Retinal regions shape human and murine Müller cell proteome profile and functionality.
Kaplan Lew, Drexler Corinne, Pfaller Anna M, Brenna Santra, Wunderlich Kirsten A, Dimitracopoulos Andrea, Merl-Pham Juliane, Perez Maria-Theresa, Schlötzer-Schrehardt Ursula, Enzmann Volker, Samardzija Marijana, Puig Berta, Fuchs Peter, Franze Kristian, Hauck Stefanie M, Grosche Antje
A Ca-Mediated Switch of Epiplakin from a Diffuse to Keratin-Bound State Affects Keratin Dynamics.
Ratajczyk Sonia, Drexler Corinne, Windoffer Reinhard, Leube Rudolf E, Fuchs Peter
Comparative genomics reveals evolutionary loss of epiplakin in cetaceans.
Fuchs Peter, Drexler Corinne, Ratajczyk Sonia, Eckhart Leopold
Functional and Genetic Analysis of Epiplakin in Epithelial Cells.
Szabo Sandra, Wögenstein Karl L, Fuchs Peter
Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.
Szabo Sandra, Wögenstein Karl L, Österreicher Christoph H, Guldiken Nurdan, Chen Yu, Doler Carina, Wiche Gerhard, Boor Peter, Haybaeck Johannes, Strnad Pavel, Fuchs Peter
Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules.
Wögenstein Karl L, Szabo Sandra, Lunova Mariia, Wiche Gerhard, Haybaeck Johannes, Strnad Pavel, Boor Peter, Wagner Martin, Fuchs Peter
Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-Ogna.
Walko Gernot, Vukasinovic Nevena, Gross Karin, Fischer Irmgard, Sibitz Sabrina, Fuchs Peter, Reipert Siegfried, Jungwirth Ute, Berger Walter, Salzer Ulrich, Carugo Oliviero, Castañón Maria J, Wiche Gerhard
Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity.
Fuchs Peter, Zörer Michael, Reipert Siegfried, Rezniczek Günther A, Propst Friedrich, Walko Gernot, Fischer Irmgard, Bauer Jan, Leschnik Michael W, Lüscher Bernhard, Thalhammer Johann G, Lassmann Hans, Wiche Gerhard
Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms.
Konieczny Patryk, Fuchs Peter, Reipert Siegfried, Kunz Wolfram S, Zeöld Anikó, Fischer Irmgard, Paulin Denise, Schröder Rolf, Wiche Gerhard
Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption.
Spazierer Daniel, Raberger Julia, Gross Karin, Fuchs Peter, Wiche Gerhard
Conditional targeting of plectin in prenatal and adult mouse stratified epithelia causes keratinocyte fragility and lesional epidermal barrier defects.
Ackerl Reinhard, Walko Gernot, Fuchs Peter, Fischer Irmgard, Schmuth Matthias, Wiche Gerhard
Plectin scaffolds recruit energy-controlling AMP-activated protein kinase (AMPK) in differentiated myofibres.
Gregor Martin, Zeöld Aniko, Oehler Susanne, Marobela Kerstin Andrä, Fuchs Peter, Weigel Günter, Hardie D Graham, Wiche Gerhard
Epiplakin is dispensable for skin barrier function and for integrity of keratin network cytoarchitecture in simple and stratified epithelia.
Spazierer Daniel, Fuchs Peter, Reipert Siegfried, Fischer Irmgard, Schmuth Matthias, Lassmann Hans, Wiche Gerhard
Plectin rodless isoform expression and its detection in mouse brain.
Fuchs Peter, Spazierer Daniel, Wiche Gerhard
Targeted ablation of plectin isoform 1 uncovers role of cytolinker proteins in leukocyte recruitment.
Abrahamsberg Christina, Fuchs Peter, Osmanagic-Myers Selma, Fischer Irmgard, Propst Friedrich, Elbe-Bürger Adelheid, Wiche Gerhard