Ever since the early days of molecular biology, researchers have been speculating about the driving forces that have led to the establishment of the genetic code. It is an intriguingly simple set of rules that allows cells to produce messenger RNAs that can be translated into proteins. The code is based on only 4 nucleotides, represented by the letters A, G, C, T, or U in RNA. In genes they are arranged in sequences and read in steps of three, called a triplet or codon. Each codon represents one amino acid, or contains the information to stop translation of the message into proteins. Fascinatingly, the origin of the genetic code remains mysterious. An mRNA-protein complementarity hypothesis, recently proposed by the lab of Bojan Zagrovic, aims to shed light on this long-standing puzzle. We talked with Bojan about the hypothesis and how the consortium involved in the Volkswagen foundation supported project will combine their approaches to try to answer a long-standing and fundamental question about life.
Bojan, why is the origin of the universal genetic code such an important question?
The answer is twofold. The first one has to do with its universality. There are many phenomena in biology that are system specific, but the genetic code is universally conserved, with only minor exceptions seen in some organisms. Therefore, how it came to be is an important question. The second reason is that the genetic code provides the central contact point between the world of nucleic acids and the world of polypeptides, two of arguably the most important biopolymers in all of biology.
There are a few theories trying to explain the origin of the universal genetic code. What is the stereochemical hypothesis and why did you choose to scrutinize it further?
The important question here is: why does a certain triplet code for a certain amino acid? The stereochemical hypothesis, proposed by Carl Woese and others a long time ago, suggests that the simplest way to establish this connection is following the direct interaction preferences between codons and the amino acids they encode. The problem is that the experimental evidence in this direction has remained inconclusive. The interactions are weak: a triplet may bind a certain amino acid, but could also bind other ones. However, most studies have only dealt with individual codons and amino acids. But, what if you connected multiple codons and amino acids? If you think about Velcro, for example: you have two sets of brushes and the individual hairs in those brushes have a very weak affinity for each other. But, if you put many of them next to each other, the Velcro sticks together. We now suggest that such an amplification could also be seen if one investigates the connection between chains of codons and chains of amino acids, or in other words, mRNAs and entire proteins. Simply put, mRNAs and the proteins they encode could be physiochemically complementary to each other and bind in a co-aligned fashion, especially if unstructured. Our preliminary findings point in this direction.
It is known that there are certain specific interactions between nucleic acids and proteins. RNA binding proteins, for example, can interact with and often modify RNA. What are the implications of your hypothesis in this context?
On the one hand, our hypothesis suggests that under some circumstances most proteins may actually have RNA-binding capabilities and that binding may represent the essence of the RNA-protein relationship. It also means that we could potentially understand all of RNA- protein interactions through the prism of the genetic code. The genetic code is basically a coding table that tells us how translation works. If we find evidence for the complementarity hypothesis, one could actually flip this statement around: we could use the genetic code to understand binding in general. This means, in theory, that we could predict who binds to whom, why, with what affinity and so on. It is almost like the genetic code could be seen as a Rosetta Stone, a dictionary, for understanding RNA-protein interactions in general.
You mentioned that the experimental evidence for the hypothesis is inconclusive. Can you explain how you are going to test the hypothesis more conclusively?
The essence of our hypothesis is that a large number of proteins bind their own mRNA. Therefore, the lab of Zoya Ignatova will be testing this hypothesis on a cell-wide, proteomic level. On the other hand, Markus Zweckstetter will focus on a particular protein, RNA polymerase II, one of the most important enzymes in the cell, and its interactions with different RNAs. By doing so, we will combine a large-scale approach with a detailed, mechanistic approach to see whether the data support our hypothesis. I am very proud and honored to be collaborating with such fantastic groups.
And what will be the role of your lab in the project?
My lab will provide the connection between the two experimental sides. We will provide computer simulations as well as theoretical, structural, and bioinformatic analysis. And, we will, in a way, be in charge of guiding the experimental work to test a particular set of implications of the hypothesis.
The whole project relates to a central paradigm in all of biology. We talked about the effects on RNA binding proteins specifically - what would be the implications on a larger scale if the hypothesis turns out to be true?
The concept of physicochemical complementarity is one of the strongest explanatory principles in all of biology – think, for example, of the complementarity between the two strands of DNA, which underlies gene duplication, or the connection of antibody-antigen that is at the heart of our immune system. It would be a big step forward if one could show that the two key players in all of biology, proteins and their mRNAs, are under some circumstances also complementary to each other.
About the Volkswagen Foundation: https://www.volkswagenstiftung.de/en
AI for in vivo studies: Advantages of continuous monitoring of several animals in their home cage, without the use of RFID
Date: 2024-07-11, Time: 10:00:00, Speaker: Noah Weber, Location: IMP Seminar Room 5.058, Type: Impromptu Seminar, Institute: Olden Labs, Host: Sylvia Badurek - VBCF
Monday Seminar (Internal)
Date: 2024-07-15, Time: 12:30:00, Speaker: ZEILER Christina (Kovarik)BHARDWAJ Vishakha (Schlögelhofer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
How the apoptotic factor Apaf1 behaves in cells during cell death
Date: 2024-07-18, Time: 11:00:00, Speaker: Wanda Kukulski, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Bern, Host: Elif Karagöz
Monday Seminar (Internal)
Date: 2024-07-22, Time: 12:30:00, Speaker: GUZMAN PEREZ Sebastian (Martinez)LITTLEBOY Jamie (Knoblich)ZMAJKOVIC Jakub (Zuber), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-07-29, Time: 12:30:00, Speaker: MAURER Eric (Peters)DOCAVO GARCIA Antonio (Jachowicz)BABADEI Olga (Decker), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-08-05, Time: 12:30:00, Speaker: DEL CHIARO Alessia (Dagdas)HUETTER Christiane (Menche)SHETTY Kavya (Hein), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
An alternative mechanism to form an organizing center in mouse neural tube organoids
Date: 2024-08-08, Time: 15:00:00, Speaker: Teresa Krammer, Location: IMBA/GMI Lecture Hall, Type: PhD Defense, Institute: IMBA - Tanaka Lab, Host: None
Advanced Concepts of Super-Resolution Fluorescence Microscopy
Date: 2024-08-09, Time: 10:00:00, Speaker: Jörg Enderlein, Location: IMP Lecture Hall, Type: IMP Impromptu Seminar, Institute: Georg August University, Host: Francisco Balzarotti
Monday Seminar (Internal)
Date: 2024-08-12, Time: 12:30:00, Speaker: ANTONIOLI Sumire (Leonard)EMTENANI Shamsi(Knoblich)SANDRU Ana Maria (Baccarini), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-08-19, Time: 12:30:00, Speaker: BENEDUM Johannes (Slade)KALIS Robert (Zuber)PATEL Rajvi (Matos), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-08-26, Time: 12:30:00, Speaker: JANSEN Ralf (Brennecke)SILVA Raquel (Foisner)BASSAT Elad (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-09-02, Time: 12:30:00, Speaker: SCHAAR Benjamin (Zimmer)IGOLKINA Anna (Nordborg)PROTSENKO Liudmila (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Striking physiology and cell biology of (marine) environmental microorganisms
Date: 2024-09-03, Time: 11:30:00, Speaker: Ralf Rabus, Location: Max Perutz Labs SR 1 (6th floor), Type: New Developments in Chromosome Biology, Institute: ICBM, Carl von Ossietzky Universität Oldenburg, Host: Kristin Tessmar-Raible
Title to be announced
Date: 2024-09-05, Time: 11:00:00, Speaker: Alexander Van Oudenaarden, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Daniel Gerlich
Monday Seminar (Internal)
Date: 2024-09-09, Time: 12:30:00, Speaker: STUART Hannah (Tanaka)ROVERA Emanuele (Zuber)KLOSS Linda (Technau), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Mechanisms controlling maintenance of cohesin dependent loops
Date: 2024-09-10, Time: 11:30:00, Speaker: Frederic Beckouet, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: Toulouse Centre de Biologie Intégrative, Host: Franz Klein
Title to be announced
Date: 2024-09-12, Time: 11:00:00, Speaker: Elcin Ünal, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: UC Berkeley, Host: Silvia Ramundo, Fred Berger
Monday Seminar (Internal)
Date: 2024-09-16, Time: 12:30:00, Speaker: WUN Cheuk Ling (Ramundo)MÜLLER Marlene (Rivron)RAUSCHMEIER Rene (Van der Veeken), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-09-19, Time: 11:00:00, Speaker: Noam Stern-Ginossar, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute of Science, Host: Marco Hein
Monday Seminar (Internal)
Date: 2024-09-23, Time: 12:30:00, Speaker: ESTIVILL I CAPARROS Guillem (Obenauf)VOJTEK Matus (Stark)DA COSTA Barbara (Berger), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-09-26, Time: 11:00:00, Speaker: Maria Mota, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lisbon, Host: Joao Matos
Title to be announced
Date: 2024-09-27, Time: 11:00:00, Speaker: Deborah Bourc'his, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: Institut Curie, Host: Julius Brennecke
Monday Seminar (Internal)
Date: 2024-09-30, Time: 12:30:00, Speaker: JÄGER Christina (Van der Veeken)SHUKLA Vikas (Berger)RODRIGUEZ TERRONES Diego (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-10-07, Time: 12:30:00, Speaker: KANNO Tatsuo (Berger)SCHIMMER Clara (Ellis)DE SANTIS Martina (Rivron), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-10-10, Time: 11:00:00, Speaker: Cedric Blanpain, Location: , Type: , Institute: Universite Libres Bruxelles, Host: Stephanie Ellis
Monday Seminar (Internal)
Date: 2024-10-14, Time: 12:30:00, Speaker: GAO Peng (Dagdas)HANDLER Dominik (Brennecke)FRIDRICH Arie (Berger), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-10-17, Time: 11:00:00, Speaker: Ralf Jungmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: LMU, MPI, Host: Alex Stark, Francisco Balzarotti
Monday Seminar (Internal)
Date: 2024-10-21, Time: 12:30:00, Speaker: MILOJKOVIC Lidija (Urban)SPENCER Victoria (Dolan)AUGUSTO Pedro (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-10-24, Time: 11:00:00, Speaker: Andrea Ablasser, Location: IMP Lecture Hall, Type: VBC Regular Seminar, Institute: EPFL, Host: Moritz Gaidt
Monday Seminar (Internal)
Date: 2024-10-28, Time: 12:30:00, Speaker: GOMEZ SEGALAS Alba (Balzarotti)KLEINFERCHER Sebastian (Stark)PRADHAN Saurabh (Rivron), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-11-04, Time: 12:30:00, Speaker: SCHEPERS Sandra (Knoblich)BUSETTO Virginia (Falk)DMITRIEV Vladimir (Goloborodko), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
VBC PhD Symposium
Date: 2024-11-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2024-11-11, Time: 12:30:00, Speaker: GARCIA GALLARDO Maria (Bücker)HARVEY Zachary (Berger)SAKALLI Enes (Von Haeseler,Menche), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-14, Time: 11:00:00, Speaker: Benoit Bruneau, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Gladstone Institute of Cardiovascular Disease, UCSF, Host: Sasha Menjdan
Title to be announced
Date: 2024-11-18, Time: 11:00:00, Speaker: Lacramioara Bintu, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: Stanford University, Host: Alex Stark
Monday Seminar (Internal)
Date: 2024-11-18, Time: 12:30:00, Speaker: FESSELET Jeanne (Kovarik)PAPAREDDY Ranjith (Dagdas)SHEN Jingyi (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-11-21, Time: 11:00:00, Speaker: Martin Jinek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Zurich, Host: Irma Querques
Monday Seminar (Internal)
Date: 2024-11-25, Time: 12:30:00, Speaker: BOREIKAITE Vytaute (Plaschka)SRINIVASAN Navaneeth (Peters)DODOMANI Ananya (Campbell), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-28, Time: 18:00:00, Speaker: David Baker, Location: Zoom, Type: VBC Regular Seminar via Zoom, Institute: UW Dept. of Biochemistry, Host: Alwin Köhler
Monday Seminar (Internal)
Date: 2024-12-02, Time: 12:30:00, Speaker: SOMMER Theresa (Rivron)MAIR Zahar (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-12-05, Time: 11:00:00, Speaker: Ian Hickson, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Joao Matos
Monday Seminar (Internal)
Date: 2024-12-09, Time: 12:30:00, Speaker: BREHM Martin (Falk)PLATZER Sebastian (Hein)RAFANEL Baptiste (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-12-12, Time: 11:00:00, Speaker: Stephen West, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: The Francis Crick Institute, Host: Joao Matos
Monday Seminar (Internal)
Date: 2024-12-16, Time: 12:30:00, Speaker: DAHAN Tal (Nordborg)CHUGUNOVA Anastasia (Pauli)VON WIREN Julius (Kovarik), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-01-09, Time: 11:00:00, Speaker: Uri Ben-David, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Tel Aviv University, Host: Anna Obenauf
Monday Seminar (Internal)
Date: 2025-01-13, Time: 12:30:00, Speaker: KRASNOVID Filipp (Mari-Ordonez)ROTHE Patricia (Plaschka)KROGULL Daniel (Burga), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-01-20, Time: 12:30:00, Speaker: VICIC Ziga (Jachowicz)GRÜNEWALD Jakob (Obenauf)MANOLOVA Toni (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2025-01-23, Time: 11:00:00, Speaker: Anne Bertolotti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MCR Laboratory of Molecular Biology, Host: Egon Ogris
Monday Seminar (Internal)
Date: 2025-01-27, Time: 12:30:00, Speaker: SCARAMUZZA Federico (Tessmar) WALTER Mateusz (Querques)WILLIAMS Thomas (Clausen), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-02-03, Time: 12:30:00, Speaker: CRUZ Joseph (Gerlich)GHEORGHITA Andreea (Clausen)GALUSKA Philipp (Djinovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-02-10, Time: 12:30:00, Speaker: GRIGOREVA Elizaveta (Nordborg)KOHOUTKOVA Eliska (Clausen)STEINACKER Thomas (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-02-13, Time: 11:00:00, Speaker: Jeff Boeke, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: NYU Langdone Health, Host: Fred Berger
Monday Seminar (Internal)
Date: 2025-02-17, Time: 12:30:00, Speaker: RAFFL Gerald (Ameres)VULIN Milica (Obenauf)FISCHER Andre (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-02-24, Time: 12:30:00, Speaker: BAYERL Jonas (Zuber)ZABOLOCKI Michael (Knoblich)EDER Stephanie (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-02-27, Time: 11:00:00, Speaker: Cedric Feschotte, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Cornell University, Host: Joanna Jachowicz
Monday Seminar (Internal)
Date: 2025-03-03, Time: 12:30:00, Speaker: KROETENHEERDT Eva (Leonard)RÖHSNER Josef (Pauli)RIABOV Daria (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-10, Time: 12:30:00, Speaker: CHO Chung Hyun (Berger)SEIDL Carina (Tanaka)MIGOTTI Mario (Konrat), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-17, Time: 12:30:00, Speaker: CHEN Shenzhi (Stark)BINDL Michael (Leeb)JÄGER Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-03-20, Time: 11:00:00, Speaker: Geert Kops, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Joao Matos
Monday Seminar (Internal)
Date: 2025-03-24, Time: 12:30:00, Speaker: MAYA Juan (Balzarotti)DOSA Anna (Clausen)KOBER Julia (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-03-27, Time: 11:00:00, Speaker: Martin Beck, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Biophysics, Host: Alwin Köhler
Monday Seminar (Internal)
Date: 2025-03-31, Time: 12:30:00, Speaker: HOLZER Elisabeth (Martens)THEMANN Jan (Knoblich)GROSS Angelina (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-07, Time: 12:30:00, Speaker: GROH Roan (Dagdas)CHAO Victor (Huis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-14, Time: 12:30:00, Speaker: OKUN Anastasia (Karagöz)COLLISON Robert (Ramundo)WELZL Paul (Balzarotti/Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-04-24, Time: 11:00:00, Speaker: Maria Cristina Gambetta, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lausanne, Host: Anton Goloborodko
Monday Seminar (Internal)
Date: 2025-04-28, Time: 12:30:00, Speaker: SUWITA Johannes (Pauli)GRABARCZYK Daniel (Clausen)PANDA Aswini (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-05, Time: 12:30:00, Speaker: KIM Olena (Knoblich)JOB Nikhil (Dolan)ADELMANN Leonie (Raible), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Microsymposium on Small RNA Biology
Date: 2025-05-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2025-05-12, Time: 12:30:00, Speaker: SCIBISZ Grzegorz (Karagöz)VAN GENDEREN Emiel (Rivron)BOZKURT Miray (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-05-15, Time: 11:00:00, Speaker: Chuna Ram Choudhary, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Alex Stark
Monday Seminar (Internal)
Date: 2025-05-19, Time: 12:30:00, Speaker: POTTENDORFER Elisabeth (Obenauf)WALLNER Eva-Sophie (Dolan)BECKER Moritz (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-05-22, Time: 11:00:00, Speaker: Manuel Leonetti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: CZ Biohub San Francisco, Host: Elif Karagöz
Monday Seminar (Internal)
Date: 2025-05-26, Time: 12:30:00, Speaker: DIMITROVA Polina (Van der Veeken)STRAVS Ana (Knoblich)SCHÖNLEIN Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-02, Time: 12:30:00, Speaker: SABATH Kevin (Plaschka/Stark)MANCHENO JUNCOSA Estela (Mendjan)HORENKAMP Simone (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-16, Time: 12:30:00, Speaker: BERGER Sonja (Goloborodko)KOWALD Saskia (Gaidt)KAPRAL Thomas (Zagrovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-23, Time: 12:30:00, Speaker: BUCHERON Chloe (Menche)KRUMWIEDE Luisa (Gaidt)PACHANO Tomas (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-06-26, Time: 11:00:00, Speaker: Nikhil Joshi, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Yale University, Host: Joris Van der Veeken
Monday Seminar (Internal)
Date: 2025-06-30, Time: 12:30:00, Speaker: SCHINDLER Lukas (Schlögelhofer)MANDLBURGER Nikolaus (Stark)OTTO Magdalena (Leonard), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-07-03, Time: 11:00:00, Speaker: Matthias Mann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max-Planck Institute of Biochemistry, Host: Marco Hein
Monday Seminar (Internal)
Date: 2025-07-07, Time: 12:30:00, Speaker: TRUS Palina (Peters)KOBAKHIDZE George (Dong)KONGSTED Thea (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-07-10, Time: 11:00:00, Speaker: Simon Alberti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: TU Dresden, Host: Erinc Hallacli
Monday Seminar (Internal)
Date: 2025-07-14, Time: 12:30:00, Speaker: RUSCH Emma (Golobordko)VELIKOV Daniel (Matos)VOGEL Alexander (Clausen/Yudushkin), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-21, Time: 12:30:00, Speaker: ANGELOPOULOU Eleni (Ellis)SCHAFFER Petra (Grade)RAMIREZ America (Köhler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-28, Time: 12:30:00, Speaker: DIMITRIADI Anna (Mendjan)LEITNER Moritz (Martinez)RAUH Felix (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-04, Time: 12:30:00, Speaker: LI Wenxin (Zimmer)FISCHER Felix (Zagrovic)ABESAMIS Kim Ivan (Dong), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-11, Time: 12:30:00, Speaker: KLEIFELD Justus (Urban)MCATEER Tara (Pinheiro)BHATTACHARYA Mrinnanda (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-18, Time: 12:30:00, Speaker: BELL Lillie (Clausen)MIHAILOVIC Milica (Karagöz)GUYNES Keroshini (Jachowicz), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-25, Time: 12:30:00, Speaker: BOHL VIALLEFONT Gregoire (Nordborg)MARCHIORI Elisa (Van der Veeken)JAHNEL Stefan (Mendjan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-01, Time: 12:30:00, Speaker: KIRCHGATTERER Paul (Gaidt)ACHLEITNER Sonja (Martens)KAYA Oguzhan (Knoblich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-08, Time: 12:30:00, Speaker: HUTH Michelle (Leeb)RADHAKRISHNA PILLAI Balashankar (Brennecke)REN Kaike (Otsuka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-15, Time: 12:30:00, Speaker: GONZALEZ ALVARADO Maria Nazareth (Grade)KASHKO Nataliia (Matos)OBERHUEMER Michael (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-09-18, Time: 11:00:00, Speaker: Katja Wassmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institute Jacques Monod, Host: Joao Matos, Peter Schlögelhofer
Title to be announced
Date: 2025-10-16, Time: 11:00:00, Speaker: Anne Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Stanford University, Host: Andrea Pauli
Title to be announced
Date: 2025-10-30, Time: 11:00:00, Speaker: Kresten Lindorff-Larssen, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: David Haselbach