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Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase.

2023 Structure (London, England : 1993);31(4):435, 446.e4, 435-446.e4.
PMID:  36854301

Truebestein Linda, Antonioli Sumire, Waltenberger Elisabeth, Gehin Charlotte, Gavin Anne-Claude, Leonard Thomas A

Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging.

2023 Nature methods(3)
PMID:  36823335

Fu Shuang, Shi Wei, Luo Tingdan, He Yingchuan, Zhou Lulu, Yang Jie, Yang Zhichao, Liu Jiadong, Liu Xiaotian, Guo Zhiyong, Yang Chengyu, Liu Chao, Huang Zhen-Li, Ries Jonas, Zhang Mingjie, Xi Peng, Jin Dayong, Li Yiming

Modeling the genetic footprint of fluctuating balancing selection: from the local to the genomic scale.

2023 Genetics;223(4)
PMID:  36790814

Wittmann Meike J, Mousset Sylvain, Hermisson Joachim

Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and autophagy.

2023 The EMBO journal;42(10):e112053.
PMID:  36762703

Picchianti Lorenzo, Sánchez de Medina Hernández Víctor, Zhan Ni, Irwin Nicholas At, Groh Roan, Stephani Madlen, Hornegger Harald, Beveridge Rebecca, Sawa-Makarska Justyna, Lendl Thomas, Grujic Nenad, Naumann Christin, Martens Sascha, Richards Thomas A, Clausen Tim, Ramundo Silvia, Karagöz G Elif, Dagdas Yasin

ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1.

2023 Structure (London, England : 1993);31(3):343, 354.e3, 343-354.e3.
PMID:  36758543

Shaw Alexandria L, Parson Matthew A H, Truebestein Linda, Jenkins Meredith L, Leonard Thomas A, Burke John E

Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.

2023 Science (New York, N.Y.);379(6637):1117, 1123, 1117-1123.
PMID:  36758105

Ehrmann Julian F, Grabarczyk Daniel B, Heinke Maria, Deszcz Luiza, Kurzbauer Robert, Hudecz Otto, Shulkina Alexandra, Gogova Rebeca, Meinhart Anton, Versteeg Gijs A, Clausen Tim

SLAMseq resolves the kinetics of maternal and zygotic gene expression during early zebrafish embryogenesis.

2023 Cell reports;42(2):112070.
PMID:  36757845

Bhat Pooja, Cabrera-Quio Luis E, Herzog Veronika A, Fasching Nina, Pauli Andrea, Ameres Stefan L

PKD autoinhibition in regulates activation loop autophosphorylation in .

2023 Proceedings of the National Academy of Sciences of the United States of America;120(7):e2212909120.
PMID:  36745811

Reinhardt Ronja, Hirzel Kai, Link Gisela, Eisler Stephan A, Hägele Tanja, Parson Matthew A H, Burke John E, Hausser Angelika, Leonard Thomas A

PlantACT! - how to tackle the climate crisis.

2023 Trends in plant science;28(5):537, 543, 537-543.
PMID:  36740490

Hirt Heribert, Al-Babili Salim, Almeida-Trapp Marilia, Martin Antoine, Aranda Manuel, Bartels Dorothea, Bennett Malcolm, Blilou Ikram, Boer Damian, Boulouis Alix, Bowler Chris, Brunel-Muguet Sophie, Chardon Fabien, Colcombet Jean, Colot Vincent, Daszkowska-Golec Agata, Dinneny Jose R, Field Ben, Froehlich Katja, Gardener Catherine H, Gojon Alain, Gomès Eric, Gomez-Alvarez Eva María, Gutierrez Crisanto, Havaux Michel, Hayes Scott, Heard Edith, Hodges Michael, Alghamdi Amal Khalaf, Laplaze Laurent, Lauersen Kyle J, Leonhardt Nathalie, Johnson Xenie, Jones Jonathan, Kollist Hannes, Kopriva Stanislav, Krapp Anne, Masson Mauricio Lopez-Portillo, McCabe Matthew F, Merendino Livia, Molina Antonio, Moreno Ramirez Jose L, Mueller-Roeber Bernd, Nicolas Michael, Nir Ido, Orduna Izamar Olivas, Pardo Jose M, Reichheld Jean-Philippe, Rodriguez Pedro L, Rouached Hatem, Saad Maged M, Schlögelhofer Peter, Singh Kirti A, De Smet Ive, Stanschewski Clara, Stra Alice, Tester Mark, Walsh Catherine, Weber Andreas P M, Weigel Detlef, Wigge Philip, Wrzaczek Michael, Wulff Brande B H, Young Iain M

Clathrin coats partially preassemble and subsequently bend during endocytosis.

2023 The Journal of cell biology(3)
PMID:  36734980

Mund Markus, Tschanz Aline, Wu Yu-Le, Frey Felix, Mehl Johanna L, Kaksonen Marko, Avinoam Ori, Schwarz Ulrich S, Ries Jonas

Effect of ATG12-ATG5-ATG16L1 autophagy E3-like complex on the ability of LC3/GABARAP proteins to induce vesicle tethering and fusion.

2023 Cellular and molecular life sciences : CMLS;80(2):56.
PMID:  36729310

Iriondo Marina N, Etxaniz Asier, Varela Yaiza R, Ballesteros Uxue, Lázaro Melisa, Valle Mikel, Fracchiolla Dorotea, Martens Sascha, Montes L Ruth, Goñi Félix M, Alonso Alicia

Nanoscale structural organization and stoichiometry of the budding yeast kinetochore.

2023 The Journal of cell biology(4)
PMID:  36705601

Cieslinski Konstanty, Wu Yu-Le, Nechyporenko Lisa, Hörner Sarah Janice, Conti Duccio, Skruzny Michal, Ries Jonas

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.

2023 Nature communications;14(1):166.
PMID:  36631525

Appel Lisa-Marie, Franke Vedran, Benedum Johannes, Grishkovskaya Irina, Strobl Xué, Polyansky Anton, Ammann Gregor, Platzer Sebastian, Neudolt Andrea, Wunder Anna, Walch Lena, Kaiser Stefanie, Zagrovic Bojan, Djinovic-Carugo Kristina, Akalin Altuna, Slade Dea

Coding From Binding? Molecular Interactions at the Heart of Translation.

2023 Annual review of biophysics;52:69, 89, 69-89.
PMID:  36626765

Zagrovic Bojan, Adlhart Marlene, Kapral Thomas H

Proline and glucose metabolic reprogramming supports vascular endothelial and medial biomass in pulmonary arterial hypertension.

2023 JCI insight;8(4)
PMID:  36626231

Wertheim Bradley M, Wang Rui-Sheng, Guillermier Christelle, Hütter Christiane Vr, Oldham William M, Menche Jörg, Steinhauser Matthew L, Maron Bradley A

A quantitative map of nuclear pore assembly reveals two distinct mechanisms.

2023 Nature;613(7944):575, 581, 575-581.
PMID:  36599981

Otsuka Shotaro, Tempkin Jeremy O B, Zhang Wanlu, Politi Antonio Z, Rybina Arina, Hossain M Julius, Kueblbeck Moritz, Callegari Andrea, Koch Birgit, Morero Natalia Rosalia, Sali Andrej, Ellenberg Jan

Adaptation to high rates of chromosomal instability and aneuploidy through multiple pathways in budding yeast.

2023 The EMBO journal;42(8):e111500.
PMID:  36530167

Clarke Matthew N, Marsoner Theodor, Adell Manuel Alonso Y, Ravichandran Madhwesh C, Campbell Christopher S

Maximum-likelihood model fitting for quantitative analysis of SMLM data.

2023 Nature methods(1)
PMID:  36522500

Wu Yu-Le, Hoess Philipp, Tschanz Aline, Matti Ulf, Mund Markus, Ries Jonas

Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization.

2023 The Journal of cell biology;222(2)
PMID:  36515990

King Grant A, Wettstein Rahel, Varberg Joseph M, Chetlapalli Keerthana, Walsh Madison E, Gillet Ludovic C J, Hernández-Armenta Claudia, Beltrao Pedro, Aebersold Ruedi, Jaspersen Sue L, Matos Joao, Ünal Elçin

NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy.

2023 The EMBO journal;42(5):e111372.
PMID:  36514953

Kataura Tetsushi, Otten Elsje G, Rabanal-Ruiz Yoana, Adriaenssens Elias, Urselli Francesca, Scialo Filippo, Fan Lanyu, Smith Graham R, Dawson William M, Chen Xingxiang, Yue Wyatt W, Bronowska Agnieszka K, Carroll Bernadette, Martens Sascha, Lazarou Michael, Korolchuk Viktor I

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