Enhancer cooperativity can compensate for loss of activity over large genomic distances.
Thomas Henry F, Feng Songjie, Haslhofer Felix, Huber Marie, García Gallardo María, Loubiere Vincent, Vanina Daria, Pitasi Mattia, Stark Alexander, Buecker Christa
What is an enhancer?
Thomas Henry Fabian, Buecker Christa
Transient upregulation of IRF1 during exit from naive pluripotency confers viral protection.
Romeike Merrit, Spach Stephanie, Huber Marie, Feng Songjie, Vainorius Gintautas, Elling Ulrich, Versteeg Gjis A, Buecker Christa
NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation.
Huth Michelle, Santini Laura, Galimberti Elena, Ramesmayer Julia, Titz-Teixeira Fabian, Sehlke Robert, Oberhuemer Michael, Stummer Sarah, Herzog Veronika, Garmhausen Marius, Romeike Merrit, Chugunova Anastasia, Leesch Friederike, Holcik Laurenz, Weipoltshammer Klara, Lackner Andreas, Schoefer Christian, von Haeseler Arndt, Buecker Christa, Pauli Andrea, Ameres Stefan L, Smith Austin, Beyer Andreas, Leeb Martin
Science shines in a new virtual SY-Stem.
Buecker Christa, Merkle Florian T
Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements.
Thomas Henry F, Kotova Elena, Jayaram Swathi, Pilz Axel, Romeike Merrit, Lackner Andreas, Penz Thomas, Bock Christoph, Leeb Martin, Halbritter Florian, Wysocka Joanna, Buecker Christa
Reorganization of enhancer patterns in transition from naive to primed pluripotency.
Buecker Christa, Srinivasan Rajini, Wu Zhixiang, Calo Eliezer, Acampora Dario, Faial Tiago, Simeone Antonio, Tan Minjia, Swigut Tomasz, Wysocka Joanna
Enhancers as information integration hubs in development: lessons from genomics.
Buecker Christa, Wysocka Joanna
A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.
Buecker Christa, Chen Hsu-Hsin, Polo Jose Maria, Daheron Laurence, Bu Lei, Barakat Tahsin Stefan, Okwieka Patricia, Porter Andrew, Gribnau Joost, Hochedlinger Konrad, Geijsen Niels