Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Falk Sebastian, Finogenova Ksenia, Melko Mireille, Benda Christian, Lykke-Andersen Søren, Jensen Torben Heick, Conti Elena
Discovery of methylfarnesoate as the annelid brain hormone reveals an ancient role of sesquiterpenoids in reproduction.
Schenk Sven, Krauditsch Christian, Frühauf Peter, Gerner Christopher, Raible Florian
No ATG8s, no problem? How LC3/GABARAP proteins contribute to autophagy.
Martens Sascha
Mechanism of cargo-directed Atg8 conjugation during selective autophagy.
Fracchiolla Dorotea, Sawa-Makarska Justyna, Zens Bettina, Ruiter Anita de, Zaffagnini Gabriele, Brezovich Andrea, Romanov Julia, Runggatscher Kathrin, Kraft Claudine, Zagrovic Bojan, Martens Sascha
SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation.
Kaufmann Tanja, Kukolj Eva, Brachner Andreas, Beltzung Etienne, Bruno Melania, Kostrhon Sebastian, Opravil Susanne, Hudecz Otto, Mechtler Karl, Warren Graham, Slade Dea
The genomic basis of circadian and circalunar timing adaptations in a midge.
Kaiser Tobias S, Poehn Birgit, Szkiba David, Preussner Marco, Sedlazeck Fritz J, Zrim Alexander, Neumann Tobias, Nguyen Lam-Tung, Betancourt Andrea J, Hummel Thomas, Vogel Heiko, Dorner Silke, Heyd Florian, von Haeseler Arndt, Tessmar-Raible Kristin
Genetic and mechanistic diversity of piRNA 3'-end formation.
Hayashi Rippei, Schnabl Jakob, Handler Dominik, Mohn Fabio, Ameres Stefan L, Brennecke Julius
STAT1 regulates marginal zone B cell differentiation in response to inflammation and infection with blood-borne bacteria.
Chen Ting-Ting, Tsai Ming-Hsun, Kung John T, Lin Kuo-I, Decker Thomas, Lee Chien-Kuo
Rapid movement and transcriptional re-localization of human cohesin on DNA.
Davidson Iain F, Goetz Daniela, Zaczek Maciej P, Molodtsov Maxim I, Huis In 't Veld Pim J, Weissmann Florian, Litos Gabriele, Cisneros David A, Ocampo-Hafalla Maria, Ladurner Rene, Uhlmann Frank, Vaziri Alipasha, Peters Jan-Michael
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins Rui, Maier Julia, Gorki Anna-Dorothea, Huber Kilian V M, Sharif Omar, Starkl Philipp, Saluzzo Simona, Quattrone Federica, Gawish Riem, Lakovits Karin, Aichinger Michael C, Radic-Sarikas Branka, Lardeau Charles-Hugues, Hladik Anastasiya, Korosec Ana, Brown Markus, Vaahtomeri Kari, Duggan Michelle, Kerjaschki Dontscho, Esterbauer Harald, Colinge Jacques, Eisenbarth Stephanie C, Decker Thomas, Bennett Keiryn L, Kubicek Stefan, Sixt Michael, Superti-Furga Giulio, Knapp Sylvia
Fast volumetric calcium imaging across multiple cortical layers using sculpted light.
Prevedel Robert, Verhoef Aart J, Pernía-Andrade Alejandro J, Weisenburger Siegfried, Huang Ben S, Nöbauer Tobias, Fernández Alma, Delcour Jeroen E, Golshani Peyman, Baltuska Andrius, Vaziri Alipasha
Two Independent Pathways within Selective Autophagy Converge to Activate Atg1 Kinase at the Vacuole.
Torggler Raffaela, Papinski Daniel, Brach Thorsten, Bas Levent, Schuschnig Martina, Pfaffenwimmer Thaddäus, Rohringer Sabrina, Matzhold Tamara, Schweida David, Brezovich Andrea, Kraft Claudine
Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity.
Putz Eva Maria, Majoros Andrea, Gotthardt Dagmar, Prchal-Murphy Michaela, Zebedin-Brandl Eva Maria, Fux Daniela Alexandra, Schlattl Andreas, Schreiber Robert D, Carotta Sebastian, Müller Mathias, Gerner Christopher, Decker Thomas, Sexl Veronika
MEK1 is required for the development of NRAS-driven leukemia.
Nowacka Joanna D, Baumgartner Christian, Pelorosso Cristiana, Roth Mareike, Zuber Johannes, Baccarini Manuela
Scarless Gene Tagging with One-Step Transformation and Two-Step Selection in Saccharomyces cerevisiae and Schizosaccharomyces pombe.
Landgraf Dirk, Huh Dann, Hallacli Erinc, Lindquist Susan
Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.
Reimão-Pinto Madalena M, Manzenreither Raphael A, Burkard Thomas R, Sledz Pawel, Jinek Martin, Mechtler Karl, Ameres Stefan L
A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation.
Molodtsov Maxim I, Mieck Christine, Dobbelaere Jeroen, Dammermann Alexander, Westermann Stefan, Vaziri Alipasha
Levels of the soluble LDL receptor-relative LR11 decrease in overweight individuals with type 2 diabetes upon diet-induced weight loss.
Berk Kirsten A, Vongpromek Ranitha, Jiang Meizi, Schneider Wolfgang J, Timman Reinier, Verhoeven Adrie J M, Bujo Hideaki, Sijbrands Eric J G, Mulder Monique T
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
Wrasidlo Wolfgang, Tsigelny Igor F, Price Diana L, Dutta Garima, Rockenstein Edward, Schwarz Thomas C, Ledolter Karin, Bonhaus Douglas, Paulino Amy, Eleuteri Simona, Skjevik Åge A, Kouznetsova Valentina L, Spencer Brian, Desplats Paula, Gonzalez-Ruelas Tania, Trejo-Morales Margarita, Overk Cassia R, Winter Stefan, Zhu Chunni, Chesselet Marie-Francoise, Meier Dieter, Moessler Herbert, Konrat Robert, Masliah Eliezer
Multi-pass microscopy.
Juffmann Thomas, Klopfer Brannon B, Frankort Timmo L I, Haslinger Philipp, Kasevich Mark A