During the development of gametes, such as egg and sperm cells in humans, chromosomes are broken and rearranged at many positions. Using state of the art technology, the research group of Franz Klein, professor for genetics at the Max F. Perutz Laboratories of the University of Vienna, has analyzed this process at high resolution. The surprising observations regarding the mechanism of meiosis are now published in the scientific top-journal Cell.
Without meiosis there would be no sexual reproduction, as germ cells have to be generated in this specialized cell division. Meiosis results in daughter cells containing a single, complete set of chromosomes, while body cells contain two sets. During fertilization, when sperm and egg fuse, their sets of chromosomes are combined to form a diploid embryo to close the cycle.
There are 46 chromosomes in every human cell, 23 maternal and 23 paternal ones. When germ cells are produced, one aspect of the reduction in chromosome numbers comes from merging maternal and paternal chromosomes to form a single daughter chromosome – a mechanisms called recombination. “The more we learn about meiosis, the more mysterious it becomes.”, says Franz Klein from the Department for chromosome biology of the University of Vienna. “It is surprising that maternal and paternal chromosomes find each other at all. Because at the time of interaction all chromosomes have generated a sister and are tightly connected with her like a Siamese twin. Normally, in non-meiotic cells, chromosomes only interact and exchange with the sister chromosome. However, during the development of germ cells, only the exchange between parental chromosomes can guarantee the production of daughter cells with the right number of chromosomes.” explains Klein.
Franz Klein and his research team have analyzed components of the protein machinery, which initiates recombination by DNA-breakage. They created a high resolution map of the chromosomes and marked the interaction sites with those proteins. “Thanks to DNA microarray-technology, we get a resolution in the nanometer range, with insights unimaginable before.” says Klein. The researchers were surprised to find the DNA-breaking machine tightly associated with chromosomal axis regions, instead of being soluble - an observation with far reaching consequences.
One of the many riddles in meiosis was how breaks on chromosomes impede the occurrence of other breaks in their vicinity. Earlier research had shown that each individual DNA-breakage complex only works a single time. “As we now know that these machines are anchored, we understand why there is preferentially a single break per region. The locally bound machine has fired and other machines can’t get there as they are anchored to other chromosomal regions”, explains Klein.
Healthy chromosomes can form DNA loops, which are, in meiosis, connected by a protein axis. Defective genes can cause chromosomes to lose this shape. “No one could understand why the shape of chromosomes influences the function of the DNA-break machines. Now we know that these machines have to anchor between loops on the chromosome axis. If their loop-environment changes they anchor in different regions or lose functionality altogether”, says Klein.
Sister chromosomes are connected like Siamese twins along the chromosome axis, where the DNA-break machines are anchored. It was very mysterious, how the sister chromosome is prevented to take part in the repair of DNA breaks during meiosis, despite being so close to the damage. A special feature of meiosis is the formation of a zone along the chromosome axis that inhibits recombination. “We think that the DNA-break machines are anchored at the axis to position the breaks right within the recombination inhibiting zone. This may attract the sister chromosome loop, which remains trapped in the recombination inhibiting zone by one of the two ends flanking the break, while the second end docks off to form a search tentacle for finding the paternal chromosome.”
“We have evidence for many details of this scenario – but most importantly, the inhibition of the involvement of the sister breaks down, if the anchoring of the DNA-break machines is defective. This indicates that anchoring may be indeed a key mechanism to control the sister. The result of a sister, hyperactive for DNA-break repair in meiosis is the death or severe impairment of the developing embryo.
Funding
The published work was conducted within the framework of the Special Research Program F34-“Chromosome Dynamics” of the Austrian Science Fund FWF. Seven research groups of the MFPL and the Institute of Molecular Pathology (IMP) collaborate in this research program to unravel questions of chromosome biology. Coordination: Franz Klein and Jan Michael Peters, this year’s Wittgenstein awardee.
Original publication in Cell:
Silvia Panizza, Marco A. Mendoza, Marc Berlinger, Lingzhi Huang, Alain Nicolas, Katsuhiko Shirahige, Franz Klein (2011) Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination.
Structure and Dynamics of the envelope glycoprotein of HIV-1 during Fusion
15:00
Lecture Hall B, VBC5 & Zoom
Thomas Juffmann
Sergi Padilla-ParraDate: 2025-01-09, Time: 15:00:00, Speaker: Sergi Padilla-Parra, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: King's College London, Host: Thomas Juffmann
Cancer aneuploidy: From selection pressures to cellular vulnerabilities
11:00 IMBA/GMI Lecture Hall Anna Obenauf Uri Ben-DavidDate: 2025-01-09, Time: 11:00:00, Speaker: Uri Ben-David, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Tel Aviv University, Host: Anna Obenauf
Monday Seminar (Internal)
12:30 IMP Lecture Hall KRASNOVID Filipp (Mari-Ordonez), ROTHE Patricia (Plaschka), KROGULL Daniel (Burga)Date: 2025-01-13, Time: 12:30:00, Speaker: KRASNOVID Filipp (Mari-Ordonez)ROTHE Patricia (Plaschka)KROGULL Daniel (Burga), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
The hidden gems of antiviral immune systems in bacteria
11:00 IMBA/GMI Lecture Hall Irma Querques Stan BrounsDate: 2025-01-16, Time: 11:00:00, Speaker: Stan Brouns, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Delft University of Technology, Host: Irma Querques
Monday Seminar (Internal)
12:30 IMP Lecture Hall VICIC Ziga (Jachowicz), GRÜNEWALD Jakob (Obenauf), MANOLOVA Toni (Falk)Date: 2025-01-20, Time: 12:30:00, Speaker: VICIC Ziga (Jachowicz)GRÜNEWALD Jakob (Obenauf)MANOLOVA Toni (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Deriving a genetic regulatory network from an optimization principle
14:00 Lecture Hall B, VBC5 & Zoom Bojan Zagrovic Gasper TkacikDate: 2025-01-23, Time: 14:00:00, Speaker: Gasper Tkacik, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: ISTA, Host: Bojan Zagrovic
Title to be announced
11:00 UBB - Lecture Hall 2 & Zoom Hayk Palabikyan Anais CarioDate: 2025-01-23, Time: 11:00:00, Speaker: Anais Cario, Location: UBB - Lecture Hall 2 & Zoom, Type: DOME Lecture Series, Institute: French National Centre for Scientific Research, Host: Hayk Palabikyan
Title to be announced
11:00 IMBA/GMI Lecture Hall Egon Ogris Anne BertolottiDate: 2025-01-23, Time: 11:00:00, Speaker: Anne Bertolotti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MCR Laboratory of Molecular Biology, Host: Egon Ogris
Size Matters: The unique exocytosis mechanism of large secretory vesicles
10:00 IMBA/GMI Lecture Hall Andi Pauli Ori AvinoamDate: 2025-01-27, Time: 10:00:00, Speaker: Ori Avinoam, Location: IMBA/GMI Lecture Hall, Type: IMP Impromptu Seminar, Institute: Weizmann Institute, Host: Andi Pauli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WILLIAMS Thomas (Clausen), SCARAMUZZA Federico (Tessmar), WALTER Mateusz (Querques)Date: 2025-01-27, Time: 12:30:00, Speaker: WILLIAMS Thomas (Clausen)SCARAMUZZA Federico (Tessmar)WALTER Mateusz (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Decidualisation of human endometrium: from evolutionary insights to novel mechanisms of disease
13:15 UBB - Lecture Hall 1 Mihaela Pavlicev Jan BrosensDate: 2025-01-28, Time: 13:15:00, Speaker: Jan Brosens, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: University of Warwick, Host: Mihaela Pavlicev
Design of New Protein Functions Using Deep Learning
18:00 Zoom Alwin Köhler David BakerDate: 2025-01-29, Time: 18:00:00, Speaker: David Baker, Location: Zoom, Type: VBC Regular Seminar, Institute: University of Washington School, Host: Alwin Köhler
Title to be announced
14:00 Lecture Hall B, VBC5 & Zoom Ivan Yudushkin Marcus TaylorDate: 2025-01-30, Time: 14:00:00, Speaker: Marcus Taylor, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Max Planck Institute for Infection Biology, Berlin, Host: Ivan Yudushkin
Reactive Tracers in Chemical Substances: Compound-specific Isotope Analysis to Characterize Transformation of Organic Compounds
12:00 Zoom Thilo Hofmann Martin ElsnerDate: 2025-01-30, Time: 12:00:00, Speaker: Martin Elsner, Location: Zoom, Type: CeMESS Lecture Series, Institute: Technical University of Munich, Host: Thilo Hofmann
Transposable elements in development and reprogramming
11:00 IMBA/GMI Lecture Hall Julius Brennecke Maria-Elena Torres-PadillaDate: 2025-01-30, Time: 11:00:00, Speaker: Maria-Elena Torres-Padilla, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Ludwig-Maximilians-University Munich, Host: Julius Brennecke
Monday Seminar (Internal)
12:30 IMP Lecture Hall CRUZ Joseph (Gerlich), GHEORGHITA Andreea (Clausen), GALUSKA Philipp (Djinovic)Date: 2025-02-03, Time: 12:30:00, Speaker: CRUZ Joseph (Gerlich)GHEORGHITA Andreea (Clausen)GALUSKA Philipp (Djinovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Deciphering driving forces of cell fate decision at single-cell resolution in time and space
11:00 GMI Orange Seminar Room Alex Stark Dominic GruenDate: 2025-02-04, Time: 11:00:00, Speaker: Dominic Gruen, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: University of Würzburg, Host: Alex Stark
Exploring dynamic regulation and function of the nuclear lamina
10:30 IMP Lecture Hall David Haselbach Abigail BuchwalterDate: 2025-02-05, Time: 10:30:00, Speaker: Abigail Buchwalter, Location: IMP Lecture Hall, Type: Impromptu Seminar, Institute: UCSF, Host: David Haselbach
Ectomycorrhizal fungi as drivers of forest ecosystem processes
12:00 UBB - Lecture Hall 2 & Zoom Mark Anthony Filipa CoxxDate: 2025-02-06, Time: 12:00:00, Speaker: Filipa Coxx, Location: UBB - Lecture Hall 2 & Zoom, Type: CeMESS Lecture Series, Institute: University of Manchester, Host: Mark Anthony
Title to be announced
11:00 IMBA/GMI Lecture Hall Fred Berger Thibaut BrunetDate: 2025-02-06, Time: 11:00:00, Speaker: Thibaut Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institut Pasteur, University Paris-Cite, Host: Fred Berger
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GRIGOREVA Elizaveta (Nordborg), KOHOUTKOVA Eliska (Clausen), STEINACKER Thomas (Gerlich)Date: 2025-02-10, Time: 12:30:00, Speaker: GRIGOREVA Elizaveta (Nordborg)KOHOUTKOVA Eliska (Clausen)STEINACKER Thomas (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Fred Berger Jeff BoekeDate: 2025-02-13, Time: 11:00:00, Speaker: Jeff Boeke, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: NYU Langdone Health, Host: Fred Berger
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RAFFL Gerald (Ameres), VULIN Milica (Obenauf), FISCHER Andre (Tanaka)Date: 2025-02-17, Time: 12:30:00, Speaker: RAFFL Gerald (Ameres)VULIN Milica (Obenauf)FISCHER Andre (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Defining the autism cell phenotypic landscape
11:00 IMBA/GMI Lecture Hall Dea Slade Gaia NovarinoDate: 2025-02-20, Time: 11:00:00, Speaker: Gaia Novarino, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: ISTA, Host: Dea Slade
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BAYERL Jonas (Zuber), ZABOLOCKI Michael (Knoblich), EDER Stephanie (Zimmer)Date: 2025-02-24, Time: 12:30:00, Speaker: BAYERL Jonas (Zuber)ZABOLOCKI Michael (Knoblich)EDER Stephanie (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz Cedric FeschotteDate: 2025-02-27, Time: 11:00:00, Speaker: Cedric Feschotte, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Cornell University, Host: Joanna Jachowicz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KROETENHEERDT Eva (Leonard), RÖHSNER Josef (Pauli), RIABOV Daria (Plaschka)Date: 2025-03-03, Time: 12:30:00, Speaker: KROETENHEERDT Eva (Leonard)RÖHSNER Josef (Pauli)RIABOV Daria (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz Zach SmithDate: 2025-03-06, Time: 11:00:00, Speaker: Zach Smith, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: MIT, Host: Joanna Jachowicz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None CHO Chung Hyun (Berger), SEIDL Carina (Tanaka), MIGOTTI Mario (Konrat)Date: 2025-03-10, Time: 12:30:00, Speaker: CHO Chung Hyun (Berger)SEIDL Carina (Tanaka)MIGOTTI Mario (Konrat), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Diana Pinheiro, Alex Stark Joaquina DelasDate: 2025-03-11, Time: 11:00:00, Speaker: Joaquina Delas, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: University College London, Host: Diana Pinheiro, Alex Stark
SY-Stem
Mar 12 - Mar 14 IMP Lecture Hall NoneDate: 2025-03-12, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None CHEN Shenzhi (Stark), BINDL Michael (Leeb), JÄGER Martin (Obenauf)Date: 2025-03-17, Time: 12:30:00, Speaker: CHEN Shenzhi (Stark)BINDL Michael (Leeb)JÄGER Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Unravelling the inner secrets of cells with live-cell super-resolution microscopy
10:00 Lecture Hall A, VBC 5 Jonas Ries Francesca BottanelliDate: 2025-03-19, Time: 10:00:00, Speaker: Francesca Bottanelli, Location: Lecture Hall A, VBC 5, Type: Impromptu Seminar, Institute: Freie Universität Berlin, Host: Jonas Ries
Title to be announced
11:00 IMBA/GMI Lecture Hall Joao Matos Geert KopsDate: 2025-03-20, Time: 11:00:00, Speaker: Geert Kops, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Joao Matos
Monday Seminar (Internal)
12:30 IMP Lecture Hall None MAYA Juan (Balzarotti), DOSA Anna (Clausen), KOBER Julia (Ramundo)Date: 2025-03-24, Time: 12:30:00, Speaker: MAYA Juan (Balzarotti)DOSA Anna (Clausen)KOBER Julia (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alwin Köhler Martin BeckDate: 2025-03-27, Time: 11:00:00, Speaker: Martin Beck, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Biophysics, Host: Alwin Köhler
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HOLZER Elisabeth (Martens), THEMANN Jan (Knoblich), GROSS Angelina (Dagdas)Date: 2025-03-31, Time: 12:30:00, Speaker: HOLZER Elisabeth (Martens)THEMANN Jan (Knoblich)GROSS Angelina (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Sebastian Falk Rotem SorekDate: 2025-04-03, Time: 11:00:00, Speaker: Rotem Sorek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute, Host: Sebastian Falk
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GROH Roan (Dagdas), CHAO Victor (Huis), KHANDEKAR Ameya (Ellis)Date: 2025-04-07, Time: 12:30:00, Speaker: GROH Roan (Dagdas)CHAO Victor (Huis)KHANDEKAR Ameya (Ellis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
"Tiles of Life" Symposium
Apr 10 - Apr 11 IMP Lecture Hall SMICH communityDate: 2025-04-10, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall , Type: Symposium, Institute: None, Host: SMICH community
Tiles of Life - Student Symposium
Apr 10 - Apr 11 IMP lecture hall, Vienna BioCenterThe symposium will explore the intricate "tiles" that form the vast and diverse fields of molecular biology and aims to foster discussions and inspire collaborations by bringing the “tiles of life” together. The program includes several talks by esteemed and international speakers sharing their latest findings to link the molecular mosaic of the cell - from structures to organisms. Additionally, we will highlight the research of the SMICH community on campus by complementing the program with student talks.
Monday Seminar (Internal)
12:30 IMP Lecture Hall None OKUN Anastasia (Karagöz), COLLISON Robert (Ramundo), WELZL Paul (Balzarotti/Plaschka)Date: 2025-04-14, Time: 12:30:00, Speaker: OKUN Anastasia (Karagöz)COLLISON Robert (Ramundo)WELZL Paul (Balzarotti/Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Anton Goloborodko Maria Cristina GambettaDate: 2025-04-24, Time: 11:00:00, Speaker: Maria Cristina Gambetta, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lausanne, Host: Anton Goloborodko
Title to be announced
10:30 IMP Seminar Room 1.014/16 Diana Pinheiro Takshi HiragiDate: 2025-04-25, Time: 10:30:00, Speaker: Takshi Hiragi, Location: IMP Seminar Room 1.014/16, Type: IMP Impromptu Seminar, Institute: Hubrecht Institute, Host: Diana Pinheiro
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SUWITA Johannes (Pauli), GRABARCZYK Daniel (Clausen), PANDA Aswini (Falk)Date: 2025-04-28, Time: 12:30:00, Speaker: SUWITA Johannes (Pauli)GRABARCZYK Daniel (Clausen)PANDA Aswini (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KIM Olena (Knoblich), JOB Nikhil (Dolan), ADELMANN Leonie (Raible)Date: 2025-05-05, Time: 12:30:00, Speaker: KIM Olena (Knoblich)JOB Nikhil (Dolan)ADELMANN Leonie (Raible), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Microsymposium on RNA Biology'
May 07 - May 09 IMP Lecture Hall NoneDate: 2025-05-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
EMBO meeting on RNA meets Protein decay
May 11 - May 14 IMP Lecture Hall NoneDate: 2025-05-11, Time: 14:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SCIBISZ Grzegorz (Karagöz), VAN GENDEREN Emiel (Rivron), BOZKURT Miray (Tanaka)Date: 2025-05-12, Time: 12:30:00, Speaker: SCIBISZ Grzegorz (Karagöz)VAN GENDEREN Emiel (Rivron)BOZKURT Miray (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alex Stark Chuna Ram ChoudharyDate: 2025-05-15, Time: 11:00:00, Speaker: Chuna Ram Choudhary, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Alex Stark
Monday Seminar (Internal)
12:30 IMP Lecture Hall None POTTENDORFER Elisabeth (Obenauf), WALLNER Eva-Sophie (Dolan), BECKER Moritz (Leeb)Date: 2025-05-19, Time: 12:30:00, Speaker: POTTENDORFER Elisabeth (Obenauf)WALLNER Eva-Sophie (Dolan)BECKER Moritz (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Elif Karagöz Manuel LeonettiDate: 2025-05-22, Time: 11:00:00, Speaker: Manuel Leonetti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: CZ Biohub San Francisco, Host: Elif Karagöz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIMITROVA Polina (Van der Veeken), STRAVS Ana (Knoblich), SCHÖNLEIN Martin (Obenauf)Date: 2025-05-26, Time: 12:30:00, Speaker: DIMITROVA Polina (Van der Veeken)STRAVS Ana (Knoblich)SCHÖNLEIN Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SABATH Kevin (Plaschka/Stark), MANCHENO JUNCOSA Estela (Mendjan), HORENKAMP Simone (Tanaka)Date: 2025-06-02, Time: 12:30:00, Speaker: SABATH Kevin (Plaschka/Stark)MANCHENO JUNCOSA Estela (Mendjan)HORENKAMP Simone (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Julius Brennecke Stefan MundlosDate: 2025-06-12, Time: 11:00:00, Speaker: Stefan Mundlos, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Molecular Genetics, Host: Julius Brennecke
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BERGER Sonja (Goloborodko), KOWALD Saskia (Gaidt), KAPRAL Thomas (Zagrovic)Date: 2025-06-16, Time: 12:30:00, Speaker: BERGER Sonja (Goloborodko)KOWALD Saskia (Gaidt)KAPRAL Thomas (Zagrovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joris Van der Veeken Nikhil JoshiDate: 2025-06-18, Time: 11:00:00, Speaker: Nikhil Joshi, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Yale University, Host: Joris Van der Veeken
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BUCHERON Chloe (Menche), KRUMWIEDE Luisa (Gaidt), PACHANO Tomas (Stark)Date: 2025-06-23, Time: 12:30:00, Speaker: BUCHERON Chloe (Menche)KRUMWIEDE Luisa (Gaidt)PACHANO Tomas (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SCHINDLER Lukas (Schlögelhofer), MANDLBURGER Nikolaus (Stark), OTTO Magdalena (Leonard)Date: 2025-06-30, Time: 12:30:00, Speaker: SCHINDLER Lukas (Schlögelhofer)MANDLBURGER Nikolaus (Stark)OTTO Magdalena (Leonard), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Marco Hein Matthias MannDate: 2025-07-03, Time: 11:00:00, Speaker: Matthias Mann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max-Planck Institute of Biochemistry, Host: Marco Hein
Monday Seminar (Internal)
12:30 IMP Lecture Hall None TRUS Palina (Peters), KOBAKHIDZE George (Dong), KONGSTED Thea (Dolan)Date: 2025-07-07, Time: 12:30:00, Speaker: TRUS Palina (Peters)KOBAKHIDZE George (Dong)KONGSTED Thea (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Erinc Hallacli Simon AlbertiDate: 2025-07-10, Time: 11:00:00, Speaker: Simon Alberti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: TU Dresden, Host: Erinc Hallacli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RUSCH Emma (Golobordko), VELIKOV Daniel (Matos), VOGEL Alexander (Clausen/Yudushkin)Date: 2025-07-14, Time: 12:30:00, Speaker: RUSCH Emma (Golobordko)VELIKOV Daniel (Matos)VOGEL Alexander (Clausen/Yudushkin), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None ANGELOPOULOU Eleni (Ellis), SCHAFFER Petra (Grade), RAMIREZ America (Köhler)Date: 2025-07-21, Time: 12:30:00, Speaker: ANGELOPOULOU Eleni (Ellis)SCHAFFER Petra (Grade)RAMIREZ America (Köhler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIMITRIADI Anna (Mendjan), LEITNER Moritz (Martinez), BRADAMANTE Gabriele (Biooptics)Date: 2025-07-28, Time: 12:30:00, Speaker: DIMITRIADI Anna (Mendjan)LEITNER Moritz (Martinez)BRADAMANTE Gabriele (Biooptics), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None LI Wenxin (Zimmer), FISCHER Felix (Zagrovic), ABESAMIS Kim Ivan (Dong)Date: 2025-08-04, Time: 12:30:00, Speaker: LI Wenxin (Zimmer)FISCHER Felix (Zagrovic)ABESAMIS Kim Ivan (Dong), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KLEIFELD Justus (Urban), MCATEER Tara (Pinheiro), BHATTACHARYA Mrinnanda (Zimmer)Date: 2025-08-11, Time: 12:30:00, Speaker: KLEIFELD Justus (Urban)MCATEER Tara (Pinheiro)BHATTACHARYA Mrinnanda (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BELL Lillie (Clausen), MIHAILOVIC Milica (Karagöz), GUYNES Keroshini (Jachowicz)Date: 2025-08-18, Time: 12:30:00, Speaker: BELL Lillie (Clausen)MIHAILOVIC Milica (Karagöz)GUYNES Keroshini (Jachowicz), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BOHL VIALLEFONT Gregoire (Nordborg), MARCHIORI Elisa (Van der Veeken), JAHNEL Stefan (Mendjan)Date: 2025-08-25, Time: 12:30:00, Speaker: BOHL VIALLEFONT Gregoire (Nordborg)MARCHIORI Elisa (Van der Veeken)JAHNEL Stefan (Mendjan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KIRCHGATTERER Paul (Gaidt), ACHLEITNER Sonja (Martens), KAYA Oguzhan (Knoblich)Date: 2025-09-01, Time: 12:30:00, Speaker: KIRCHGATTERER Paul (Gaidt)ACHLEITNER Sonja (Martens)KAYA Oguzhan (Knoblich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HUTH Michelle (Leeb), RADHAKRISHNA PILLAI Balashankar (Brennecke), REN Kaike (Otsuka)Date: 2025-09-08, Time: 12:30:00, Speaker: HUTH Michelle (Leeb)RADHAKRISHNA PILLAI Balashankar (Brennecke)REN Kaike (Otsuka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GONZALEZ ALVARADO Maria Nazareth (Grade), KASHKO Nataliia (Matos), OBERHUEMER Michael (Leeb)Date: 2025-09-15, Time: 12:30:00, Speaker: GONZALEZ ALVARADO Maria Nazareth (Grade)KASHKO Nataliia (Matos)OBERHUEMER Michael (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joao Matos, Peter Schlögelhofer Katja WassmannDate: 2025-09-18, Time: 11:00:00, Speaker: Katja Wassmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institute Jacques Monod, Host: Joao Matos, Peter Schlögelhofer
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KONSTANTINOU Andri (Obenauf), HARTMANN Felix (Matos), JENTOFT Ida (Pauli)Date: 2025-09-22, Time: 12:30:00, Speaker: KONSTANTINOU Andri (Obenauf)HARTMANN Felix (Matos)JENTOFT Ida (Pauli), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alex Stark Fabian TheisDate: 2025-09-25, Time: 11:00:00, Speaker: Fabian Theis, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Computational Health Center, Helmholtz Munich, Host: Alex Stark
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PAVLOVA Anzhela (Matos), SHARMA Sanskriti (Ellis), VETRANO Pamela (Ramundo)Date: 2025-09-29, Time: 12:30:00, Speaker: PAVLOVA Anzhela (Matos)SHARMA Sanskriti (Ellis)VETRANO Pamela (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WIGHARD Sara Sylvia (Burga), PRLESI Ines (Gerlich), BECHT Nanette (Gaidt)Date: 2025-10-06, Time: 12:30:00, Speaker: WIGHARD Sara Sylvia (Burga)PRLESI Ines (Gerlich)BECHT Nanette (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Elly Tanaka Alexander van OudenaardenDate: 2025-10-09, Time: 11:00:00, Speaker: Alexander van Oudenaarden, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Elly Tanaka
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PIECH Lucas (Leonard), NABIH MOSTAFA Amena (Pauli), GREMMELMAIER Constanze (Plaschka)Date: 2025-10-13, Time: 12:30:00, Speaker: PIECH Lucas (Leonard)NABIH MOSTAFA Amena (Pauli)GREMMELMAIER Constanze (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Andrea Pauli Anne BrunetDate: 2025-10-16, Time: 11:00:00, Speaker: Anne Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Stanford University, Host: Andrea Pauli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KYPRIANOU Christos (Rivron), MOYSIADOU Sofia (Obenauf), GALLAGE CHANUKA POSHITHA Fernando (Zimmer)Date: 2025-10-20, Time: 12:30:00, Speaker: KYPRIANOU Christos (Rivron)MOYSIADOU Sofia (Obenauf)GALLAGE CHANUKA POSHITHA Fernando (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz, Martin Leeb Aydan Bulut-KarsliogluDate: 2025-10-23, Time: 11:00:00, Speaker: Aydan Bulut-Karslioglu, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MPI Berlin, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
12:30 IMP Lecture Hall None IAROVENKO Svetlana (Brennecke), HIDAKA Takuya (Gerlich)Date: 2025-10-27, Time: 12:30:00, Speaker: IAROVENKO Svetlana (Brennecke)HIDAKA Takuya (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall David Haselbach Kresten Lindorff-LarssenDate: 2025-10-30, Time: 11:00:00, Speaker: Kresten Lindorff-Larssen, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: David Haselbach
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIAS Ana Beatriz (Slade), VALERI Erika (Gaidt), CHATZIANGELOU Myrto (Stark)Date: 2025-11-03, Time: 12:30:00, Speaker: DIAS Ana Beatriz (Slade)VALERI Erika (Gaidt)CHATZIANGELOU Myrto (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None FRASZ Lisa-Maria (Obenauf), MYLARSHCHIKOV Dmitry (Gerlich), SAHA Sayantan (Huis)Date: 2025-11-10, Time: 12:30:00, Speaker: FRASZ Lisa-Maria (Obenauf)MYLARSHCHIKOV Dmitry (Gerlich)SAHA Sayantan (Huis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz, Martin Leeb Jamie HackettDate: 2025-11-13, Time: 11:00:00, Speaker: Jamie Hackett, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: EMBL Rome, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PITASI Mattia (Leeb), FORBES Rebecca (Görke), MATURI Samuele (Grade)Date: 2025-11-17, Time: 12:30:00, Speaker: PITASI Mattia (Leeb)FORBES Rebecca (Görke)MATURI Samuele (Grade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
To be annouced
11:00 IMBA/GMI Lecture Hall Marco Hein Noam Stern-GinossarDate: 2025-11-20, Time: 11:00:00, Speaker: Noam Stern-Ginossar, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute of Science, Host: Marco Hein
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HEINZL Monika (Stark), MARTZIOS Panagiotis (Huis), BASTOS VENTURA Guilherme (Pinheiro)Date: 2025-11-24, Time: 12:30:00, Speaker: HEINZL Monika (Stark)MARTZIOS Panagiotis (Huis)BASTOS VENTURA Guilherme (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None JONASSON Mattias (Bücker), KNAUDT Hannah (Haselbach)Date: 2025-12-01, Time: 12:30:00, Speaker: JONASSON Mattias (Bücker)KNAUDT Hannah (Haselbach), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BERKUN Kathleen (Hallacli), , GRAF Max (Plaschka)Date: 2025-12-15, Time: 12:30:00, Speaker: BERKUN Kathleen (Hallacli)GRAF Max (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BOHAUMILITZKY Lena (Pinheiro), SPEICHERT Katarzyna (Martens), NG Hing Pan (Ma)Date: 2026-01-12, Time: 12:30:00, Speaker: BOHAUMILITZKY Lena (Pinheiro)SPEICHERT Katarzyna (Martens)NG Hing Pan (Ma), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None FARAWAY Rupert (Plaschka), ETHIER Elizabeth (Hallacli), RAINA Shiviya (Dammermann)Date: 2026-01-19, Time: 12:30:00, Speaker: FARAWAY Rupert (Plaschka)ETHIER Elizabeth (Hallacli)RAINA Shiviya (Dammermann), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WULF Paul Oliver (Tessmar), MISHRA Sachin (Stark), OGZUC Olivia (Querques)Date: 2026-01-26, Time: 12:30:00, Speaker: WULF Paul Oliver (Tessmar)MISHRA Sachin (Stark)OGZUC Olivia (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None COSTANTINI Elena (Tanaka), VIOHL Niklas (Köhler), LEON-RUIZ Jesus (Dolan)Date: 2026-02-02, Time: 12:30:00, Speaker: COSTANTINI Elena (Tanaka)VIOHL Niklas (Köhler)LEON-RUIZ Jesus (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None MIOCIC-STOSIC Fran (Zagrovic), BELL Caelan (Gerlich), KLEINWAECHTER Ava (Slade)Date: 2026-02-09, Time: 12:30:00, Speaker: MIOCIC-STOSIC Fran (Zagrovic)BELL Caelan (Gerlich)KLEINWAECHTER Ava (Slade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HOFMANN Maura (Van der Veeken), SEN Zeynep Begüm (Ma), ZEN PETISCO FIORE Ana Paula (Urban)Date: 2026-02-16, Time: 12:30:00, Speaker: HOFMANN Maura (Van der Veeken)SEN Zeynep Begüm (Ma)ZEN PETISCO FIORE Ana Paula (Urban), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None JANKOWSKA Julia (Ameres), DOCAVO GARCIA Antonio (Jachowicz), HAONAN Bao (Dolan)Date: 2026-02-23, Time: 12:30:00, Speaker: JANKOWSKA Julia (Ameres)DOCAVO GARCIA Antonio (Jachowicz)HAONAN Bao (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RUSSETT Colleen (Berger), ZEILER Christine (Kovarik), HOLLAUS David (Gaidt)Date: 2026-03-02, Time: 12:30:00, Speaker: RUSSETT Colleen (Berger)ZEILER Christine (Kovarik)HOLLAUS David (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GUZMAN PEREZ Sebastian (Martinez), ROFFAY Chloe (Pinheiro), BHARDWAJ Vishakha (Schlögelhofer)Date: 2026-03-09, Time: 12:30:00, Speaker: GUZMAN PEREZ Sebastian (Martinez)ROFFAY Chloe (Pinheiro)BHARDWAJ Vishakha (Schlögelhofer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
