Synthesis of a C-methylene-labeled isoleucine precursor as a useful tool for studying protein side-chain interactions and dynamics.
Höfurthner Theresa, Toscano Giorgia, Kontaxis Georg, Beier Andreas, Mayer Moriz, Geist Leonhard, McConnell Darryl B, Weinstabl Harald, Lichtenecker Roman, Konrat Robert
Synthesis of Novel cis-2-Azetidinones from imines and aclychloride using triethylamine.
Can Sakarya Handan, Ketrez Aslı
Sequestration of translation initiation factors in p62 condensates.
Danieli Alberto, Vucak Georg, Baccarini Manuela, Martens Sascha
Harnessing PROTAC technology to combat stress hormone receptor activation.
Gazorpak Mahshid, Hugentobler Karina M, Paul Dominique, Germain Pierre-Luc, Kretschmer Miriam, Ivanova Iryna, Frei Selina, Mathis Kei, Rudolf Remo, Mompart Barrenechea Sergio, Fischer Vincent, Xue Xiaohan, Ptaszek Aleksandra L, Holzinger Julian, Privitera Mattia, Hierlemann Andreas, Meijer Onno C, Konrat Robert, Carreira Erick M, Bohacek Johannes, Gapp Katharina
The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum Johannes, Franke Vedran, Appel Lisa-Marie, Walch Lena, Bruno Melania, Schneeweiss Rebecca, Gruber Juliane, Oberndorfer Helena, Frank Emma, Strobl Xué, Polyansky Anton, Zagrovic Bojan, Akalin Altuna, Slade Dea
Universal inverse modelling of point spread functions for SMLM localization and microscope characterization.
Liu Sheng, Chen Jianwei, Hellgoth Jonas, Müller Lucas-Raphael, Ferdman Boris, Karras Christian, Xiao Dafei, Lidke Keith A, Heintzmann Rainer, Shechtman Yoav, Li Yiming, Ries Jonas
Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes.
Fischer Katrin, Bradlerova Michaela, Decker Thomas, Supper Verena
Sec8 specifically interacts with the PDZ2 domain of synapse associated protein 102 (SAP102).
Korbula Katharina, Hammerschmid Iana, Lesigang Johannes, Dong Gang
The interplay of nuclear pores and lipids.
Stankunas Edvinas, Köhler Alwin
Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.
Sunshine Sara, Puschnik Andreas S, Replogle Joseph M, Laurie Matthew T, Liu Jamin, Zha Beth Shoshana, Nuñez James K, Byrum Janie R, McMorrow Aidan H, Frieman Matthew B, Winkler Juliane, Qiu Xiaojie, Rosenberg Oren S, Leonetti Manuel D, Ye Chun Jimmie, Weissman Jonathan S, DeRisi Joseph L, Hein Marco Y
piRNA processing by a trimeric Schlafen-domain nuclease.
Podvalnaya Nadezda, Bronkhorst Alfred W, Lichtenberger Raffael, Hellmann Svenja, Nischwitz Emily, Falk Torben, Karaulanov Emil, Butter Falk, Falk Sebastian, Ketting René F
Simulating structurally variable nuclear pore complexes for microscopy.
Theiss Maria, Hériché Jean-Karim, Russell Craig, Helekal David, Soppitt Alisdair, Ries Jonas, Ellenberg Jan, Brazma Alvis, Uhlmann Virginie
Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II.
Flores-Solis David, Lushpinskaia Irina P, Polyansky Anton A, Changiarath Arya, Boehning Marc, Mirkovic Milana, Walshe James, Pietrek Lisa M, Cramer Patrick, Stelzl Lukas S, Zagrovic Bojan, Zweckstetter Markus
Characterisation of TbSmee1 suggests endocytosis allows surface-bound cargo to enter the trypanosome flagellar pocket.
Schichler Daja, Konle Antonia, Spath Eva-Maria, Riegler Sina, Klein Alexandra, Seleznev Anna, Jung Sisco, Wuppermann Timothy, Wetterich Noah, Borges Alyssa, Meyer-Natus Elisabeth, Havlicek Katharina, Pérez Cabrera Sonia, Niedermüller Korbinian, Sajko Sara, Dohn Maximilian, Malzer Xenia, Riemer Emily, Tumurbaatar Tuguldur, Djinovic-Carugo Kristina, Dong Gang, Janzen Christian J, Morriswood Brooke
Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling.
Harding Olivia, Holzer Elisabeth, Riley Julia F, Martens Sascha, Holzbaur Erika L F
Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model.
Horánszky Alex, Shashikadze Bachuki, Elkhateib Radwa, Lombardo Salvo Danilo, Lamberto Federica, Zana Melinda, Menche Jörg, Fröhlich Thomas, Dinnyés András
AutoCore: A network-based definition of the core module of human autoimmunity and autoinflammation.
Guthrie Julia, Köstel Bal Sevgi, Lombardo Salvo Danilo, Müller Felix, Sin Celine, Hütter Christiane V R, Menche Jörg, Boztug Kaan
Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex.
Jaksch Dhaarsini, Irnstorfer Johanna, Kalman Petra-Franziska, Martinez Javier
Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Rasool Reyaz Ur, O'Connor Caitlin M, Das Chandan Kanta, Alhusayan Mohammed, Verma Brijesh Kumar, Islam Sehbanul, Frohner Ingrid E, Deng Qu, Mitchell-Velasquez Erick, Sangodkar Jaya, Ahmed Aqila, Linauer Sarah, Mudrak Ingrid, Rainey Jessica, Zawacki Kaitlin P, Suhan Tahra K, Callahan Catherine G, Rebernick Ryan, Natesan Ramakrishnan, Siddiqui Javed, Sauter Guido, Thomas Dafydd, Wang Shaomeng, Taylor Derek J, Simon Ronald, Cieslik Marcin, Chinnaiyan Arul M, Busino Luca, Ogris Egon, Narla Goutham, Asangani Irfan A
Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet.
Meyenberg Mathilde, Hakobyan Anna, Papac-Milicevic Nikolina, Göderle Laura, Langner Franziska L, Markovic Mateo, Lee Ji-Hyun, Koo Bon-Kyoung, Busslinger Georg A, da Silva Israel Tojal, Binder Christoph J, Menche Jörg, Loizou Joanna I