MUT-7 exoribonuclease activity and localization are mediated by an ancient domain.
Busetto Virginia, Pshanichnaya Lizaveta, Lichtenberger Raffael, Hann Stephan, Ketting René F, Falk Sebastian
Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease.
Podvalnaya Nadezda, Bronkhorst Alfred W, Lichtenberger Raffael, Hellmann Svenja, Nischwitz Emily, Falk Torben, Karaulanov Emil, Butter Falk, Falk Sebastian, Ketting René F
piRNA processing by a trimeric Schlafen-domain nuclease.
Podvalnaya Nadezda, Bronkhorst Alfred W, Lichtenberger Raffael, Hellmann Svenja, Nischwitz Emily, Falk Torben, Karaulanov Emil, Butter Falk, Falk Sebastian, Ketting René F
A modified TurboID approach identifies tissue-specific centriolar components in C. elegans.
Holzer Elisabeth, Rumpf-Kienzl Cornelia, Falk Sebastian, Dammermann Alexander
Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry.
Baudrimont Antoine, Paouneskou Dimitra, Mohammad Ariz, Lichtenberger Raffael, Blundon Joshua, Kim Yumi, Hartl Markus, Falk Sebastian, Schedl Tim, Jantsch Verena
Structural basis of PETISCO complex assembly during piRNA biogenesis in .
Perez-Borrajero Cecilia, Podvalnaya Nadezda, Holleis Kay, Lichtenberger Raffael, Karaulanov Emil, Simon Bernd, Basquin Jérôme, Hennig Janosch, Ketting René F, Falk Sebastian
A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA.
Cánovas-Márquez José Tomás, Falk Sebastian, Nicolás Francisco E, Padmanabhan Subramanian, Zapata-Pérez Rubén, Sánchez-Ferrer Álvaro, Navarro Eusebio, Garre Victoriano
Purification and Reconstitution of the S. cerevisiae TRAMP and Ski Complexes for Biochemical and Structural Studies.
Keidel Achim, Conti Elena, Falk Sebastian
To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome.
Lingaraju Mahesh, Schuller Jan M, Falk Sebastian, Gerlach Piotr, Bonneau Fabien, Basquin Jérôme, Benda Christian, Conti Elena
The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.
Lingaraju Mahesh, Johnsen Dennis, Schlundt Andreas, Langer Lukas M, Basquin Jérôme, Sattler Michael, Heick Jensen Torben, Falk Sebastian, Conti Elena
Structure of the nuclear exosome captured on a maturing preribosome.
Schuller Jan Michael, Falk Sebastian, Fromm Lisa, Hurt Ed, Conti Elena
Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
Falk Sebastian, Tants Jan-Niklas, Basquin Jerôme, Thoms Matthias, Hurt Ed, Sattler Michael, Conti Elena
Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase.
Falk Sebastian, Bonneau Fabien, Ebert Judith, Kögel Alexander, Conti Elena
Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Falk Sebastian, Finogenova Ksenia, Melko Mireille, Benda Christian, Lykke-Andersen Søren, Jensen Torben Heick, Conti Elena
The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities.
Falk Sebastian, Weir John R, Hentschel Jendrik, Reichelt Peter, Bonneau Fabien, Conti Elena