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Aged-vascular niche hinders osteogenesis of mesenchymal stem cells through paracrine repression of Wnt-axis.

2024 Aging cell;23(6):e14139.
PMID:  38578073

Fleischhacker Viviane, Milosic Filip, Bricelj Marko, Kührer Kristina, Wahl-Figlash Katharina, Heimel Patrick, Diendorfer Andreas, Nardini Eleonora, Fischer Irmgard, Stangl Herbert, Pietschmann Peter, Hackl Matthias, Foisner Roland, Grillari Johannes, Hengstschläger Markus, Osmanagic-Myers Selma

Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation.

2024 The Journal of cell biology;223(7)
PMID:  38573225

Baumann Verena, Achleitner Sonja, Tulli Susanna, Schuschnig Martina, Klune Lara, Martens Sascha

A set of cross-correlated relaxation experiments to probe the correlation time of two different and complementary spin pairs.

2024 Journal of magnetic resonance (San Diego, Calif. : 1997);361:107661.
PMID:  38547550

Ceccolini Irene, Kauffmann Clemens, Holzinger Julian, Konrat Robert, Zawadzka-Kazimierczuk Anna

Decorating phenylalanine side-chains with triple labeled C/F/H isotope patterns.

2024 Journal of biomolecular NMR;78(3):139, 147, 139-147.
PMID:  38509441

Toscano Giorgia, Holzinger Julian, Nagl Benjamin, Kontaxis Georg, Kählig Hanspeter, Konrat Robert, Lichtenecker Roman J

Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.

2024 bioRxiv : the preprint server for biology
PMID:  38496508

Nazeen Sumaiya, Wang Xinyuan, Zielinski Dina, Lam Isabel, Hallacli Erinc, Xu Ping, Ethier Elizabeth, Strom Ronya, Zanella Camila A, Nithianandam Vanitha, Ritter Dylan, Henderson Alexander, Saurat Nathalie, Afroz Jalwa, Nutter-Upham Andrew, Benyamini Hadar, Copty Joseph, Ravishankar Shyamsundar, Morrow Autumn, Mitchel Jonathan, Neavin Drew, Gupta Renuka, Farbehi Nona, Grundman Jennifer, Myers Richard H, Scherzer Clemens R, Trojanowski John Q, Van Deerlin Vivianna M, Cooper Antony A, Lee Edward B, Erlich Yaniv, Lindquist Susan, Peng Jian, Geschwind Daniel H, Powell Joseph, Studer Lorenz, Feany Mel B, Sunyaev Shamil R, Khurana Vikram

Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency.

2024 Molecular cell;84(8):1406, 1421.e8, 1406-1421.e8.
PMID:  38490199

Lando David, Ma Xiaoyan, Cao Yang, Jartseva Aleksandra, Stevens Tim J, Boucher Wayne, Reynolds Nicola, Montibus Bertille, Hall Dominic, Lackner Andreas, Ragheb Ramy, Leeb Martin, Hendrich Brian D, Laue Ernest D

Bacterial Lactonases ZenA with Noncanonical Structural Features Hydrolyze the Mycotoxin Zearalenone.

2024 ACS catalysis;14(5):3392, 3410, 3392-3410.
PMID:  38449531

Fruhauf Sebastian, Pühringer Dominic, Thamhesl Michaela, Fajtl Patricia, Kunz-Vekiru Elisavet, Höbartner-Gussl Andreas, Schatzmayr Gerd, Adam Gerhard, Damborsky Jiri, Djinovic-Carugo Kristina, Prokop Zbynek, Moll Wulf-Dieter

Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8 T cells.

2024 Cell reports;43(3):113853.
PMID:  38421875

Kamnev Anton, Mehta Tanvi, Wielscher Matthias, Chaves Beatriz, Lacouture Claire, Mautner Anna-Katharina, Shaw Lisa E, Caldera Michael, Menche Jörg, Weninger Wolfgang P, Farlik Matthias, Boztug Kaan, Dupré Loïc

Physical interaction with Spo11 mediates the localisation of Mre11 to chromatin in meiosis and promotes its nuclease activity.

2024 Nucleic acids research;52(8):4328, 4343, 4328-4343.
PMID:  38407383

Aithal Rakesh, Nangalia Kuldeep, Spirek Mario, Chen Doris, Klein Franz, Krejci Lumir

The Role of ATG9 Vesicles in Autophagosome Biogenesis.

2024 Journal of molecular biology;436(15):168489.
PMID:  38342428

Holzer Elisabeth, Martens Sascha, Tulli Susanna

Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons.

2024 Science advances(6)
PMID:  38335281

Santhosh Kumar Saranya, Naseri Nima N, Pather Sarshan R, Hallacli Erinc, Ndayisaba Alain, Buenaventura Chris, Acosta Karen, Roof Jennifer, Fazelinia Hossein, Spruce Lynn A, Luk Kelvin, Khurana Vikram, Rhoades Elizabeth, Shalem Ophir

Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tail.

2024 Bioorganic & medicinal chemistry;100:117617.
PMID:  38306881

Vogl Dominik P, Mateos Borja, Migotti Mario, Felkl Manuel, Conibear Anne C, Konrat Robert, Becker Christian F W

Cβ-Valine and Cγ-Leucine Methine Labeling To Probe Protein Ligand Interaction.

2024 Chembiochem : a European journal of chemical biology;25(6):e202300762.
PMID:  38294275

Toscano Giorgia, Höfurthner Theresa, Nagl Benjamin, Beier Andreas, Mayer Moriz, Geist Leonhard, McConnell Darryl B, Weinstabl Harald, Konrat Robert, Lichtenecker Roman J

N-methyladenosine in 5' UTR does not promote translation initiation.

2024 Molecular cell;84(3):584, 595.e6, 584-595.e6.
PMID:  38244546

Guca Ewelina, Alarcon Rodrigo, Palo Michael Z, Santos Leonardo, Alonso-Gil Santiago, Davyt Marcos, de Lima Leonardo H F, Boissier Fanny, Das Sarada, Zagrovic Bojan, Puglisi Joseph D, Hashem Yaser, Ignatova Zoya

Sculpting nuclear envelope identity from the endoplasmic reticulum during the cell cycle.

2024 Nucleus (Austin, Tex.);15(1):2299632.
PMID:  38238284

Deolal Pallavi, Scholz Julia, Ren Kaike, Bragulat-Teixidor Helena, Otsuka Shotaro

Evaluation of 5'-End Phosphorylation for Small RNA Stability and Target Regulation In Vivo.

2024 Methods in molecular biology (Clifton, N.J.);2741:255, 272, 255-272.
PMID:  38217658

Schilder Alexandra, Göpel Yvonne, Khan Muna Ayesha, Görke Boris

Optimal C NMR investigation of intrinsically disordered proteins at 1.2 GHz.

2024 Nature protocols;19(2):406, 440, 406-440.
PMID:  38087081

Schiavina Marco, Bracaglia Lorenzo, Rodella Maria Anna, Kümmerle Rainer, Konrat Robert, Felli Isabella C, Pierattelli Roberta

DNA on the move: mechanisms, functions and applications of transposable elements.

2024 FEBS open bio;14(1):13, 22, 13-22.
PMID:  38041553

Schmitz Michael, Querques Irma

Ligand H NMR Chemical Shifts as Accurate Reporters for Protein-Ligand Binding Interfaces in Solution.

2024 Chemphyschem : a European journal of chemical physics and physical chemistry;25(1):e202300636.
PMID:  37955910

Platzer Gerald, Ptaszek Aleksandra L, Böttcher Jark, Fuchs Julian E, Geist Leonhard, Braun Daniel, McConnell Darryl B, Konrat Robert, Sánchez-Murcia Pedro A, Mayer Moriz

All Light, Everywhere? Photoreceptors at Nonconventional Sites.

2024 Physiology (Bethesda, Md.);39(1)
PMID:  37905983

Mat Audrey, Vu Hong Ha, Wolf Eva, Tessmar-Raible Kristin

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