DODOMANI Ananya (Campbell)Date: 2024-11-25, Time: 12:30:00, Speaker: BOREIKAITE Vytaute (Plaschka)SRINIVASAN Navaneeth (Peters)DODOMANI Ananya (Campbell), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Understanding starch granule biosynthesis in plants using insights from natural variation
11:45 IMBA/GMI Lecture Hall Yan Ma David SeungDate: 2024-11-29, Time: 11:45:00, Speaker: David Seung, Location: IMBA/GMI Lecture Hall, Type: GMI Seminar, Institute: John Innes Centre, Norwich, Host: Yan Ma
Exploring the cell biology that enables efficient photosynthesis in C4 plants
11:00 IMBA/GMI Lecture Hall Yan Ma Tina SchreierDate: 2024-11-29, Time: 11:00:00, Speaker: Tina Schreier, Location: IMBA/GMI Lecture Hall, Type: GMI Seminar, Institute: University of Oxford, Host: Yan Ma
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SOMMER Theresa (Rivron), KRACHT Laura (Knoblich), MAIR Zahar (Dolan)Date: 2024-12-02, Time: 12:30:00, Speaker: SOMMER Theresa (Rivron)KRACHT Laura (Knoblich)MAIR Zahar (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Photomimetism for Marine Photosymbioses in Captivity: Simulating Tidal Cycles with Light
13:15 UBB - Lecture Hall 1 Uli Technau Xavier BaillyDate: 2024-12-03, Time: 13:15:00, Speaker: Xavier Bailly, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Station Biologique de Roscoff, Host: Uli Technau
Sense and Sensibility - Regulation of innate immune sensors
14:00 IMP Lecture Hall Moritz Gaidt Konstantin SparrerDate: 2024-12-04, Time: 14:00:00, Speaker: Konstantin Sparrer, Location: IMP Lecture Hall, Type: Impromptu Seminar, Institute: Universitätsklinikum Ulm, Host: Moritz Gaidt
The dynamic chaperone network in the endoplasmatic reticulum
14:00 Lecture Hall B, VBC5 & Zoom Elif Karagöz Sebastian HillerDate: 2024-12-05, Time: 14:00:00, Speaker: Sebastian Hiller, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Biozentrum Basel, Host: Elif Karagöz
Microbial necromass in soil: its impact on soil properties and the fate of compounds and chemicals
12:00 UBB - Lecture Hall 2 & Zoom Christina Kaiser Matthias KästnerDate: 2024-12-05, Time: 12:00:00, Speaker: Matthias Kästner, Location: UBB - Lecture Hall 2 & Zoom, Type: CeMESS Lecture Series, Institute: Helmholtz-Centre for Environmental Research, Host: Christina Kaiser
Biophysical and cellular analysis of mitotic human chromosomes
11:00 IMBA/GMI Lecture Hall Joao Matos Ian HicksonDate: 2024-12-05, Time: 11:00:00, Speaker: Ian Hickson, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Joao Matos
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BREHM Martin (Falk), PLATZER Sebastian (Hein), RAFANEL Baptiste (Brennecke)Date: 2024-12-09, Time: 12:30:00, Speaker: BREHM Martin (Falk)PLATZER Sebastian (Hein)RAFANEL Baptiste (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Studying stem cells and regeneration across the tree of life using single cell transcriptomics
13:15 UBB - Lecture Hall 1 Tim Wollesen Jordi SolanaDate: 2024-12-10, Time: 13:15:00, Speaker: Jordi Solana, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: University of Exeter, Host: Tim Wollesen
Consequences (and causes) of mitotic checkpoint dysfunction
11:30 Max Perutz Labs SR 1 (6.501) Christopher Campbell Gerben VaderDate: 2024-12-10, Time: 11:30:00, Speaker: Gerben Vader, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: Cancer Center Amsterdam, Host: Christopher Campbell
Title to be announced
14:00 Lecture Hall B, VBC5 & Zoom Kristina Djinovic-Carugo Shotaro OtsukaDate: 2024-12-12, Time: 14:00:00, Speaker: Shotaro Otsuka, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Max Perutz Labs, Host: Kristina Djinovic-Carugo
Cryo-EM structures provide new insights into DNA repair
11:00 IMBA/GMI Lecture Hall Joao Matos Stephen WestDate: 2024-12-12, Time: 11:00:00, Speaker: Stephen West, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: The Francis Crick Institute, Host: Joao Matos
Sex chromosome, symbiosis, and CO2-concentrating mechanism: the secret life of hornworts
11:30 GMI Orange Seminar Room Fred Berger Fay-Wie LiDate: 2024-12-13, Time: 11:30:00, Speaker: Fay-Wie Li, Location: GMI Orange Seminar Room, Type: GMI Seminar, Institute: Cornell University/Boyce Thompon Institute, Host: Fred Berger
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DAHAN Tal (Nordborg), CHUGUNOVA Anastasia (Pauli), VON WIREN Julius (Kovarik)Date: 2024-12-16, Time: 12:30:00, Speaker: DAHAN Tal (Nordborg)CHUGUNOVA Anastasia (Pauli)VON WIREN Julius (Kovarik), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Mining Immunological Memory from Previous Generations
13:15 UBB - Lecture Hall 1 Silvia Bulgheresi Matthias R. SchaeferDate: 2024-12-17, Time: 13:15:00, Speaker: Matthias R. Schaefer, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Medical University of Vienna, Host: Silvia Bulgheresi
Title to be announced
14:00 Lecture Hall B, VBC5 & Zoom Thomas Juffmann Sergi Padilla-ParraDate: 2025-01-09, Time: 14:00:00, Speaker: Sergi Padilla-Parra, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: King's College London, Host: Thomas Juffmann
Cancer aneuploidy: From selection pressures to cellular vulnerabilities
11:00 IMBA/GMI Lecture Hall Anna Obenauf Uri Ben-DavidDate: 2025-01-09, Time: 11:00:00, Speaker: Uri Ben-David, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Tel Aviv University, Host: Anna Obenauf
Monday Seminar (Internal)
12:30 IMP Lecture Hall KRASNOVID Filipp (Mari-Ordonez), ROTHE Patricia (Plaschka), KROGULL Daniel (Burga)Date: 2025-01-13, Time: 12:30:00, Speaker: KRASNOVID Filipp (Mari-Ordonez)ROTHE Patricia (Plaschka)KROGULL Daniel (Burga), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
11:00 IMBA/GMI Lecture Hall Irma Querques Stan BrounsDate: 2025-01-16, Time: 11:00:00, Speaker: Stan Brouns, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Delft University of Technology, Host: Irma Querques
Monday Seminar (Internal)
12:30 IMP Lecture Hall VICIC Ziga (Jachowicz), GRÜNEWALD Jakob (Obenauf), MANOLOVA Toni (Falk)Date: 2025-01-20, Time: 12:30:00, Speaker: VICIC Ziga (Jachowicz)GRÜNEWALD Jakob (Obenauf)MANOLOVA Toni (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
14:00 Lecture Hall B, VBC5 & Zoom Bojan Zagrovic Gasper TkacikDate: 2025-01-23, Time: 14:00:00, Speaker: Gasper Tkacik, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: ISTA, Host: Bojan Zagrovic
Title to be announced
11:00 UBB - Lecture Hall 2 & Zoom Hayk Palabikyan Anais CarioDate: 2025-01-23, Time: 11:00:00, Speaker: Anais Cario, Location: UBB - Lecture Hall 2 & Zoom, Type: DOME Lecture Series, Institute: French National Centre for Scientific Research, Host: Hayk Palabikyan
Title to be announced
11:00 IMBA/GMI Lecture Hall Egon Ogris Anne BertolottiDate: 2025-01-23, Time: 11:00:00, Speaker: Anne Bertolotti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MCR Laboratory of Molecular Biology, Host: Egon Ogris
Title to be announced
10:00 IMBA/GMI Lecture Hall Andi Pauli Ori AvinoamDate: 2025-01-26, Time: 10:00:00, Speaker: Ori Avinoam, Location: IMBA/GMI Lecture Hall, Type: IMP Impromptu Seminar, Institute: Weizmann Institute, Host: Andi Pauli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WILLIAMS Thomas (Clausen), SCARAMUZZA Federico (Tessmar), WALTER Mateusz (Querques)Date: 2025-01-27, Time: 12:30:00, Speaker: WILLIAMS Thomas (Clausen)SCARAMUZZA Federico (Tessmar)WALTER Mateusz (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Decidualisation of human endometrium: from evolutionary insights to novel mechanisms of disease
13:15 UBB - Lecture Hall 1 Mihaela Pavlicev Jan BrosensDate: 2025-01-28, Time: 13:15:00, Speaker: Jan Brosens, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: University of Warwick, Host: Mihaela Pavlicev
Title to be announced
11:00 GMI Orange Seminar Room Nicolas Rivron Jan BrosensDate: 2025-01-29, Time: 11:00:00, Speaker: Jan Brosens, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: University of Warwick, Host: Nicolas Rivron
Title to be announced
14:00 Lecture Hall B, VBC5 & Zoom Ivan Yudushkin Marcus TaylorDate: 2025-01-30, Time: 14:00:00, Speaker: Marcus Taylor, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Max Planck Institute for Infection Biology, Berlin, Host: Ivan Yudushkin
Reactive Tracers in Chemical Substances: Compound-specific Isotope Analysis to Characterize Transformation of Organic Compounds
12:00 Zoom Thilo Hofmann Martin ElsnerDate: 2025-01-30, Time: 12:00:00, Speaker: Martin Elsner, Location: Zoom, Type: CeMESS Lecture Series, Institute: Technical University of Munich, Host: Thilo Hofmann
Title to be announced
11:00 IMBA/GMI Lecture Hall Julius Brennecke Maria-Elena Torres-PadillaDate: 2025-01-30, Time: 11:00:00, Speaker: Maria-Elena Torres-Padilla, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Ludwig-Maximilians-University Munich, Host: Julius Brennecke
Monday Seminar (Internal)
12:30 IMP Lecture Hall CRUZ Joseph (Gerlich), GHEORGHITA Andreea (Clausen), GALUSKA Philipp (Djinovic)Date: 2025-02-03, Time: 12:30:00, Speaker: CRUZ Joseph (Gerlich)GHEORGHITA Andreea (Clausen)GALUSKA Philipp (Djinovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
11:00 GMI Orange Seminar Room Alex Stark Dominic GruenDate: 2025-02-04, Time: 11:00:00, Speaker: Dominic Gruen, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: University of Würzburg, Host: Alex Stark
Ectomycorrhizal fungi as drivers of forest ecosystem processes
12:00 UBB - Lecture Hall 2 & Zoom Mark Anthony Filipa CoxxDate: 2025-02-06, Time: 12:00:00, Speaker: Filipa Coxx, Location: UBB - Lecture Hall 2 & Zoom, Type: CeMESS Lecture Series, Institute: University of Manchester, Host: Mark Anthony
Title to be announced
11:00 IMBA/GMI Lecture Hall Fred Berger Thibaut BrunetDate: 2025-02-06, Time: 11:00:00, Speaker: Thibaut Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institut Pasteur, University Paris-Cite, Host: Fred Berger
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GRIGOREVA Elizaveta (Nordborg), KOHOUTKOVA Eliska (Clausen), STEINACKER Thomas (Gerlich)Date: 2025-02-10, Time: 12:30:00, Speaker: GRIGOREVA Elizaveta (Nordborg)KOHOUTKOVA Eliska (Clausen)STEINACKER Thomas (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Fred Berger Jeff BoekeDate: 2025-02-13, Time: 11:00:00, Speaker: Jeff Boeke, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: NYU Langdone Health, Host: Fred Berger
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RAFFL Gerald (Ameres), VULIN Milica (Obenauf), FISCHER Andre (Tanaka)Date: 2025-02-17, Time: 12:30:00, Speaker: RAFFL Gerald (Ameres)VULIN Milica (Obenauf)FISCHER Andre (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Dea Slade Gaia NovarinoDate: 2025-02-20, Time: 11:00:00, Speaker: Gaia Novarino, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: ISTA, Host: Dea Slade
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BAYERL Jonas (Zuber), ZABOLOCKI Michael (Knoblich), EDER Stephanie (Zimmer)Date: 2025-02-24, Time: 12:30:00, Speaker: BAYERL Jonas (Zuber)ZABOLOCKI Michael (Knoblich)EDER Stephanie (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz Cedric FeschotteDate: 2025-02-27, Time: 11:00:00, Speaker: Cedric Feschotte, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Cornell University, Host: Joanna Jachowicz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KROETENHEERDT Eva (Leonard), RÖHSNER Josef (Pauli), RIABOV Daria (Plaschka)Date: 2025-03-03, Time: 12:30:00, Speaker: KROETENHEERDT Eva (Leonard)RÖHSNER Josef (Pauli)RIABOV Daria (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None CHO Chung Hyun (Berger), SEIDL Carina (Tanaka), MIGOTTI Mario (Konrat)Date: 2025-03-10, Time: 12:30:00, Speaker: CHO Chung Hyun (Berger)SEIDL Carina (Tanaka)MIGOTTI Mario (Konrat), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
SY-Stem
Mar 12 - Mar 14 IMP Lecture Hall NoneDate: 2025-03-12, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None CHEN Shenzhi (Stark), BINDL Michael (Leeb), JÄGER Martin (Obenauf)Date: 2025-03-17, Time: 12:30:00, Speaker: CHEN Shenzhi (Stark)BINDL Michael (Leeb)JÄGER Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Unravelling the inner secrets of cells with live-cell super-resolution microscopy
10:00 Lecture Hall A, VBC 5 Jonas Ries Francesca BottanelliDate: 2025-03-19, Time: 10:00:00, Speaker: Francesca Bottanelli, Location: Lecture Hall A, VBC 5, Type: Impromptu Seminar, Institute: Freie Universität Berlin, Host: Jonas Ries
Title to be announced
11:00 IMBA/GMI Lecture Hall Joao Matos Geert KopsDate: 2025-03-20, Time: 11:00:00, Speaker: Geert Kops, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Joao Matos
Monday Seminar (Internal)
12:30 IMP Lecture Hall None MAYA Juan (Balzarotti), DOSA Anna (Clausen), KOBER Julia (Ramundo)Date: 2025-03-24, Time: 12:30:00, Speaker: MAYA Juan (Balzarotti)DOSA Anna (Clausen)KOBER Julia (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alwin Köhler Martin BeckDate: 2025-03-27, Time: 11:00:00, Speaker: Martin Beck, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Biophysics, Host: Alwin Köhler
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HOLZER Elisabeth (Martens), THEMANN Jan (Knoblich), GROSS Angelina (Dagdas)Date: 2025-03-31, Time: 12:30:00, Speaker: HOLZER Elisabeth (Martens)THEMANN Jan (Knoblich)GROSS Angelina (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Sebastian Falk Rotem SorekDate: 2025-04-03, Time: 11:00:00, Speaker: Rotem Sorek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute, Host: Sebastian Falk
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GROH Roan (Dagdas), CHAO Victor (Huis), KHANDEKAR Ameya (Ellis)Date: 2025-04-07, Time: 12:30:00, Speaker: GROH Roan (Dagdas)CHAO Victor (Huis)KHANDEKAR Ameya (Ellis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
"Tiles of Life" Symposium
Apr 10 - Apr 11 IMP Lecture Hall SMICH communityDate: 2025-04-10, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall , Type: Symposium, Institute: None, Host: SMICH community
Tiles of Life - Student Symposium
Apr 10 - Apr 11 IMP lecture hall, Vienna BioCenterThe symposium will explore the intricate "tiles" that form the vast and diverse fields of molecular biology and aims to foster discussions and inspire collaborations by bringing the “tiles of life” together. The program includes several talks by esteemed and international speakers sharing their latest findings to link the molecular mosaic of the cell - from structures to organisms. Additionally, we will highlight the research of the SMICH community on campus by complementing the program with student talks.
Monday Seminar (Internal)
12:30 IMP Lecture Hall None OKUN Anastasia (Karagöz), COLLISON Robert (Ramundo), WELZL Paul (Balzarotti/Plaschka)Date: 2025-04-14, Time: 12:30:00, Speaker: OKUN Anastasia (Karagöz)COLLISON Robert (Ramundo)WELZL Paul (Balzarotti/Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Anton Goloborodko Maria Cristina GambettaDate: 2025-04-24, Time: 11:00:00, Speaker: Maria Cristina Gambetta, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lausanne, Host: Anton Goloborodko
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SUWITA Johannes (Pauli), GRABARCZYK Daniel (Clausen), PANDA Aswini (Falk)Date: 2025-04-28, Time: 12:30:00, Speaker: SUWITA Johannes (Pauli)GRABARCZYK Daniel (Clausen)PANDA Aswini (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KIM Olena (Knoblich), JOB Nikhil (Dolan), ADELMANN Leonie (Raible)Date: 2025-05-05, Time: 12:30:00, Speaker: KIM Olena (Knoblich)JOB Nikhil (Dolan)ADELMANN Leonie (Raible), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Microsymposium on RNA Biology'
May 07 - May 09 IMP Lecture Hall NoneDate: 2025-05-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
EMBO meeting on RNA meets Protein decay
May 11 - May 14 IMP Lecture Hall NoneDate: 2025-05-11, Time: 14:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SCIBISZ Grzegorz (Karagöz), VAN GENDEREN Emiel (Rivron), BOZKURT Miray (Tanaka)Date: 2025-05-12, Time: 12:30:00, Speaker: SCIBISZ Grzegorz (Karagöz)VAN GENDEREN Emiel (Rivron)BOZKURT Miray (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alex Stark Chuna Ram ChoudharyDate: 2025-05-15, Time: 11:00:00, Speaker: Chuna Ram Choudhary, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Alex Stark
Monday Seminar (Internal)
12:30 IMP Lecture Hall None POTTENDORFER Elisabeth (Obenauf), WALLNER Eva-Sophie (Dolan), BECKER Moritz (Leeb)Date: 2025-05-19, Time: 12:30:00, Speaker: POTTENDORFER Elisabeth (Obenauf)WALLNER Eva-Sophie (Dolan)BECKER Moritz (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Elif Karagöz Manuel LeonettiDate: 2025-05-22, Time: 11:00:00, Speaker: Manuel Leonetti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: CZ Biohub San Francisco, Host: Elif Karagöz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIMITROVA Polina (Van der Veeken), STRAVS Ana (Knoblich), SCHÖNLEIN Martin (Obenauf)Date: 2025-05-26, Time: 12:30:00, Speaker: DIMITROVA Polina (Van der Veeken)STRAVS Ana (Knoblich)SCHÖNLEIN Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SABATH Kevin (Plaschka/Stark), MANCHENO JUNCOSA Estela (Mendjan), HORENKAMP Simone (Tanaka)Date: 2025-06-02, Time: 12:30:00, Speaker: SABATH Kevin (Plaschka/Stark)MANCHENO JUNCOSA Estela (Mendjan)HORENKAMP Simone (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Julius Brennecke Stefan MundlosDate: 2025-06-12, Time: 11:00:00, Speaker: Stefan Mundlos, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Molecular Genetics, Host: Julius Brennecke
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BERGER Sonja (Goloborodko), KOWALD Saskia (Gaidt), KAPRAL Thomas (Zagrovic)Date: 2025-06-16, Time: 12:30:00, Speaker: BERGER Sonja (Goloborodko)KOWALD Saskia (Gaidt)KAPRAL Thomas (Zagrovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joris Van der Veeken Nikhil JoshiDate: 2025-06-18, Time: 11:00:00, Speaker: Nikhil Joshi, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Yale University, Host: Joris Van der Veeken
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BUCHERON Chloe (Menche), KRUMWIEDE Luisa (Gaidt), PACHANO Tomas (Stark)Date: 2025-06-23, Time: 12:30:00, Speaker: BUCHERON Chloe (Menche)KRUMWIEDE Luisa (Gaidt)PACHANO Tomas (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SCHINDLER Lukas (Schlögelhofer), MANDLBURGER Nikolaus (Stark), OTTO Magdalena (Leonard)Date: 2025-06-30, Time: 12:30:00, Speaker: SCHINDLER Lukas (Schlögelhofer)MANDLBURGER Nikolaus (Stark)OTTO Magdalena (Leonard), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Marco Hein Matthias MannDate: 2025-07-03, Time: 11:00:00, Speaker: Matthias Mann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max-Planck Institute of Biochemistry, Host: Marco Hein
Monday Seminar (Internal)
12:30 IMP Lecture Hall None TRUS Palina (Peters), KOBAKHIDZE George (Dong), KONGSTED Thea (Dolan)Date: 2025-07-07, Time: 12:30:00, Speaker: TRUS Palina (Peters)KOBAKHIDZE George (Dong)KONGSTED Thea (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Erinc Hallacli Simon AlbertiDate: 2025-07-10, Time: 11:00:00, Speaker: Simon Alberti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: TU Dresden, Host: Erinc Hallacli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RUSCH Emma (Golobordko), VELIKOV Daniel (Matos), VOGEL Alexander (Clausen/Yudushkin)Date: 2025-07-14, Time: 12:30:00, Speaker: RUSCH Emma (Golobordko)VELIKOV Daniel (Matos)VOGEL Alexander (Clausen/Yudushkin), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Moritz Gaidt Vishva DixitDate: 2025-07-17, Time: 11:00:00, Speaker: Vishva Dixit, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Genentech, Host: Moritz Gaidt
Monday Seminar (Internal)
12:30 IMP Lecture Hall None ANGELOPOULOU Eleni (Ellis), SCHAFFER Petra (Grade), RAMIREZ America (Köhler)Date: 2025-07-21, Time: 12:30:00, Speaker: ANGELOPOULOU Eleni (Ellis)SCHAFFER Petra (Grade)RAMIREZ America (Köhler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIMITRIADI Anna (Mendjan), LEITNER Moritz (Martinez), GAO Peng (Dagdas)Date: 2025-07-28, Time: 12:30:00, Speaker: DIMITRIADI Anna (Mendjan)LEITNER Moritz (Martinez)GAO Peng (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None LI Wenxin (Zimmer), FISCHER Felix (Zagrovic), ABESAMIS Kim Ivan (Dong)Date: 2025-08-04, Time: 12:30:00, Speaker: LI Wenxin (Zimmer)FISCHER Felix (Zagrovic)ABESAMIS Kim Ivan (Dong), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KLEIFELD Justus (Urban), MCATEER Tara (Pinheiro), BHATTACHARYA Mrinnanda (Zimmer)Date: 2025-08-11, Time: 12:30:00, Speaker: KLEIFELD Justus (Urban)MCATEER Tara (Pinheiro)BHATTACHARYA Mrinnanda (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BELL Lillie (Clausen), MIHAILOVIC Milica (Karagöz), GUYNES Keroshini (Jachowicz)Date: 2025-08-18, Time: 12:30:00, Speaker: BELL Lillie (Clausen)MIHAILOVIC Milica (Karagöz)GUYNES Keroshini (Jachowicz), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BOHL VIALLEFONT Gregoire (Nordborg), MARCHIORI Elisa (Van der Veeken), JAHNEL Stefan (Mendjan)Date: 2025-08-25, Time: 12:30:00, Speaker: BOHL VIALLEFONT Gregoire (Nordborg)MARCHIORI Elisa (Van der Veeken)JAHNEL Stefan (Mendjan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KIRCHGATTERER Paul (Gaidt), ACHLEITNER Sonja (Martens), KAYA Oguzhan (Knoblich)Date: 2025-09-01, Time: 12:30:00, Speaker: KIRCHGATTERER Paul (Gaidt)ACHLEITNER Sonja (Martens)KAYA Oguzhan (Knoblich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HUTH Michelle (Leeb), RADHAKRISHNA PILLAI Balashankar (Brennecke), REN Kaike (Otsuka)Date: 2025-09-08, Time: 12:30:00, Speaker: HUTH Michelle (Leeb)RADHAKRISHNA PILLAI Balashankar (Brennecke)REN Kaike (Otsuka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GONZALEZ ALVARADO Maria Nazareth (Grade), KASHKO Nataliia (Matos), OBERHUEMER Michael (Leeb)Date: 2025-09-15, Time: 12:30:00, Speaker: GONZALEZ ALVARADO Maria Nazareth (Grade)KASHKO Nataliia (Matos)OBERHUEMER Michael (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joao Matos, Peter Schlögelhofer Katja WassmannDate: 2025-09-18, Time: 11:00:00, Speaker: Katja Wassmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institute Jacques Monod, Host: Joao Matos, Peter Schlögelhofer
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KONSTANTINOU Andri (Obenauf), HARTMANN Felix (Matos), JENTOFT Ida (Pauli)Date: 2025-09-22, Time: 12:30:00, Speaker: KONSTANTINOU Andri (Obenauf)HARTMANN Felix (Matos)JENTOFT Ida (Pauli), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alex Stark Fabian TheisDate: 2025-09-25, Time: 11:00:00, Speaker: Fabian Theis, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Computational Health Center, Helmholtz Munich, Host: Alex Stark
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PAVLOVA Anzhela (Matos), SHARMA Sanskriti (Ellis), VETRANO Pamela (Ramundo)Date: 2025-09-29, Time: 12:30:00, Speaker: PAVLOVA Anzhela (Matos)SHARMA Sanskriti (Ellis)VETRANO Pamela (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WIGHARD Sara Sylvia (Burga), PRLESI Ines (Gerlich), BECHT Nanette (Gaidt)Date: 2025-10-06, Time: 12:30:00, Speaker: WIGHARD Sara Sylvia (Burga)PRLESI Ines (Gerlich)BECHT Nanette (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Elly Tanaka Alexander van OudenaardenDate: 2025-10-09, Time: 11:00:00, Speaker: Alexander van Oudenaarden, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Elly Tanaka
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PIECH Lucas (Leonard), NABIH MOSTAFA Amena (Pauli), GREMMELMAIER Constanze (Plaschka)Date: 2025-10-13, Time: 12:30:00, Speaker: PIECH Lucas (Leonard)NABIH MOSTAFA Amena (Pauli)GREMMELMAIER Constanze (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Andrea Pauli Anne BrunetDate: 2025-10-16, Time: 11:00:00, Speaker: Anne Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Stanford University, Host: Andrea Pauli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KYPRIANOU Christos (Rivron), MOYSIADOU Sofia (Obenauf), GALLAGE CHANUKA POSHITHA Fernando (Zimmer)Date: 2025-10-20, Time: 12:30:00, Speaker: KYPRIANOU Christos (Rivron)MOYSIADOU Sofia (Obenauf)GALLAGE CHANUKA POSHITHA Fernando (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz, Martin Leeb Aydan Bulut-KarsliogluDate: 2025-10-23, Time: 11:00:00, Speaker: Aydan Bulut-Karslioglu, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MPI Berlin, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
12:30 IMP Lecture Hall None LAROVENKO Svetlana (Brennecke), HIDAKA Takuya (Gerlich)Date: 2025-10-27, Time: 12:30:00, Speaker: LAROVENKO Svetlana (Brennecke)HIDAKA Takuya (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall David Haselbach Kresten Lindorff-LarssenDate: 2025-10-30, Time: 11:00:00, Speaker: Kresten Lindorff-Larssen, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: David Haselbach
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIAS Ana Beatriz (Slade), VALERI Erika (Gaidt), CHATZIANGELOU Myrto (Stark)Date: 2025-11-03, Time: 12:30:00, Speaker: DIAS Ana Beatriz (Slade)VALERI Erika (Gaidt)CHATZIANGELOU Myrto (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None FRASZ Lisa-Maria (Obenauf), MYLARSHCHIKOV Dmitry (Gerlich), SAHA Sayantan (Huis)Date: 2025-11-10, Time: 12:30:00, Speaker: FRASZ Lisa-Maria (Obenauf)MYLARSHCHIKOV Dmitry (Gerlich)SAHA Sayantan (Huis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz, Martin Leeb Jamie HackettDate: 2025-11-13, Time: 11:00:00, Speaker: Jamie Hackett, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: EMBL Rome, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PITASI Mattia (Leeb), FORBES Rebecca (Görke), MATURI Samuele (Grade)Date: 2025-11-17, Time: 12:30:00, Speaker: PITASI Mattia (Leeb)FORBES Rebecca (Görke)MATURI Samuele (Grade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
To be annouced
11:00 IMBA/GMI Lecture Hall Marco Hein Noam Stern-GinossarDate: 2025-11-20, Time: 11:00:00, Speaker: Noam Stern-Ginossar, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute of Science, Host: Marco Hein
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HEINZL Monika (Stark), MARTZIOS Panagiotis (Huis), BASTOS VENTURA Guilherme (Pinheiro)Date: 2025-11-24, Time: 12:30:00, Speaker: HEINZL Monika (Stark)MARTZIOS Panagiotis (Huis)BASTOS VENTURA Guilherme (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None JONASSON Mattias (Bücker), KNAUDT Hannah (Haselbach)Date: 2025-12-01, Time: 12:30:00, Speaker: JONASSON Mattias (Bücker)KNAUDT Hannah (Haselbach), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BERKUN Kathleen (Hallacli), , GRAF Max (Plaschka)Date: 2025-12-15, Time: 12:30:00, Speaker: BERKUN Kathleen (Hallacli)GRAF Max (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BOHAUMILITZKY Lena (Pinheiro), SPEICHERT Katarzyna (Martens), NG Hing Pan (Ma)Date: 2026-01-12, Time: 12:30:00, Speaker: BOHAUMILITZKY Lena (Pinheiro)SPEICHERT Katarzyna (Martens)NG Hing Pan (Ma), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None FARAWAY Rupert (Plaschka), ETHIER Elizabeth (Hallacli), RAINA Shiviya (Dammermann)Date: 2026-01-19, Time: 12:30:00, Speaker: FARAWAY Rupert (Plaschka)ETHIER Elizabeth (Hallacli)RAINA Shiviya (Dammermann), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WULF Paul Oliver (Tessmar), MISHRA Sachin (Stark), OGZUC Olivia (Querques)Date: 2026-01-26, Time: 12:30:00, Speaker: WULF Paul Oliver (Tessmar)MISHRA Sachin (Stark)OGZUC Olivia (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None COSTANTINI Elena (Tanaka), VIOHL Niklas (Köhler), LEON-RUIZ Jesus (Dolan)Date: 2026-02-02, Time: 12:30:00, Speaker: COSTANTINI Elena (Tanaka)VIOHL Niklas (Köhler)LEON-RUIZ Jesus (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None MIOCIC-STOSIC Fran (Zagrovic), BELL Caelan (Gerlich), KLEINWAECHTER Ava (Slade)Date: 2026-02-09, Time: 12:30:00, Speaker: MIOCIC-STOSIC Fran (Zagrovic)BELL Caelan (Gerlich)KLEINWAECHTER Ava (Slade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HOFMANN Maura (Van der Veeken), SEN Zeynep Begüm (Ma), ZEN PETISCO FIORE Ana Paula (Urban)Date: 2026-02-16, Time: 12:30:00, Speaker: HOFMANN Maura (Van der Veeken)SEN Zeynep Begüm (Ma)ZEN PETISCO FIORE Ana Paula (Urban), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None JANKOWSKA Julia (Ameres), DOCAVO GARCIA Antonio (Jachowicz), HAONAN Bao (Dolan)Date: 2026-02-23, Time: 12:30:00, Speaker: JANKOWSKA Julia (Ameres)DOCAVO GARCIA Antonio (Jachowicz)HAONAN Bao (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RUSSETT Colleen (Berger), ZEILER Christine (Kovarik), HOLLAUS David (Gaidt)Date: 2026-03-02, Time: 12:30:00, Speaker: RUSSETT Colleen (Berger)ZEILER Christine (Kovarik)HOLLAUS David (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GUZMAN PEREZ Sebastian (Martinez), ROFFAY Chloe (Pinheiro), BHARDWAJ Vishakha (Schlögelhofer)Date: 2026-03-09, Time: 12:30:00, Speaker: GUZMAN PEREZ Sebastian (Martinez)ROFFAY Chloe (Pinheiro)BHARDWAJ Vishakha (Schlögelhofer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
