Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Ehrmann Julian F, Grabarczyk Daniel B, Heinke Maria, Deszcz Luiza, Kurzbauer Robert, Hudecz Otto, Shulkina Alexandra, Gogova Rebeca, Meinhart Anton, Versteeg Gijs A, Clausen Tim
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
de Almeida Melanie, Hinterndorfer Matthias, Brunner Hanna, Grishkovskaya Irina, Singh Kashish, Schleiffer Alexander, Jude Julian, Deswal Sumit, Kalis Robert, Vunjak Milica, Lendl Thomas, Imre Richard, Roitinger Elisabeth, Neumann Tobias, Kandolf Susanne, Schutzbier Michael, Mechtler Karl, Versteeg Gijs A, Haselbach David, Zuber Johannes
Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner.
Watzenboeck Martin L, Drobits Barbara, Zahalka Sophie, Gorki Anna-Dorothea, Farhat Asma, Quattrone Federica, Hladik Anastasiya, Lakovits Karin, Richard Gabriel M, Lederer Therese, Strobl Birgit, Versteeg Gijs A, Boon Louis, Starkl Philipp, Knapp Sylvia
Negative Regulation of the Innate Immune Response through Proteasomal Degradation and Deubiquitination.
Budroni Valentina, Versteeg Gijs A
A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52.
Hacker Kathrin, Benke Stefan, Agerer Benedikt, Scinicariello Sara, Budroni Valentina, Versteeg Gijs A
TRIM proteins.
Vunjak Milica, Versteeg Gijs A
Human tripartite motif protein 52 is required for cell context-dependent proliferation.
Benke Stefan, Agerer Benedikt, Haas Lisa, Stöger Martin, Lercher Alexander, Gabler Lisa, Kiss Izabella, Scinicariello Sara, Berger Walter, Bergthaler Andreas, Obenauf Anna C, Versteeg Gijs A
Ubiquitin enzymes in the regulation of immune responses.
Ebner Petra, Versteeg Gijs A, Ikeda Fumiyo
Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.
Shi Mude, Cho Hyelim, Inn Kyung-Soo, Yang Aerin, Zhao Zhen, Liang Qiming, Versteeg Gijs A, Amini-Bavil-Olyaee Samad, Wong Lai-Yee, Zlokovic Berislav V, Park Hee-Sung, García-Sastre Adolfo, Jung Jae U
InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins.
Versteeg Gijs A, Benke Stefan, García-Sastre Adolfo, Rajsbaum Ricardo
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Rajsbaum Ricardo, Versteeg Gijs A, Schmid Sonja, Maestre Ana M, Belicha-Villanueva Alan, Martínez-Romero Carles, Patel Jenish R, Morrison Juliet, Pisanelli Giuseppe, Miorin Lisa, Laurent-Rolle Maudry, Moulton Hong M, Stein David A, Fernandez-Sesma Ana, tenOever Benjamin R, García-Sastre Adolfo
TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity.
Rajsbaum Ricardo, García-Sastre Adolfo, Versteeg Gijs A
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.
Versteeg Gijs A, Rajsbaum Ricardo, Sánchez-Aparicio Maria Teresa, Maestre Ana M, Valdiviezo Julio, Shi Mude, Inn Kyung-Soo, Fernandez-Sesma Ana, Jung Jae, García-Sastre Adolfo
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.
Mata Miguel A, Satterly Neal, Versteeg Gijs A, Frantz Doug, Wei Shuguang, Williams Noelle, Schmolke Mirco, Peña-Llopis Samuel, Brugarolas James, Forst Christian V, White Michael A, García-Sastre Adolfo, Roth Michael G, Fontoura Beatriz M A