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Processing and Visualization of Protec-Seq Data for the Generation of Calibrated, Genome-Wide Double Double-Strand Break (dDSB) Maps.

2025 Methods in molecular biology (Clifton, N.J.);2856:401, 418, 401-418.
PMID:  39283465

Chen Doris, Xaver Martin, Klein Franz

Physical interaction with Spo11 mediates the localisation of Mre11 to chromatin in meiosis and promotes its nuclease activity.

2024 Nucleic acids research;52(8):4328, 4343, 4328-4343.
PMID:  38407383

Aithal Rakesh, Nangalia Kuldeep, Spirek Mario, Chen Doris, Klein Franz, Krejci Lumir

Spo11 generates gaps through concerted cuts at sites of topological stress.

2021 Nature;594(7864):577, 582, 577-582.
PMID:  34108684

Prieler Silvia, Chen Doris, Huang Lingzhi, Mayrhofer Elisa, Zsótér Soma, Vesely Magdalena, Mbogning Jean, Klein Franz

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation.

2020 Proceedings of the National Academy of Sciences of the United States of America;117(48):30577, 30588, 30577-30588.
PMID:  33199619

Sanchez Aurore, Adam Céline, Rauh Felix, Duroc Yann, Ranjha Lepakshi, Lombard Bérangère, Mu Xiaojing, Wintrebert Mélody, Loew Damarys, Guarné Alba, Gnan Stefano, Chen Chun-Long, Keeney Scott, Cejka Petr, Guérois Raphaël, Klein Franz, Charbonnier Jean-Baptiste, Borde Valérie

Meiosis-specific prophase-like pathway controls cleavage-independent release of cohesin by Wapl phosphorylation.

2019 PLoS genetics;15(1):e1007851.
PMID:  30605471

Challa Kiran, Fajish V Ghanim, Shinohara Miki, Klein Franz, Gasser Susan M, Shinohara Akira

Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation.

2018 The Journal of cell biology;217(10):3398, 3415, 3398-3415.
PMID:  30037925

Karányi Zsolt, Halász László, Acquaviva Laurent, Jónás Dávid, Hetey Szabolcs, Boros-Oláh Beáta, Peng Feng, Chen Doris, Klein Franz, Géli Vincent, Székvölgyi Lóránt

Transcription dynamically patterns the meiotic chromosome-axis interface.

2015 eLife;4
PMID:  26258962

Sun Xiaoji, Huang Lingzhi, Markowitz Tovah E, Blitzblau Hannah G, Chen Doris, Klein Franz, Hochwagen Andreas

Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis.

2013 PLoS genetics;9(12):e1004067.
PMID:  24385936

Xaver Martin, Huang Lingzhi, Chen Doris, Klein Franz

Spo11-accessory proteins link double-strand break sites to the chromosome axis in early meiotic recombination.

2011 Cell;146(3):372, 383, 372-83.
PMID:  21816273

Panizza Silvia, Mendoza Marco A, Berlinger Marc, Huang Lingzhi, Nicolas Alain, Shirahige Katsuhiko, Klein Franz

Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans.

2010 PLoS genetics;6(11):e1001219.
PMID:  21124819

Baudrimont Antoine, Penkner Alexandra, Woglar Alexander, Machacek Thomas, Wegrostek Christina, Gloggnitzer Jiradet, Fridkin Alexandra, Klein Franz, Gruenbaum Yosef, Pasierbek Pawel, Jantsch Verena

Analysis of protein-DNA interactions during meiosis by quantitative chromatin immunoprecipitation (qChIP).

2009 Methods in molecular biology (Clifton, N.J.);557:267, 283, 267-83.
PMID:  19799188

Mendoza Marco Antonio, Panizza Silvia, Klein Franz

A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene.

2007 The EMBO journal;26(24):5061, 5070, 5061-70.
PMID:  18007598

Uanschou Clemens, Siwiec Tanja, Pedrosa-Harand Andrea, Kerzendorfer Claudia, Sanchez-Moran Eugenio, Novatchkova Maria, Akimcheva Svetlana, Woglar Alexander, Klein Franz, Schlögelhofer Peter

Mnd2, an essential antagonist of the anaphase-promoting complex during meiotic prophase.

2005 Cell;120(6):789, 801, 789-801.
PMID:  15797380

Penkner Alexandra M, Prinz Susanne, Ferscha Stefan, Klein Franz

The control of Spo11's interaction with meiotic recombination hotspots.

2005 Genes & development;19(2):255, 269, 255-69.
PMID:  15655113

Prieler Silvia, Penkner Alexandra, Borde Valérie, Klein Franz

Mnd1 is required for meiotic interhomolog repair.

2004 Current biology : CB;14(9):752, 762, 752-62.
PMID:  15120066

Zierhut Christian, Berlinger Marc, Rupp Christian, Shinohara Akira, Klein Franz

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