A major evolutionary conserved mechanism driving MDR phenomena is the activation of membrane proteins of the so-called ABC transporter protein family. For example, the ABCG2 transporter mediates the cellular expulsion of many drugs, thus rendering tumor cells or infectious pathogens resistant to treatment, eventually leading to therapeutic failure. MDR has been a major clinical concern, also because it has been dramatically increasing over the past years. Hence, new therapeutic approaches are needed to evade MDR and to restore efficient drug treatments.
Research Gaps hinder drug development
The molecular mechanism by which ABC membrane transporters operate, have remained ill-posed for many years. This has been hampering the development of drugs that would avoid MDR. Importantly, human ABC transporters such as ABCG2 also play essential physiological roles in the detoxification of unwanted toxic compounds, metabolites or environmental toxins from liver, breast, placenta, intestine or blood brain barrier tissues. Blocking of Multidrug Resistance aims to restore high intracellular drug concentrations to ensure therapeutic responses. However, a complete MDR inhibition is likely to suffer from severe side effects and increased drug toxicity, since physiological detoxification is not working properly. The research group of Karl Kuchler at the Max Perutz Labs Vienna exploited an interdisciplinary cooperation with the computational biologist Thomas Stockner from the Medical University of Vienna, to delineate the mechanism by which the human ABCG2 transporter mediates MDR.
ABCG2 works like a peristaltic pump
The study in Nature Communications reveals that the three-dimensional shape of ABCG2 looks like a peristaltic pump that contains a sealed but flexible valve separating two cavities in the transporter core. Both cavities are connected by a central channel, through which drugs are expelled from the inside to the outside of cells across the cell surface. Importantly, the opening of the valve and drug extrusion is controlled by a lid-like roof that covers the top of the ABCG2 pump. The groups used computational models in combination with experimental testing of genetically altered ABCG2 variants, to show how the lid controls valve opening during drug transport. The communicating cavities of alternating sizes form a central channel to enable drug transport out of cells. Moreover, the study identifies the dynamic interplay of regions within the ABCG2 roof, which are also critical for drug recognition and export. Hence, ABCG2 is a peristaltic pump that operates in a repetitive cycle that is fueled by cellular energy.
Amino acid residues could be therapeutically targeted
Remarkably, several amino acid residues that are essential for ABCG2 pump function are located in the lid and in the valve, suggesting that these residues could be amenable to developing novel drugs or antibodies that can partially block detrimental MDR phenotypes to ABCG2 activities observed. The first author of the study, Narakorn Khunweeraphong, is excited about the scope of the results: “It is so thrilling that we now better understand the mechanisms ABCG2 uses to cause MDR”. Karl Kuchler adds: “The knowledge about dynamic structural changes in ABCG2 may pave the way to develop novel immunological therapeutics that enable a specific and partial block of ABCG2 to activity levels observed in normal cells, without compromising physiological detoxification”.
Original Publication:
The ABCG2 multidrug transporter is a pump gated by a valve and an extracellular lid. Narakorn Khunweeraphong, Daniel Szöllősi, Thomas Stockner & Karl Kuchler. Nature Communications, 2019
Structure and Dynamics of the envelope glycoprotein of HIV-1 during Fusion
15:00
Lecture Hall B, VBC5 & Zoom
Thomas Juffmann
Sergi Padilla-ParraDate: 2025-01-09, Time: 15:00:00, Speaker: Sergi Padilla-Parra, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: King's College London, Host: Thomas Juffmann
Cancer aneuploidy: From selection pressures to cellular vulnerabilities
11:00 IMBA/GMI Lecture Hall Anna Obenauf Uri Ben-DavidDate: 2025-01-09, Time: 11:00:00, Speaker: Uri Ben-David, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Tel Aviv University, Host: Anna Obenauf
Monday Seminar (Internal)
12:30 IMP Lecture Hall KRASNOVID Filipp (Mari-Ordonez), ROTHE Patricia (Plaschka), KROGULL Daniel (Burga)Date: 2025-01-13, Time: 12:30:00, Speaker: KRASNOVID Filipp (Mari-Ordonez)ROTHE Patricia (Plaschka)KROGULL Daniel (Burga), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
The hidden gems of antiviral immune systems in bacteria
11:00 IMBA/GMI Lecture Hall Irma Querques Stan BrounsDate: 2025-01-16, Time: 11:00:00, Speaker: Stan Brouns, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Delft University of Technology, Host: Irma Querques
Monday Seminar (Internal)
12:30 IMP Lecture Hall VICIC Ziga (Jachowicz), GRÜNEWALD Jakob (Obenauf), MANOLOVA Toni (Falk)Date: 2025-01-20, Time: 12:30:00, Speaker: VICIC Ziga (Jachowicz)GRÜNEWALD Jakob (Obenauf)MANOLOVA Toni (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Deriving a genetic regulatory network from an optimization principle
14:00 Lecture Hall B, VBC5 & Zoom Bojan Zagrovic Gasper TkacikDate: 2025-01-23, Time: 14:00:00, Speaker: Gasper Tkacik, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: ISTA, Host: Bojan Zagrovic
Title to be announced
11:00 UBB - Lecture Hall 2 & Zoom Hayk Palabikyan Anais CarioDate: 2025-01-23, Time: 11:00:00, Speaker: Anais Cario, Location: UBB - Lecture Hall 2 & Zoom, Type: DOME Lecture Series, Institute: French National Centre for Scientific Research, Host: Hayk Palabikyan
Title to be announced
11:00 IMBA/GMI Lecture Hall Egon Ogris Anne BertolottiDate: 2025-01-23, Time: 11:00:00, Speaker: Anne Bertolotti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MCR Laboratory of Molecular Biology, Host: Egon Ogris
Size Matters: The unique exocytosis mechanism of large secretory vesicles
10:00 IMBA/GMI Lecture Hall Andi Pauli Ori AvinoamDate: 2025-01-27, Time: 10:00:00, Speaker: Ori Avinoam, Location: IMBA/GMI Lecture Hall, Type: IMP Impromptu Seminar, Institute: Weizmann Institute, Host: Andi Pauli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WILLIAMS Thomas (Clausen), SCARAMUZZA Federico (Tessmar), WALTER Mateusz (Querques)Date: 2025-01-27, Time: 12:30:00, Speaker: WILLIAMS Thomas (Clausen)SCARAMUZZA Federico (Tessmar)WALTER Mateusz (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Decidualisation of human endometrium: from evolutionary insights to novel mechanisms of disease
13:15 UBB - Lecture Hall 1 Mihaela Pavlicev Jan BrosensDate: 2025-01-28, Time: 13:15:00, Speaker: Jan Brosens, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: University of Warwick, Host: Mihaela Pavlicev
Design of New Protein Functions Using Deep Learning
18:00 Zoom Alwin Köhler David BakerDate: 2025-01-29, Time: 18:00:00, Speaker: David Baker, Location: Zoom, Type: VBC Regular Seminar, Institute: University of Washington School, Host: Alwin Köhler
Deconstruction and reconstruction of signalosomes: towards a spatial logic of information transfer in cell signaling
14:00 Lecture Hall B, VBC5 & Zoom Ivan Yudushkin Marcus TaylorDate: 2025-01-30, Time: 14:00:00, Speaker: Marcus Taylor, Location: Lecture Hall B, VBC5 & Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Max Planck Institute for Infection Biology, Berlin, Host: Ivan Yudushkin
Reactive Tracers in Chemical Substances: Compound-specific Isotope Analysis to Characterize Transformation of Organic Compounds
12:00 Zoom Thilo Hofmann Martin ElsnerDate: 2025-01-30, Time: 12:00:00, Speaker: Martin Elsner, Location: Zoom, Type: CeMESS Lecture Series, Institute: Technical University of Munich, Host: Thilo Hofmann
Transposable elements in development and reprogramming
11:00 IMBA/GMI Lecture Hall Julius Brennecke Maria-Elena Torres-PadillaDate: 2025-01-30, Time: 11:00:00, Speaker: Maria-Elena Torres-Padilla, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Ludwig-Maximilians-University Munich, Host: Julius Brennecke
Monday Seminar (Internal)
12:30 IMP Lecture Hall CRUZ Joseph (Gerlich), GHEORGHITA Andreea (Clausen), GALUSKA Philipp (Djinovic)Date: 2025-02-03, Time: 12:30:00, Speaker: CRUZ Joseph (Gerlich)GHEORGHITA Andreea (Clausen)GALUSKA Philipp (Djinovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Deciphering driving forces of cell fate decision at single-cell resolution in time and space
11:00 GMI Orange Seminar Room Alex Stark Dominic GruenDate: 2025-02-04, Time: 11:00:00, Speaker: Dominic Gruen, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: University of Würzburg, Host: Alex Stark
Exploring dynamic regulation and function of the nuclear lamina
10:30 IMP Lecture Hall David Haselbach Abigail BuchwalterDate: 2025-02-05, Time: 10:30:00, Speaker: Abigail Buchwalter, Location: IMP Lecture Hall, Type: Impromptu Seminar, Institute: UCSF, Host: David Haselbach
Ectomycorrhizal fungi as drivers of forest ecosystem processes
12:00 UBB - Lecture Hall 2 & Zoom Mark Anthony Filipa CoxxDate: 2025-02-06, Time: 12:00:00, Speaker: Filipa Coxx, Location: UBB - Lecture Hall 2 & Zoom, Type: CeMESS Lecture Series, Institute: University of Manchester, Host: Mark Anthony
Title to be announced
11:00 IMBA/GMI Lecture Hall Fred Berger Thibaut BrunetDate: 2025-02-06, Time: 11:00:00, Speaker: Thibaut Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institut Pasteur, University Paris-Cite, Host: Fred Berger
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GRIGOREVA Elizaveta (Nordborg), KOHOUTKOVA Eliska (Clausen), STEINACKER Thomas (Gerlich)Date: 2025-02-10, Time: 12:30:00, Speaker: GRIGOREVA Elizaveta (Nordborg)KOHOUTKOVA Eliska (Clausen)STEINACKER Thomas (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Fred Berger Jeff BoekeDate: 2025-02-13, Time: 11:00:00, Speaker: Jeff Boeke, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: NYU Langdone Health, Host: Fred Berger
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RAFFL Gerald (Ameres), VULIN Milica (Obenauf), FISCHER Andre (Tanaka)Date: 2025-02-17, Time: 12:30:00, Speaker: RAFFL Gerald (Ameres)VULIN Milica (Obenauf)FISCHER Andre (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Defining the autism cell phenotypic landscape
11:00 IMBA/GMI Lecture Hall Dea Slade Gaia NovarinoDate: 2025-02-20, Time: 11:00:00, Speaker: Gaia Novarino, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: ISTA, Host: Dea Slade
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BAYERL Jonas (Zuber), ZABOLOCKI Michael (Knoblich), EDER Stephanie (Zimmer)Date: 2025-02-24, Time: 12:30:00, Speaker: BAYERL Jonas (Zuber)ZABOLOCKI Michael (Knoblich)EDER Stephanie (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz Cedric FeschotteDate: 2025-02-27, Time: 11:00:00, Speaker: Cedric Feschotte, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Cornell University, Host: Joanna Jachowicz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KROETENHEERDT Eva (Leonard), RÖHSNER Josef (Pauli), RIABOV Daria (Plaschka)Date: 2025-03-03, Time: 12:30:00, Speaker: KROETENHEERDT Eva (Leonard)RÖHSNER Josef (Pauli)RIABOV Daria (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz Zach SmithDate: 2025-03-06, Time: 11:00:00, Speaker: Zach Smith, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: MIT, Host: Joanna Jachowicz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None CHO Chung Hyun (Berger), SEIDL Carina (Tanaka), MIGOTTI Mario (Konrat)Date: 2025-03-10, Time: 12:30:00, Speaker: CHO Chung Hyun (Berger)SEIDL Carina (Tanaka)MIGOTTI Mario (Konrat), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Diana Pinheiro, Alex Stark Joaquina DelasDate: 2025-03-11, Time: 11:00:00, Speaker: Joaquina Delas, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: University College London, Host: Diana Pinheiro, Alex Stark
SY-Stem
Mar 12 - Mar 14 IMP Lecture Hall NoneDate: 2025-03-12, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None CHEN Shenzhi (Stark), BINDL Michael (Leeb), JÄGER Martin (Obenauf)Date: 2025-03-17, Time: 12:30:00, Speaker: CHEN Shenzhi (Stark)BINDL Michael (Leeb)JÄGER Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Unravelling the inner secrets of cells with live-cell super-resolution microscopy
10:00 Lecture Hall A, VBC 5 Jonas Ries Francesca BottanelliDate: 2025-03-19, Time: 10:00:00, Speaker: Francesca Bottanelli, Location: Lecture Hall A, VBC 5, Type: Impromptu Seminar, Institute: Freie Universität Berlin, Host: Jonas Ries
Title to be announced
11:00 IMBA/GMI Lecture Hall Joao Matos Geert KopsDate: 2025-03-20, Time: 11:00:00, Speaker: Geert Kops, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Joao Matos
Monday Seminar (Internal)
12:30 IMP Lecture Hall None MAYA Juan (Balzarotti), DOSA Anna (Clausen), KOBER Julia (Ramundo)Date: 2025-03-24, Time: 12:30:00, Speaker: MAYA Juan (Balzarotti)DOSA Anna (Clausen)KOBER Julia (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alwin Köhler Martin BeckDate: 2025-03-27, Time: 11:00:00, Speaker: Martin Beck, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Biophysics, Host: Alwin Köhler
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HOLZER Elisabeth (Martens), THEMANN Jan (Knoblich), GROSS Angelina (Dagdas)Date: 2025-03-31, Time: 12:30:00, Speaker: HOLZER Elisabeth (Martens)THEMANN Jan (Knoblich)GROSS Angelina (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Sebastian Falk Rotem SorekDate: 2025-04-03, Time: 11:00:00, Speaker: Rotem Sorek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute, Host: Sebastian Falk
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GROH Roan (Dagdas), CHAO Victor (Huis), KHANDEKAR Ameya (Ellis)Date: 2025-04-07, Time: 12:30:00, Speaker: GROH Roan (Dagdas)CHAO Victor (Huis)KHANDEKAR Ameya (Ellis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
"Tiles of Life" Symposium
Apr 10 - Apr 11 IMP Lecture Hall SMICH communityDate: 2025-04-10, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall , Type: Symposium, Institute: None, Host: SMICH community
Tiles of Life - Student Symposium
Apr 10 - Apr 11 IMP lecture hall, Vienna BioCenterThe symposium will explore the intricate "tiles" that form the vast and diverse fields of molecular biology and aims to foster discussions and inspire collaborations by bringing the “tiles of life” together. The program includes several talks by esteemed and international speakers sharing their latest findings to link the molecular mosaic of the cell - from structures to organisms. Additionally, we will highlight the research of the SMICH community on campus by complementing the program with student talks.
Monday Seminar (Internal)
12:30 IMP Lecture Hall None OKUN Anastasia (Karagöz), COLLISON Robert (Ramundo), WELZL Paul (Balzarotti/Plaschka)Date: 2025-04-14, Time: 12:30:00, Speaker: OKUN Anastasia (Karagöz)COLLISON Robert (Ramundo)WELZL Paul (Balzarotti/Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Anton Goloborodko Maria Cristina GambettaDate: 2025-04-24, Time: 11:00:00, Speaker: Maria Cristina Gambetta, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lausanne, Host: Anton Goloborodko
Title to be announced
10:30 IMP Seminar Room 1.014/16 Diana Pinheiro Takshi HiragiDate: 2025-04-25, Time: 10:30:00, Speaker: Takshi Hiragi, Location: IMP Seminar Room 1.014/16, Type: IMP Impromptu Seminar, Institute: Hubrecht Institute, Host: Diana Pinheiro
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SUWITA Johannes (Pauli), GRABARCZYK Daniel (Clausen), PANDA Aswini (Falk)Date: 2025-04-28, Time: 12:30:00, Speaker: SUWITA Johannes (Pauli)GRABARCZYK Daniel (Clausen)PANDA Aswini (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KIM Olena (Knoblich), JOB Nikhil (Dolan), ADELMANN Leonie (Raible)Date: 2025-05-05, Time: 12:30:00, Speaker: KIM Olena (Knoblich)JOB Nikhil (Dolan)ADELMANN Leonie (Raible), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Microsymposium on RNA Biology'
May 07 - May 09 IMP Lecture Hall NoneDate: 2025-05-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
EMBO meeting on RNA meets Protein decay
May 11 - May 14 IMP Lecture Hall NoneDate: 2025-05-11, Time: 14:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SCIBISZ Grzegorz (Karagöz), VAN GENDEREN Emiel (Rivron), BOZKURT Miray (Tanaka)Date: 2025-05-12, Time: 12:30:00, Speaker: SCIBISZ Grzegorz (Karagöz)VAN GENDEREN Emiel (Rivron)BOZKURT Miray (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alex Stark Chuna Ram ChoudharyDate: 2025-05-15, Time: 11:00:00, Speaker: Chuna Ram Choudhary, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Alex Stark
Monday Seminar (Internal)
12:30 IMP Lecture Hall None POTTENDORFER Elisabeth (Obenauf), WALLNER Eva-Sophie (Dolan), BECKER Moritz (Leeb)Date: 2025-05-19, Time: 12:30:00, Speaker: POTTENDORFER Elisabeth (Obenauf)WALLNER Eva-Sophie (Dolan)BECKER Moritz (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Elif Karagöz Manuel LeonettiDate: 2025-05-22, Time: 11:00:00, Speaker: Manuel Leonetti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: CZ Biohub San Francisco, Host: Elif Karagöz
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIMITROVA Polina (Van der Veeken), STRAVS Ana (Knoblich), SCHÖNLEIN Martin (Obenauf)Date: 2025-05-26, Time: 12:30:00, Speaker: DIMITROVA Polina (Van der Veeken)STRAVS Ana (Knoblich)SCHÖNLEIN Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SABATH Kevin (Plaschka/Stark), MANCHENO JUNCOSA Estela (Mendjan), HORENKAMP Simone (Tanaka)Date: 2025-06-02, Time: 12:30:00, Speaker: SABATH Kevin (Plaschka/Stark)MANCHENO JUNCOSA Estela (Mendjan)HORENKAMP Simone (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Julius Brennecke Stefan MundlosDate: 2025-06-12, Time: 11:00:00, Speaker: Stefan Mundlos, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max Planck Institute for Molecular Genetics, Host: Julius Brennecke
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BERGER Sonja (Goloborodko), KOWALD Saskia (Gaidt), KAPRAL Thomas (Zagrovic)Date: 2025-06-16, Time: 12:30:00, Speaker: BERGER Sonja (Goloborodko)KOWALD Saskia (Gaidt)KAPRAL Thomas (Zagrovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joris Van der Veeken Nikhil JoshiDate: 2025-06-18, Time: 11:00:00, Speaker: Nikhil Joshi, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Yale University, Host: Joris Van der Veeken
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BUCHERON Chloe (Menche), KRUMWIEDE Luisa (Gaidt), PACHANO Tomas (Stark)Date: 2025-06-23, Time: 12:30:00, Speaker: BUCHERON Chloe (Menche)KRUMWIEDE Luisa (Gaidt)PACHANO Tomas (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None SCHINDLER Lukas (Schlögelhofer), MANDLBURGER Nikolaus (Stark), OTTO Magdalena (Leonard)Date: 2025-06-30, Time: 12:30:00, Speaker: SCHINDLER Lukas (Schlögelhofer)MANDLBURGER Nikolaus (Stark)OTTO Magdalena (Leonard), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Marco Hein Matthias MannDate: 2025-07-03, Time: 11:00:00, Speaker: Matthias Mann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Max-Planck Institute of Biochemistry, Host: Marco Hein
Monday Seminar (Internal)
12:30 IMP Lecture Hall None TRUS Palina (Peters), KOBAKHIDZE George (Dong), KONGSTED Thea (Dolan)Date: 2025-07-07, Time: 12:30:00, Speaker: TRUS Palina (Peters)KOBAKHIDZE George (Dong)KONGSTED Thea (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Erinc Hallacli Simon AlbertiDate: 2025-07-10, Time: 11:00:00, Speaker: Simon Alberti, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: TU Dresden, Host: Erinc Hallacli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RUSCH Emma (Golobordko), VELIKOV Daniel (Matos), VOGEL Alexander (Clausen/Yudushkin)Date: 2025-07-14, Time: 12:30:00, Speaker: RUSCH Emma (Golobordko)VELIKOV Daniel (Matos)VOGEL Alexander (Clausen/Yudushkin), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None ANGELOPOULOU Eleni (Ellis), SCHAFFER Petra (Grade), RAMIREZ America (Köhler)Date: 2025-07-21, Time: 12:30:00, Speaker: ANGELOPOULOU Eleni (Ellis)SCHAFFER Petra (Grade)RAMIREZ America (Köhler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIMITRIADI Anna (Mendjan), LEITNER Moritz (Martinez), BRADAMANTE Gabriele (Biooptics)Date: 2025-07-28, Time: 12:30:00, Speaker: DIMITRIADI Anna (Mendjan)LEITNER Moritz (Martinez)BRADAMANTE Gabriele (Biooptics), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None LI Wenxin (Zimmer), FISCHER Felix (Zagrovic), ABESAMIS Kim Ivan (Dong)Date: 2025-08-04, Time: 12:30:00, Speaker: LI Wenxin (Zimmer)FISCHER Felix (Zagrovic)ABESAMIS Kim Ivan (Dong), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KLEIFELD Justus (Urban), MCATEER Tara (Pinheiro), BHATTACHARYA Mrinnanda (Zimmer)Date: 2025-08-11, Time: 12:30:00, Speaker: KLEIFELD Justus (Urban)MCATEER Tara (Pinheiro)BHATTACHARYA Mrinnanda (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BELL Lillie (Clausen), MIHAILOVIC Milica (Karagöz), GUYNES Keroshini (Jachowicz)Date: 2025-08-18, Time: 12:30:00, Speaker: BELL Lillie (Clausen)MIHAILOVIC Milica (Karagöz)GUYNES Keroshini (Jachowicz), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BOHL VIALLEFONT Gregoire (Nordborg), MARCHIORI Elisa (Van der Veeken), JAHNEL Stefan (Mendjan)Date: 2025-08-25, Time: 12:30:00, Speaker: BOHL VIALLEFONT Gregoire (Nordborg)MARCHIORI Elisa (Van der Veeken)JAHNEL Stefan (Mendjan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KIRCHGATTERER Paul (Gaidt), ACHLEITNER Sonja (Martens), KAYA Oguzhan (Knoblich)Date: 2025-09-01, Time: 12:30:00, Speaker: KIRCHGATTERER Paul (Gaidt)ACHLEITNER Sonja (Martens)KAYA Oguzhan (Knoblich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HUTH Michelle (Leeb), RADHAKRISHNA PILLAI Balashankar (Brennecke), REN Kaike (Otsuka)Date: 2025-09-08, Time: 12:30:00, Speaker: HUTH Michelle (Leeb)RADHAKRISHNA PILLAI Balashankar (Brennecke)REN Kaike (Otsuka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GONZALEZ ALVARADO Maria Nazareth (Grade), KASHKO Nataliia (Matos), OBERHUEMER Michael (Leeb)Date: 2025-09-15, Time: 12:30:00, Speaker: GONZALEZ ALVARADO Maria Nazareth (Grade)KASHKO Nataliia (Matos)OBERHUEMER Michael (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joao Matos, Peter Schlögelhofer Katja WassmannDate: 2025-09-18, Time: 11:00:00, Speaker: Katja Wassmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Institute Jacques Monod, Host: Joao Matos, Peter Schlögelhofer
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KONSTANTINOU Andri (Obenauf), HARTMANN Felix (Matos), JENTOFT Ida (Pauli)Date: 2025-09-22, Time: 12:30:00, Speaker: KONSTANTINOU Andri (Obenauf)HARTMANN Felix (Matos)JENTOFT Ida (Pauli), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Alex Stark Fabian TheisDate: 2025-09-25, Time: 11:00:00, Speaker: Fabian Theis, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Computational Health Center, Helmholtz Munich, Host: Alex Stark
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PAVLOVA Anzhela (Matos), SHARMA Sanskriti (Ellis), VETRANO Pamela (Ramundo)Date: 2025-09-29, Time: 12:30:00, Speaker: PAVLOVA Anzhela (Matos)SHARMA Sanskriti (Ellis)VETRANO Pamela (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WIGHARD Sara Sylvia (Burga), PRLESI Ines (Gerlich), BECHT Nanette (Gaidt)Date: 2025-10-06, Time: 12:30:00, Speaker: WIGHARD Sara Sylvia (Burga)PRLESI Ines (Gerlich)BECHT Nanette (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Elly Tanaka Alexander van OudenaardenDate: 2025-10-09, Time: 11:00:00, Speaker: Alexander van Oudenaarden, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Elly Tanaka
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PIECH Lucas (Leonard), NABIH MOSTAFA Amena (Pauli), GREMMELMAIER Constanze (Plaschka)Date: 2025-10-13, Time: 12:30:00, Speaker: PIECH Lucas (Leonard)NABIH MOSTAFA Amena (Pauli)GREMMELMAIER Constanze (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Andrea Pauli Anne BrunetDate: 2025-10-16, Time: 11:00:00, Speaker: Anne Brunet, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Stanford University, Host: Andrea Pauli
Monday Seminar (Internal)
12:30 IMP Lecture Hall None KYPRIANOU Christos (Rivron), MOYSIADOU Sofia (Obenauf), GALLAGE CHANUKA POSHITHA Fernando (Zimmer)Date: 2025-10-20, Time: 12:30:00, Speaker: KYPRIANOU Christos (Rivron)MOYSIADOU Sofia (Obenauf)GALLAGE CHANUKA POSHITHA Fernando (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz, Martin Leeb Aydan Bulut-KarsliogluDate: 2025-10-23, Time: 11:00:00, Speaker: Aydan Bulut-Karslioglu, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MPI Berlin, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
12:30 IMP Lecture Hall None IAROVENKO Svetlana (Brennecke), HIDAKA Takuya (Gerlich)Date: 2025-10-27, Time: 12:30:00, Speaker: IAROVENKO Svetlana (Brennecke)HIDAKA Takuya (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall David Haselbach Kresten Lindorff-LarssenDate: 2025-10-30, Time: 11:00:00, Speaker: Kresten Lindorff-Larssen, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: David Haselbach
Monday Seminar (Internal)
12:30 IMP Lecture Hall None DIAS Ana Beatriz (Slade), VALERI Erika (Gaidt), CHATZIANGELOU Myrto (Stark)Date: 2025-11-03, Time: 12:30:00, Speaker: DIAS Ana Beatriz (Slade)VALERI Erika (Gaidt)CHATZIANGELOU Myrto (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None FRASZ Lisa-Maria (Obenauf), MYLARSHCHIKOV Dmitry (Gerlich), SAHA Sayantan (Huis)Date: 2025-11-10, Time: 12:30:00, Speaker: FRASZ Lisa-Maria (Obenauf)MYLARSHCHIKOV Dmitry (Gerlich)SAHA Sayantan (Huis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
11:00 IMBA/GMI Lecture Hall Joanna Jachowicz, Martin Leeb Jamie HackettDate: 2025-11-13, Time: 11:00:00, Speaker: Jamie Hackett, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: EMBL Rome, Host: Joanna Jachowicz, Martin Leeb
Monday Seminar (Internal)
12:30 IMP Lecture Hall None PITASI Mattia (Leeb), FORBES Rebecca (Görke), MATURI Samuele (Grade)Date: 2025-11-17, Time: 12:30:00, Speaker: PITASI Mattia (Leeb)FORBES Rebecca (Görke)MATURI Samuele (Grade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
To be annouced
11:00 IMBA/GMI Lecture Hall Marco Hein Noam Stern-GinossarDate: 2025-11-20, Time: 11:00:00, Speaker: Noam Stern-Ginossar, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute of Science, Host: Marco Hein
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HEINZL Monika (Stark), MARTZIOS Panagiotis (Huis), BASTOS VENTURA Guilherme (Pinheiro)Date: 2025-11-24, Time: 12:30:00, Speaker: HEINZL Monika (Stark)MARTZIOS Panagiotis (Huis)BASTOS VENTURA Guilherme (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None JONASSON Mattias (Bücker), KNAUDT Hannah (Haselbach)Date: 2025-12-01, Time: 12:30:00, Speaker: JONASSON Mattias (Bücker)KNAUDT Hannah (Haselbach), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BERKUN Kathleen (Hallacli), , GRAF Max (Plaschka)Date: 2025-12-15, Time: 12:30:00, Speaker: BERKUN Kathleen (Hallacli)GRAF Max (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None BOHAUMILITZKY Lena (Pinheiro), SPEICHERT Katarzyna (Martens), NG Hing Pan (Ma)Date: 2026-01-12, Time: 12:30:00, Speaker: BOHAUMILITZKY Lena (Pinheiro)SPEICHERT Katarzyna (Martens)NG Hing Pan (Ma), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None FARAWAY Rupert (Plaschka), ETHIER Elizabeth (Hallacli), RAINA Shiviya (Dammermann)Date: 2026-01-19, Time: 12:30:00, Speaker: FARAWAY Rupert (Plaschka)ETHIER Elizabeth (Hallacli)RAINA Shiviya (Dammermann), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None WULF Paul Oliver (Tessmar), MISHRA Sachin (Stark), OGZUC Olivia (Querques)Date: 2026-01-26, Time: 12:30:00, Speaker: WULF Paul Oliver (Tessmar)MISHRA Sachin (Stark)OGZUC Olivia (Querques), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None COSTANTINI Elena (Tanaka), VIOHL Niklas (Köhler), LEON-RUIZ Jesus (Dolan)Date: 2026-02-02, Time: 12:30:00, Speaker: COSTANTINI Elena (Tanaka)VIOHL Niklas (Köhler)LEON-RUIZ Jesus (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None MIOCIC-STOSIC Fran (Zagrovic), BELL Caelan (Gerlich), KLEINWAECHTER Ava (Slade)Date: 2026-02-09, Time: 12:30:00, Speaker: MIOCIC-STOSIC Fran (Zagrovic)BELL Caelan (Gerlich)KLEINWAECHTER Ava (Slade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None HOFMANN Maura (Van der Veeken), SEN Zeynep Begüm (Ma), ZEN PETISCO FIORE Ana Paula (Urban)Date: 2026-02-16, Time: 12:30:00, Speaker: HOFMANN Maura (Van der Veeken)SEN Zeynep Begüm (Ma)ZEN PETISCO FIORE Ana Paula (Urban), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None JANKOWSKA Julia (Ameres), DOCAVO GARCIA Antonio (Jachowicz), HAONAN Bao (Dolan)Date: 2026-02-23, Time: 12:30:00, Speaker: JANKOWSKA Julia (Ameres)DOCAVO GARCIA Antonio (Jachowicz)HAONAN Bao (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None RUSSETT Colleen (Berger), ZEILER Christine (Kovarik), HOLLAUS David (Gaidt)Date: 2026-03-02, Time: 12:30:00, Speaker: RUSSETT Colleen (Berger)ZEILER Christine (Kovarik)HOLLAUS David (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
12:30 IMP Lecture Hall None GUZMAN PEREZ Sebastian (Martinez), ROFFAY Chloe (Pinheiro), BHARDWAJ Vishakha (Schlögelhofer)Date: 2026-03-09, Time: 12:30:00, Speaker: GUZMAN PEREZ Sebastian (Martinez)ROFFAY Chloe (Pinheiro)BHARDWAJ Vishakha (Schlögelhofer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
