A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.
Catalanotti Federica, Reyes Gloria, Jesenberger Veronika, Galabova-Kovacs Gergana, de Matos Simoes Ricardo, Carugo Oliviero, Baccarini Manuela
B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis.
Sobczak I, Galabova-Kovacs G, Sadzak I, Kren A, Christofori G, Baccarini M
Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development.
Galabova-Kovacs Gergana, Catalanotti Federica, Matzen Dana, Reyes Gloria X, Zezula Jürgen, Herbst Ruth, Silva Alcino, Walter Ingrid, Baccarini Manuela
ERK and beyond: insights from B-Raf and Raf-1 conditional knockouts.
Galabova-Kovacs Gergana, Kolbus Andrea, Matzen Dana, Meissl Katrin, Piazzolla Daniela, Rubiolo Cristina, Steinitz Katharina, Baccarini Manuela
Essential role of B-Raf in ERK activation during extraembryonic development.
Galabova-Kovacs Gergana, Matzen Dana, Piazzolla Daniela, Meissl Katrin, Plyushch Tatiana, Chen Adele P, Silva Alcino, Baccarini Manuela
Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling.
Piazzolla Daniela, Meissl Katrin, Kucerova Lucia, Rubiolo Cristina, Baccarini Manuela
Second nature: biological functions of the Raf-1 "kinase".
Baccarini Manuela
Raf-1 regulates Rho signaling and cell migration.
Ehrenreiter Karin, Piazzolla Daniela, Velamoor Vanishree, Sobczak Izabela, Small J Victor, Takeda Junji, Leung Thomas, Baccarini Manuela