Targeted decay of a regulatory small RNA by an adaptor protein for RNase E and counteraction by an anti-adaptor RNA.
Göpel Yvonne, Papenfort Kai, Reichenbach Birte, Vogel Jörg, Görke Boris
CLP1 links tRNA metabolism to progressive motor-neuron loss.
Hanada Toshikatsu, Weitzer Stefan, Mair Barbara, Bernreuther Christian, Wainger Brian J, Ichida Justin, Hanada Reiko, Orthofer Michael, Cronin Shane J, Komnenovic Vukoslav, Minis Adi, Sato Fuminori, Mimata Hiromitsu, Yoshimura Akihiko, Tamir Ido, Rainer Johannes, Kofler Reinhard, Yaron Avraham, Eggan Kevin C, Woolf Clifford J, Glatzel Markus, Herbst Ruth, Martinez Javier, Penninger Josef M
MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral tolerance.
Zmajkovicova Katarina, Jesenberger Veronika, Catalanotti Federica, Baumgartner Christian, Reyes Gloria, Baccarini Manuela
The muscle dystrophy-causing ΔK32 lamin A/C mutant does not impair the functions of the nucleoplasmic lamin-A/C-LAP2α complex in mice.
Pilat Ursula, Dechat Thomas, Bertrand Anne T, Woisetschläger Nikola, Gotic Ivana, Spilka Rita, Biadasiewicz Katarzyna, Bonne Gisèle, Foisner Roland
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.
Versteeg Gijs A, Rajsbaum Ricardo, Sánchez-Aparicio Maria Teresa, Maestre Ana M, Valdiviezo Julio, Shi Mude, Inn Kyung-Soo, Fernandez-Sesma Ana, Jung Jae, García-Sastre Adolfo
Ribosome heterogeneity: another level of complexity in bacterial translation regulation.
Byrgazov Konstantin, Vesper Oliver, Moll Isabella
CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.
Bancerek Joanna, Poss Zachary C, Steinparzer Iris, Sedlyarov Vitaly, Pfaffenwimmer Thaddäus, Mikulic Ivana, Dölken Lars, Strobl Birgit, Müller Mathias, Taatjes Dylan J, Kovarik Pavel
Embryonic stem cells facilitate the isolation of persistent clonal cardiovascular progenitor cell lines and leukemia inhibitor factor maintains their self-renewal and myocardial differentiation potential in vitro.
Hoebaus Julia, Heher Philipp, Gottschamel Teresa, Scheinast Matthias, Auner Harmen, Walder Diana, Wiedner Marc, Taubenschmid Jasmin, Miksch Maximilian, Sauer Thomas, Schultheis Martina, Kuzmenkin Alexey, Seiser Christian, Hescheler Juergen, Weitzer Georg
Dissecting the role of the Atg12-Atg5-Atg16 complex during autophagosome formation.
Walczak Marta, Martens Sascha
Stable transgenesis in the marine annelid Platynereis dumerilii sheds new light on photoreceptor evolution.
Backfisch Benjamin, Veedin Rajan Vinoth Babu, Fischer Ruth M, Lohs Claudia, Arboleda Enrique, Tessmar-Raible Kristin, Raible Florian
Novel bilobe components in Trypanosoma brucei identified using proximity-dependent biotinylation.
Morriswood Brooke, Havlicek Katharina, Demmel Lars, Yavuz Sevil, Sealey-Cardona Marco, Vidilaseris Keni, Anrather Dorothea, Kostan Julius, Djinovic-Carugo Kristina, Roux Kyle J, Warren Graham
Small ubiquitin-like modifier conjugating enzyme with active site mutation acts as dominant negative inhibitor of SUMO conjugation in arabidopsis(F).
Tomanov Konstantin, Hardtke Christian, Budhiraja Ruchika, Hermkes Rebecca, Coupland George, Bachmair Andreas
¹H, ¹³C, and ¹⁵N backbone and side chain resonance assignments of the C-terminal DNA binding and dimerization domain of v-Myc.
Kızılsavaş Gönül, Saxena Saurabh, Żerko Szymon, Koźmiński Wiktor, Bister Klaus, Konrat Robert
¹H, ¹³C and ¹⁵N resonance assignments of human BASP1.
Geist Leonhard, Zawadzka-Kazimierczuk Anna, Saxena Saurabh, Żerko Szymon, Koźmiński Wiktor, Konrat Robert
Essential, non-redundant roles of B-Raf and Raf-1 in Ras-driven skin tumorigenesis.
Kern F, Doma E, Rupp C, Niault T, Baccarini M
On the Contribution of Linear Correlations to Quasi-harmonic Conformational Entropy in Proteins.
Polyansky Anton A, Kuzmanic Antonija, Hlevnjak Mario, Zagrovic Bojan
Protein Electrostatic Properties Predefining the Level of Surface Hydrophobicity Change upon Phosphorylation.
Polyansky Anton A, Zagrovic Bojan
Msl1-mediated dimerization of the dosage compensation complex is essential for male X-chromosome regulation in Drosophila.
Hallacli Erinc, Lipp Michael, Georgiev Plamen, Spielman Clare, Cusack Stephen, Akhtar Asifa, Kadlec Jan
Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation.
Romanov Julia, Walczak Marta, Ibiricu Iosune, Schüchner Stefan, Ogris Egon, Kraft Claudine, Martens Sascha
SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism in C. elegans centriole assembly.
Qiao Renping, Cabral Gabriela, Lettman Molly M, Dammermann Alexander, Dong Gang