Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.
Sunshine Sara, Puschnik Andreas S, Replogle Joseph M, Laurie Matthew T, Liu Jamin, Zha Beth Shoshana, Nuñez James K, Byrum Janie R, McMorrow Aidan H, Frieman Matthew B, Winkler Juliane, Qiu Xiaojie, Rosenberg Oren S, Leonetti Manuel D, Ye Chun Jimmie, Weissman Jonathan S, DeRisi Joseph L, Hein Marco Y
piRNA processing by a trimeric Schlafen-domain nuclease.
Podvalnaya Nadezda, Bronkhorst Alfred W, Lichtenberger Raffael, Hellmann Svenja, Nischwitz Emily, Falk Torben, Karaulanov Emil, Butter Falk, Falk Sebastian, Ketting René F
Simulating structurally variable nuclear pore complexes for microscopy.
Theiss Maria, Hériché Jean-Karim, Russell Craig, Helekal David, Soppitt Alisdair, Ries Jonas, Ellenberg Jan, Brazma Alvis, Uhlmann Virginie
Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II.
Flores-Solis David, Lushpinskaia Irina P, Polyansky Anton A, Changiarath Arya, Boehning Marc, Mirkovic Milana, Walshe James, Pietrek Lisa M, Cramer Patrick, Stelzl Lukas S, Zagrovic Bojan, Zweckstetter Markus
Characterisation of TbSmee1 suggests endocytosis allows surface-bound cargo to enter the trypanosome flagellar pocket.
Schichler Daja, Konle Antonia, Spath Eva-Maria, Riegler Sina, Klein Alexandra, Seleznev Anna, Jung Sisco, Wuppermann Timothy, Wetterich Noah, Borges Alyssa, Meyer-Natus Elisabeth, Havlicek Katharina, Pérez Cabrera Sonia, Niedermüller Korbinian, Sajko Sara, Dohn Maximilian, Malzer Xenia, Riemer Emily, Tumurbaatar Tuguldur, Djinovic-Carugo Kristina, Dong Gang, Janzen Christian J, Morriswood Brooke
Chemical Acetylation of Ligands and Two-Step Digestion Protocol for Reducing Codigestion in Affinity Purification-Mass Spectrometry.
Hollenstein David M, Maurer-Granofszky Margarita, Reiter Wolfgang, Anrather Dorothea, Gossenreiter Thomas, Babic Riccardo, Hartl Natascha, Kraft Claudine, Hartl Markus
Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling.
Harding Olivia, Holzer Elisabeth, Riley Julia F, Martens Sascha, Holzbaur Erika L F
Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model.
Horánszky Alex, Shashikadze Bachuki, Elkhateib Radwa, Lombardo Salvo Danilo, Lamberto Federica, Zana Melinda, Menche Jörg, Fröhlich Thomas, Dinnyés András
AutoCore: A network-based definition of the core module of human autoimmunity and autoinflammation.
Guthrie Julia, Köstel Bal Sevgi, Lombardo Salvo Danilo, Müller Felix, Sin Celine, Hütter Christiane V R, Menche Jörg, Boztug Kaan
Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex.
Jaksch Dhaarsini, Irnstorfer Johanna, Kalman Petra-Franziska, Martinez Javier
Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Rasool Reyaz Ur, O'Connor Caitlin M, Das Chandan Kanta, Alhusayan Mohammed, Verma Brijesh Kumar, Islam Sehbanul, Frohner Ingrid E, Deng Qu, Mitchell-Velasquez Erick, Sangodkar Jaya, Ahmed Aqila, Linauer Sarah, Mudrak Ingrid, Rainey Jessica, Zawacki Kaitlin P, Suhan Tahra K, Callahan Catherine G, Rebernick Ryan, Natesan Ramakrishnan, Siddiqui Javed, Sauter Guido, Thomas Dafydd, Wang Shaomeng, Taylor Derek J, Simon Ronald, Cieslik Marcin, Chinnaiyan Arul M, Busino Luca, Ogris Egon, Narla Goutham, Asangani Irfan A
Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet.
Meyenberg Mathilde, Hakobyan Anna, Papac-Milicevic Nikolina, Göderle Laura, Langner Franziska L, Markovic Mateo, Lee Ji-Hyun, Koo Bon-Kyoung, Busslinger Georg A, da Silva Israel Tojal, Binder Christoph J, Menche Jörg, Loizou Joanna I
Studies of proline conformational dynamics in IDPs by C-detected cross-correlated NMR relaxation.
Schiavina Marco, Konrat Ruth, Ceccolini Irene, Mateos Borja, Konrat Robert, Felli Isabella C, Pierattelli Roberta
SPOP targets the immune transcription factor IRF1 for proteasomal degradation.
Schwartz Irene, Vunjak Milica, Budroni Valentina, Cantoran García Adriana, Mastrovito Marialaura, Soderholm Adrian, Hinterndorfer Matthias, de Almeida Melanie, Hacker Kathrin, Wang Jingkui, Froussios Kimon, Jude Julian, Decker Thomas, Zuber Johannes, Versteeg Gijs A
p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons.
Trapannone Riccardo, Romanov Julia, Martens Sascha
Pathogen-induced m6A dynamics affect plant immunity.
Prall Wil, Sheikh Arsheed H, Bazin Jeremie, Bigeard Jean, Almeida-Trapp Marilia, Crespi Martin, Hirt Heribert, Gregory Brian D
ModelRevelator: Fast phylogenetic model estimation via deep learning.
Burgstaller-Muehlbacher Sebastian, Crotty Stephen M, Schmidt Heiko A, Reden Franziska, Drucks Tamara, von Haeseler Arndt
Lipid saturation controls nuclear envelope function.
Romanauska Anete, Köhler Alwin
Structural evidence for elastic tethers connecting separating chromosomes in crane-fly spermatocytes.
Forer Arthur, Otsuka Shotaro
Particle fusion of super-resolution data reveals the unit structure of Nup96 in Nuclear Pore Complex.
Wang Wenxiu, Jakobi Arjen, Wu Yu-Le, Ries Jonas, Stallinga Sjoerd, Rieger Bernd