Search Results

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans.

2022 PLOS GENET;18(4):e1010150.
PMID: 35442950

Holzer, Elisabeth; Rumpf-Kienzl, Cornelia; Falk, Sebastian; Dammermann, Alexander

Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry.

2022 Science Advances;8(7):eabl8861.
PMID: 35171669

Baudrimont, Antoine; Paouneskou, Dimitra; Mohammad, Ariz; Lichtenberger, Raffael; Blundon, Joshua; Kim, Yumi; Hartl, Markus; Falk, Sebastian; Schedl, Tim; Jantsch, Verena

Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans

2021 GENE DEV;35(17-18):1304-1323.
PMID: 34413138

Perez-Borrajero, Cecilia; Podvalnaya, Nadezda; Holleis, Kay; Lichtenberger, Raffael; Karaulanov, Emil; Simon, Bernd; Basquin, Jérôme; Hennig, Janosch; Ketting, René F; Falk, Sebastian

A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA.

2021 NUCLEIC ACIDS RES
PMID: 33877360

Cánovas-Márquez, José Tomás; Falk, Sebastian; Nicolás, Francisco E; Padmanabhan, Subramanian; Zapata-Pérez, Rubén; Sánchez-Ferrer, Álvaro; Navarro, Eusebio; Garre, Victoriano

In-depth interrogation of protein thermal unfolding data with MoltenProt.

2020 PROTEIN SCI
PMID: 33140490

Kotov, Vadim; Mlynek, Georg; Vesper, Oliver; Pletzer, Marina; Wald, Jiri; Teixeira-Duarte, Celso M; Celia, Herve; Garcia-Alai, Maria; Nussberger, Stephan; Buchanan, Susan K; Morais-Cabral, João H; Loew, Christian; Djinovic-Carugo, Kristina; Marlovits, Thomas C

Structural and antigenic investigation of Usutu virus envelope protein domain III.

2020 VIROLOGY;551:46-57.
PMID: 33011522

Schoenenwald, Amelie; Pletzer, Marina; Skern, Tim

To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome.

2020 COLD SPRING HARB SYM
PMID: 32493762

Lingaraju, Mahesh; Schuller, Jan M; Falk, Sebastian; Gerlach, Piotr; Bonneau, Fabien; Basquin, Jérôme; Benda, Christian; Conti, Elena

Purification and Reconstitution of the S. cerevisiae TRAMP and Ski Complexes for Biochemical and Structural Studies.

2020 Meth Mol Biol;2062:491-513.
PMID: 31768992

Keidel, Achim; Conti, Elena; Falk, Sebastian

The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

2019 NAT COMMUN
PMID: 31358741

Lingaraju, Mahesh; Johnsen, Dennis; Schlundt, Andreas; Langer, Lukas M.; Basquin, Jérôme; Sattler, Michael; Jensen, Torben Heick; Falk, Sebastian; Conti, Elena

Distinct and evolutionary conserved structural features of the human nuclear exosome complex.

2018 eLife;7
PMID: 30047866

Gerlach, Piotr; Schuller, Jan M; Bonneau, Fabien; Basquin, Jérôme; Reichelt, Peter; Falk, Sebastian; Conti, Elena

Structure of the nuclear exosome captured on a maturing preribosome.

2018 SCIENCE;360(6385):219-222.
PMID: 29519915

Schuller, Jan Michael; Falk, Sebastian; Fromm, Lisa; Hurt, Ed; Conti, Elena

Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome.

2017 NAT COMMUN;8(1):1787.
PMID: 29176610

Fromm, Lisa; Falk, Sebastian; Flemming, Dirk; Schuller, Jan Michael; Thoms, Matthias; Conti, Elena; Hurt, Ed

Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.

2017 RNA;23(12):1780-1787.
PMID: 28883156

Falk, Sebastian; Tants, Jan-Niklas; Basquin, Jerôme; Thoms, Matthias; Hurt, Ed; Sattler, Michael; Conti, Elena

Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase.

2017 Cell Rep;20(10):2279-2286.
PMID: 28877463

Falk, Sebastian; Bonneau, Fabien; Ebert, Judith; Kögel, Alexander; Conti, Elena

Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.

2016 NAT COMMUN;7:13573.
PMID: 27905398

Falk, Sebastian; Finogenova, Ksenia; Melko, Mireille; Benda, Christian; Lykke-Andersen, Søren; Jensen, Torben Heick; Conti, Elena

The conformational plasticity of eukaryotic RNA-dependent ATPases.

2015 FEBS J;282(5):850-63.
PMID: 25645110

Ozgur, Sevim; Buchwald, Gretel; Falk, Sebastian; Chakrabarti, Sutapa; Prabu, Jesuraj Rajan; Conti, Elena

The RNA helicase FRH is an ATP-dependent regulator of CK1a in the circadian clock of Neurospora crassa.

2014 NAT COMMUN;5:3598.
PMID: 24710172

Lauinger, Linda; Diernfellner, Axel; Falk, Sebastian; Brunner, Michael

The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.

2014 EMBO J;33(23):2829-46.
PMID: 25319414

Schuch, Benjamin; Feigenbutz, Monika; Makino, Debora L; Falk, Sebastian; Basquin, Claire; Mitchell, Phil; Conti, Elena

The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities.

2014 MOL CELL;55(6):856-867.
PMID: 25175027

Falk, Sebastian; Weir, John R; Hentschel, Jendrik; Reichelt, Peter; Bonneau, Fabien; Conti, Elena

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