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Chromosomes are the biologically relevant form of organization of the genome in all known forms of life. Eukaryotes, but not prokaryotes, possess basic proteins, which organize DNA as chromatin, possibly to suppress transcriptional noise and chemical instability and to foster phase separation. Eukaryotes also developed sustainable sexual reproduction, involving regular fusion and fission of genomes, the latter known as meiosis, which converts a diploid precursor cell into four haploid products. In meiosis, homologs from each parent must be identified, linked by chiasmata and finally be transported to opposite meiotic products. We currently address the mechanism of identification, initiated by Spo11 mediated double-strand break formation, as well, as homology search and repair. In most organisms a subset of DSBs is turned into crossing over, the basis of the physical linkage between the homologues. Taken together, we study chromosome segregation mediated by meiotic recombination.
Using budding yeast as model organism, we first established chromosome preparations suitable for immunofluorescence (IF) of yeast chromosomes. Fig. 1 shows spreads representing 10 consecutive stages from premeiotic S-phase until the end of meiosis, 4 haploid nuclei. DNA (blue, DAPI) is decorated with red foci (Smc6 – mediator of genome stability and Holliday-junction resolution) and green lines (Zip1 – mediator of synapsis). For molecular resolution, we perform ChIP-Seq, which yields genome-wide maps of proteins on DNA. For Spo11, we have developed a novel technology, Protec-Seq, which returns meiotic DNA lesions with single nucleotide precision. With this technique, we discovered that dsDNA pieces are excised from chromosomes. Fig. 2 shows such mapped, excised DNA pieces in the form of colored half circles. Of course, we also use the strength of our model system, genetics, to perform forward and reverse genetic screens, and use the ease of genetic manipulations including CRISPR.
1987 Franz Klein received a PhD in yeast genetics with U. Wintersberger (I. Krebsforschung), and moved to D. Schweizer, I. Botanik.
1991 post doc with Breck Byers, U. of Washington.
2000 habilitation in Genetics following the discovery of meiotic cohesin Rec8 and its central role in meiosis.
2008 Coordinator of SFB “Chromosome Dynamics”
2011 full Univ Prof, 2015 Chair of Chromosome Biology.
Our discovery of COM1/Sae2/CtIP and the defect in DSB repair and synapsis in com1 mutants shows that fully formed, tripartite SC depends on DSB repair (TEM of silver stained yeast spreads). Subsequently orthologs in plants and animals with roles in meiosis and genome stability were discovered. We also found that MRE11 is essential for meiotic DSB repair (Nairz and Klein, 1997; Prinz at all, 1997).
In collaboration with Kim Nasmyth, we discovered scRec8 and demonstrated its fundamental functions. Importantly, the pattern of its localization led us to propose that deposition of cohesin in S-phase is followed by removal of cohesin on chromosome arms to trigger anaphase I (Fig.3 C, D) and removal of cohesin at kinetochores to trigger anaphase II (Fig.3 E, Klein et al., 1999). Now in textbooks.
High resolution mapping of the break machinery revealed its presence at the sites of cohesin, that is, at the chromosome axis (Fig. 4 blue,red symbol). Because DNA breaks occur away from the axis, these sequences must transiently interact with the break machinery for cleavage (Fig.4 red star, Panizza, 2011). DSB formation during axis tethering is likely conserved in all Eukaryotes.
The Smc5/6/Mms21 complex is related to cohesin. We demonstrated that Smc5/6 has 2 independent roles: to prevent and to resolve JMs (Joint Molecules, double Holliday Junctions). Fig.5 shows lethal accumulation of unresolved JMs during synchronous meiosis in smc6-ts (Xaver et al., 2013). Smc5/6 may detect branched DNA molecules to inform helicases (Blooms) or resolvases (Mus81) about their geometry.
We knew for 35 years that meiotic recombination is initiated by chromosome breaks, but only now we discovered that in this process often whole chromosome pieces are chopped out. We developed a novel method to map those fragments, which resulted in unprecedented, single nucleotide accuracy and allowed new key observations, such as to identify a DNA bending motive at preferred cleavage sites.
The mechanism could lead to enhanced chromosome evolution, as well as to pathogenic mutations, if repair fails.
Spo11 generates gaps through concerted cuts at sites of topological stress.
Prieler, Silvia; Chen, Doris; Huang, Lingzhi; Mayrhofer, Elisa; Zsótér, Soma; Vesely, Magdalena; Mbogning, Jean; Klein, Franz
Transcription dynamically patterns the meiotic chromosome-axis interface.
Sun, Xiaoji; Huang, Lingzhi; Markowitz, Tovah E; Blitzblau, Hannah G; Chen, Doris; Klein, Franz; Hochwagen, Andreas
Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis.
Martin Xaver, Lingzhi Huang, Doris Chen and Franz Klein
Spo11-accessory proteins link double-strand break sites to the chromosome axis in early meiotic recombination.
Panizza, Silvia; Mendoza, Marco A; Berlinger, Marc; Huang, Lingzhi; Nicolas, Alain; Shirahige, Katsuhiko; Klein, Franz
Franz Klein is speaker of the Special Research Area (SFB) "Chromosome Dynamics - Unraveling the function of chromosomal domains" funded by the Austrian Science Fund FWF. SFB's are peer-reviewed, highly interactive research networks, established to foster long-term, interdisciplinary co-operation of local research groups working on the frontiers of their thematic areas.
The Group Klein participates in in the special Doctoral Program 'Chromosome Dynamics' reviewed and funded by the Austrian Research Fund FWF.
Shaping morphogen gradients: from molecules to tissues and back
Date: 2024-05-17, Time: 09:00:00, Speaker: Zena Hadjivasiliou, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: The Francis Crick Institute, Host: Diana Pinheiro
Title to be announced
Date: 2024-05-23, Time: 14:00:00, Speaker: Ben Engel, Location: VBC5 Lecture Hall A+B/Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Biozentrum Basel, Host: Irma Querques
Studying stressed cells by in situ structural biology
Date: 2024-05-23, Time: 11:00:00, Speaker: Simone Mattei, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: EMBL, Host: Yasin Dagdas
The role of non-canonical double strand break repair pathways in genome stability and diversity
Date: 2024-05-23, Time: 09:30:00, Speaker: Alessandra Brambati, Location: IMBA Lecture Hall, Type: IMP GL Interview Seminar, Institute: Sloan Kettering Institute, New York, Host: TBC
Vienna BioCenter Industry Insights event, hosting Merck
Date: 2024-05-27, Time: 17:00:00, Speaker: Dr Shashi Jasty and Dr Stephanie Linker, Location: IMP Lecture Hall, Type: VBC Industry Insights QandA and Networking, Institute: Merck, Host: VBC Industry Insights team
Building and regenerating the vertebrate retina
Date: 2024-05-27, Time: 15:00:00, Speaker: Seth Blackshaw, Location: IMP Lecture Hall, Type: Impromptu Seminar, Institute: Johns Hopkins University School of Medicine, Host: Elly Tanaka
Monday Seminar (Internal)
Date: 2024-05-27, Time: 12:30:00, Speaker: VELETI Lalitha (Pauli)andlt;brandgt;ENGL Magdalena (Slade)andlt;brandgt;NAAS Julia (Van Haeseler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Date: 2024-05-28, Time: 13:15:00, Speaker: Isabella Moll, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Max Perutz Labs, Uni Wien, Host: Silvia Bulgheresi
Building the C. elegans synaptonemal complex
Date: 2024-05-28, Time: 11:30:00, Speaker: Yumi Kim, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: Johns Hopkins University, Baltimore, Host: Verena Jantsch
Arbuscular mycorrhiza development and function
Date: 2024-05-29, Time: 11:00:00, Speaker: Caroline Gutjahr, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MPI Potsdam, Host: Liam Dolan
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
Date: 2024-06-03, Time: 13:30:00, Speaker: Todd Oakley, Location: UBB - Lecture Hall 2, Type: Max Perutz Labs Impromptu Seminar, Institute: UCSB, Department of Ecology, Evolution and Marine Biology, Host: Kristin Tessmar-Raible
Monday Seminar (Internal)
Date: 2024-06-03, Time: 12:30:00, Speaker: FIESELER Charlie (Zimmer)andlt;brandgt;GRUNDMANN Lorenz (Haselbach)andlt;brandgt;KLEINWAECHTER Ava (Slade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
Date: 2024-06-04, Time: 13:15:00, Speaker: Daniel Stadtmauer, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: KLI/UniWien, Host: Mihaela Pavlicev
Max Perutz PhD Fellowship Mini-Symposium
The Max Perutz PhD Fellowship was established in 2021 to reward outstanding PhD students. Four internationally accomplished researchers from the EMBO Young Investigator Program will form this year’s selection committee. On this occasion they will give talks on their exciting research.
The unanticipated roles of PICIs and phages in bacterial evolution
Date: 2024-06-06, Time: 12:00:00, Speaker: Jose R. Penades, Location: UBB - Lecture Hall 2, Type: CMESS Lecture Series, Institute: Imperial College London, Host: Martin Polz
Chemical targeting of subcellular protein localization
Date: 2024-06-06, Time: 11:00:00, Speaker: Stefan Kubicek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: CeMM, Host: Johannes Zuber
From animacules to plants: Insights into the evolution of eukaryotic sexuality from Volvox and volvocine algae
Date: 2024-06-07, Time: 11:30:00, Speaker: James Umen, Location: GMI Orange Seminar Room, Type: GMI Seminar, Institute: Donald Danforth Plant Science Center, Host: Silvia Ramundo
Monday Seminar (Internal)
Date: 2024-06-10, Time: 12:30:00, Speaker: RÖTZER Johannes (Dolan)andlt;brandgt;MIOCIC-STOSIC Fran (Zagrovic)andlt;brandgt;WOLFF Uyen Le Phoung (Jantsch), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Origin and diversification of gut-derived organs in chordates
Date: 2024-06-11, Time: 13:15:00, Speaker: Arun Chavan, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Yale Medical School, Host: Günter Wagner
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Date: 2024-06-11, Time: 11:00:00, Speaker: David Pellman, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Dana Farber Cancer Institute, Host: Shotaru Otsuka
Connections between carbon and nitrogen cycling in the ocean
Date: 2024-06-13, Time: 12:00:00, Speaker: Barbara Bayer, Location: UBB - Lecture Hall 2, Type: CMESS Lecture Series, Institute: CeMESS, University of Vienna, Host: Michael Wagner
Monday Seminar (Internal)
Date: 2024-06-17, Time: 12:30:00, Speaker: PUSHPA BOSE Greeshma (Urban)andlt;brandgt;FARAWAY Rupert (Plaschka)andlt;brandgt;RAINA Shiviya (Dammermann), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
Date: 2024-06-18, Time: 11:30:00, Speaker: Pascal Bernard, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: ENS de Lyon, Host: Franz Klein
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
Date: 2024-06-19, Time: 10:30:00, Speaker: Liron Bar-Peled, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: Harvard Medical School, Host: Johannes Zuber
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
Date: 2024-06-20, Time: 12:00:00, Speaker: Thorsten Reemtsma, Location: UBB - Lecture Hall 2, Type: CMESS Lecture Series, Institute: Helmholtz-Centre for Environmental Research, Host: Thilo Hofmann
What Asgard Archaea can tell us about the origin of Eukaryotes
Date: 2024-06-20, Time: 11:00:00, Speaker: Christa Schleper, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Vienna, Host: Clemens Plaschka
Monday Seminar (Internal)
Date: 2024-06-24, Time: 12:30:00, Speaker: BELL Caelan (Gerlich)andlt;brandgt;PABST Gabriel (Zuber)andlt;brandgt;BOHAUMILITZKY Lena (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
FENS 2024 Satellite event: Home cage behavior monitoring at the interface of animal welfare and neuroscience
Date: 2024-06-24, Time: 09:00:00, Speaker: , Location: IMP Seminar Room 1.014/16, Type: Symposium, Institute: None, Host: Daniela Pollak
Title to be announced
Date: 2024-06-25, Time: 11:30:00, Speaker: Attila Toth, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: TU Dresden, Host: Franz Klein
A mechanism for protein complex regulation at the mitochondrial surface
Date: 2024-06-27, Time: 11:00:00, Speaker: Susan Shao, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Harvard Medical School, Host: Andrea Pauli
Monday Seminar (Internal)
Date: 2024-07-01, Time: 12:30:00, Speaker: RUSSETT Colleen (Berger)andlt;brandgt;NAJM Ramsey (Knoblich)andlt;brandgt;HOLLAUS David (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-07-08, Time: 12:30:00, Speaker: JANKOWSKA Julia (Ameres)andlt;brandgt;PAPAREDDY Ranjith (Dagdas)andlt;brandgt;ROFFAY Chloe (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-07-15, Time: 12:30:00, Speaker: ZEILER Christina (Kovarik)andlt;brandgt;BHARDWAJ Vishakha (Schlögelhofer)andlt;brandgt;DIEZMA Laura (Nordborg/Mari-Ordonez), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-07-18, Time: 11:00:00, Speaker: Wanda Kukulski, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Bern, Host: Elif Karagöz
Monday Seminar (Internal)
Date: 2024-07-22, Time: 12:30:00, Speaker: GUZMAN PEREZ Sebastian (Martinez)andlt;brandgt;LITTLEBOY Jamie (Knoblich)andlt;brandgt;ZMAJKOVIC Jakub (Zuber), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-07-29, Time: 12:30:00, Speaker: MAURER Eric (Peters)andlt;brandgt;DOCAVO GARCIA Antonio (Jachowicz)andlt;brandgt;BABADEI Olga (Decker), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-08-05, Time: 12:30:00, Speaker: DEL CHIARO Alessia (Dagdas)andlt;brandgt;ANTONIOLI Sumire (Leonard)andlt;brandgt;SHETTY Kavya (Hein), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-08-12, Time: 12:30:00, Speaker: HUETTER Christiane (Menche)andlt;brandgt;KRACHT Laura (Knoblich)andlt;brandgt;SANDRU Ana Maria (Baccarini), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-08-19, Time: 12:30:00, Speaker: BENEDUM Johannes (Slade)andlt;brandgt;KALIS Robert (Zuber)andlt;brandgt;PATEL Rajvi (Matos), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-08-26, Time: 12:30:00, Speaker: PROTSENKO Liudmila (Brennecke)andlt;brandgt;SILVA Raquel (Foisner)andlt;brandgt;BASSAT Elad (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-09-02, Time: 12:30:00, Speaker: SCHAAR Benjamin (Zimmer)andlt;brandgt;IGOLKINA Anna (Nordborg)andlt;brandgt;JANSEN Ralf (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Striking physiology and cell biology of (marine) environmental microorganisms
Date: 2024-09-03, Time: 11:30:00, Speaker: Ralf Rabus, Location: Max Perutz Labs SR 1 (6th floor), Type: New Developments in Chromosome Biology, Institute: ICBM, Carl von Ossietzky Universität Oldenburg, Host: Kristin Tessmar-Raible
Title to be announced
Date: 2024-09-05, Time: 11:00:00, Speaker: Alexander Van Oudenaarden, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Daniel Gerlich
Monday Seminar (Internal)
Date: 2024-09-09, Time: 12:30:00, Speaker: STUART Hannah (Tanaka)andlt;brandgt;ROVERA Emanuele (Zuber)andlt;brandgt;KLOSS Linda (Technau), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Mechanisms controlling maintenance of cohesin dependent loops
Date: 2024-09-10, Time: 11:30:00, Speaker: Frederic Beckouet, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: Toulouse Centre de Biologie Intégrative, Host: Franz Klein
Title to be announced
Date: 2024-09-12, Time: 11:00:00, Speaker: Elcin Ünal, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: UC Berkeley, Host: Silvia Ramundo, Fred Berger
Monday Seminar (Internal)
Date: 2024-09-16, Time: 12:30:00, Speaker: WUN Cheuk Ling (Ramundo)andlt;brandgt;MÜLLER Marlene (Rivron)andlt;brandgt;RAUSCHMEIER Rene (Van der Veeken), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-09-19, Time: 11:00:00, Speaker: Noam Stern-Ginossar, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute of Science, Host: Marco Hein
Monday Seminar (Internal)
Date: 2024-09-23, Time: 12:30:00, Speaker: ESTIVILL I CAPARROS Guillem (Obenauf)andlt;brandgt;VOJTEK Matus (Stark)andlt;brandgt;DA COSTA Barbara (Berger), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-09-26, Time: 11:00:00, Speaker: Maria Mota, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lisbon, Host: Joao Matos
Title to be announced
Date: 2024-09-27, Time: 11:00:00, Speaker: Deborah Bourcand#x27;his, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: Institut Curie, Host: Julius Brennecke
Monday Seminar (Internal)
Date: 2024-09-30, Time: 12:30:00, Speaker: JÄGER Christina (Van der Veeken)andlt;brandgt;SHUKLA Vikas (Berger)andlt;brandgt;RODRIGUEZ TERRONES Diego (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-10-07, Time: 12:30:00, Speaker: KANNO Tatsuo (Berger)andlt;brandgt;SCHIMMER Clara (Ellis)andlt;brandgt;DE SANTIS Martina (Rivron), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-10-10, Time: 11:00:00, Speaker: Cedric Blanpain, Location: , Type: , Institute: Universite Libres Bruxelles, Host: Stephanie Ellis
Monday Seminar (Internal)
Date: 2024-10-14, Time: 12:30:00, Speaker: GAO Peng (Dagdas)andlt;brandgt;RAFANEL Baptiste (Brennecke)andlt;brandgt;FRIDRICH Arie (Berger), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-10-17, Time: 11:00:00, Speaker: Ralf Jungmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: LMU, MPI, Host: Alex Stark, Francisco Balzarotti
Monday Seminar (Internal)
Date: 2024-10-21, Time: 12:30:00, Speaker: MILOJKOVIC Lidija (Urban)andlt;brandgt;SPENCER Victoria (Dolan)andlt;brandgt;AUGUSTO Pedro (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-10-24, Time: 11:00:00, Speaker: Andrea Ablasser, Location: IMP Lecture Hall, Type: VBC Regular Seminar, Institute: EPFL, Host: Moritz Gaidt
Monday Seminar (Internal)
Date: 2024-10-28, Time: 12:30:00, Speaker: GOMEZ SEGALAS Alba (Balzarotti)andlt;brandgt;KLEINFERCHER Sebastian (Stark)andlt;brandgt;PRADHAN Saurabh (Rivron), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-11-04, Time: 12:30:00, Speaker: SCHEPERS Sandra (Knoblich)andlt;brandgt;BUSETTO Virginia (Falk)andlt;brandgt;DMITRIEV Vladimir (Goloborodko), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
VBC PhD Symposium
Date: 2024-11-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2024-11-11, Time: 12:30:00, Speaker: GARCIA GALLARDO Maria (Bücker)andlt;brandgt;HARVEY Zachary (Berger)andlt;brandgt;SAKALLI Enes (Von Haeseler,Menche), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-14, Time: 11:00:00, Speaker: Benoit Bruneau, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Gladstone Institute of Cardiovascular Disease, UCSF, Host: Sasha Menjdan
Monday Seminar (Internal)
Date: 2024-11-18, Time: 12:30:00, Speaker: FESSELET Jeanne (Kovarik)andlt;brandgt;GIAGNISI Eleftheria (Zimmer)andlt;brandgt;SHEN Jingyi (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-18, Time: 11:00:00, Speaker: Lacramioara Bintu, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: Stanford University, Host: Alex Stark
Title to be announced
Date: 2024-11-21, Time: 11:00:00, Speaker: Martin Jinek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Zurich, Host: Irma Querques
Monday Seminar (Internal)
Date: 2024-11-25, Time: 12:30:00, Speaker: BOREIKAITE Vytaute (Plaschka)andlt;brandgt;SRINIVASAN Navaneeth (Peters)andlt;brandgt;DODOMANI Ananya (Campbell), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-28, Time: 18:00:00, Speaker: David Baker, Location: Zoom, Type: VBC Regular Seminar via Zoom, Institute: UW Dept. of Biochemistry, Host: Alwin Köhler
Monday Seminar (Internal)
Date: 2024-12-02, Time: 12:30:00, Speaker: SOMMER Theresa (Rivron)andlt;brandgt;GORBENKOVA Anastasiia (Leonard)andlt;brandgt;MAIR Zahar (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-12-05, Time: 11:00:00, Speaker: Ian Hickson, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Joao Matos
Monday Seminar (Internal)
Date: 2024-12-09, Time: 12:30:00, Speaker: BREHM Martin (Falk)andlt;brandgt;PLATZER Sebastian (Hein)andlt;brandgt;HANDLER Dominik (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-12-12, Time: 11:00:00, Speaker: Stephen West, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: The Francis Crick Institute, Host: Joao Matos
Monday Seminar (Internal)
Date: 2024-12-16, Time: 12:30:00, Speaker: DAHAN Tal (Nordborg)andlt;brandgt;CHUGUNOVA Anastasia (Pauli)andlt;brandgt;VON WIREN Julius (Kovarik), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-01-13, Time: 12:30:00, Speaker: KRASNOVID Filipp (Mari-Ordonez)andlt;brandgt;ROTHE Patricia (Plaschka)andlt;brandgt;KROGULL Daniel (Burga), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-01-20, Time: 12:30:00, Speaker: VICIC Ziga (Jachowicz)andlt;brandgt;GRÜNEWALD Jakob (Obenauf)andlt;brandgt;MANOLOVA Toni (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-01-27, Time: 12:30:00, Speaker: SCARAMUZZA Federico (Tessmar)andlt;brandgt; WALTER Mateusz (Querques)andlt;brandgt;WILLIAMS Thomas (Clausen), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-02-03, Time: 12:30:00, Speaker: CRUZ Joseph (Gerlich)andlt;brandgt;GHEORGHITA Andreea (Clausen)andlt;brandgt;GALUSKA Philipp (Djinovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-02-10, Time: 12:30:00, Speaker: GRIGOREVA Elizaveta (Nordborg)andlt;brandgt;KOHOUTKOVA Eliska (Clausen)andlt;brandgt;STEINACKER Thomas (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-02-17, Time: 12:30:00, Speaker: RAFFL Gerald (Ameres)andlt;brandgt;VULIN Milica (Obenauf)andlt;brandgt;FISCHER Andre (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-02-24, Time: 12:30:00, Speaker: BAYERL Jonas (Zuber)andlt;brandgt;ZABOLOCKI Michael (Knoblich)andlt;brandgt;EDER Stephanie (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-02-27, Time: 11:00:00, Speaker: Cedric Feschotte, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Cornell University, Host: Joanna Jachowicz
Monday Seminar (Internal)
Date: 2025-03-03, Time: 12:30:00, Speaker: KROETENHEERDT Eva (Leonard)andlt;brandgt;RÖHSNER Josef (Pauli)andlt;brandgt;RIABOV Daria (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-10, Time: 12:30:00, Speaker: CHO Chung Hyun (Berger)andlt;brandgt;SEIDL Carina (Tanaka)andlt;brandgt;MIGOTTI Mario (Konrat), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-17, Time: 12:30:00, Speaker: CHEN Shenzhi (Stark)andlt;brandgt;BINDL Michael (Leeb)andlt;brandgt;JÄGER Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-24, Time: 12:30:00, Speaker: MAYA Juan (Balzarotti)andlt;brandgt;DOSA Anna (Clausen)andlt;brandgt;KOBER Julia (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-31, Time: 12:30:00, Speaker: HOLZER Elisabeth (Martens)andlt;brandgt;THEMANN Jan (Knoblich)andlt;brandgt;GROSS Angelina (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-07, Time: 12:30:00, Speaker: GROH Roan (Dagdas)andlt;brandgt;CHAO Victor (Huis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-14, Time: 12:30:00, Speaker: OKUN Anastasia (Karagöz)andlt;brandgt;COLLISON Robert (Ramundo)andlt;brandgt;WELZL Paul (Balzarotti/Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-28, Time: 12:30:00, Speaker: SUWITA Johannes (Pauli)andlt;brandgt;GRABARCZYK Daniel (Clausen)andlt;brandgt;PANDA Aswini (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-05, Time: 12:30:00, Speaker: KIM Olena (Knoblich)andlt;brandgt;JOB Nikhil (Dolan)andlt;brandgt;ADELMANN Leonie (Raible), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Microsymposium on Small RNA Biology
Date: 2025-05-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2025-05-12, Time: 12:30:00, Speaker: SCIBISZ Grzegorz (Karagöz)andlt;brandgt;VAN GENDEREN Emiel (Rivron)andlt;brandgt;BOZKURT Miray (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-19, Time: 12:30:00, Speaker: POTTENDORFER Elisabeth (Obenauf)andlt;brandgt;WALLNER Eva-Sophie (Dolan)andlt;brandgt;BECKER Moritz (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-26, Time: 12:30:00, Speaker: DIMITROVA Polina (Van der Veeken)andlt;brandgt;STRAVS Ana (Knoblich)andlt;brandgt;SCHÖNLEIN Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-02, Time: 12:30:00, Speaker: SABATH Kevin (Plaschka/Stark)andlt;brandgt;MANCHENO JUNCOSA Estela (Mendjan)andlt;brandgt;HORENKAMP Simone (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-16, Time: 12:30:00, Speaker: BERGER Sonja (Goloborodko)andlt;brandgt;KOWALD Saskia (Gaidt)andlt;brandgt;KAPRAL Thomas (Zagrovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-23, Time: 12:30:00, Speaker: BUCHERON Chloe (Menche)andlt;brandgt;KRUMWIEDE Luisa (Gaidt)andlt;brandgt;PACHANO Tomas (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-30, Time: 12:30:00, Speaker: SCHINDLER Lukas (Schlögelhofer)andlt;brandgt;MANDLBURGER Nikolaus (Stark)andlt;brandgt;OTTO Magdalena (Leonard), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-07, Time: 12:30:00, Speaker: TRUS Palina (Peters)andlt;brandgt;KOBAKHIDZE George (Dong)andlt;brandgt;KONGSTED Thea (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-14, Time: 12:30:00, Speaker: RUSCH Emma (Golobordko)andlt;brandgt;VELIKOV Daniel (Matos), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-21, Time: 12:30:00, Speaker: ANGELOPOULOU Eleni (Ellis)andlt;brandgt;SCHAFFER Petra (Grade)andlt;brandgt;RAMIREZ America (Köhler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-28, Time: 12:30:00, Speaker: DIMITRIADI Anna (Mendjan)andlt;brandgt;LEITNER Moritz (Martinez)andlt;brandgt;RAUH Felix (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-04, Time: 12:30:00, Speaker: LI Wenxin (Zimmer)andlt;brandgt;FISCHER Felix (Zagrovic)andlt;brandgt;ABESAMIS Kim Ivan (Dong), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-11, Time: 12:30:00, Speaker: KLEIFELD Justus (Urban)andlt;brandgt;MCATEER Tara (Pinheiro)andlt;brandgt;BHATTACHARYA Mrinnanda (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-18, Time: 12:30:00, Speaker: BELL Lillie (Clausen)andlt;brandgt;MIHAILOVIC Milica (Karagöz)andlt;brandgt;GUYNES Keroshini (Jachowicz), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-25, Time: 12:30:00, Speaker: BOHL VIALLEFONT Gregoire (Nordborg)andlt;brandgt;MARCHIORI Elisa (Van der Veeken)andlt;brandgt;JAHNEL Stefan (Mendjan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-01, Time: 12:30:00, Speaker: KIRCHGATTERER Paul (Gaidt)andlt;brandgt;ACHLEITNER Sonja (Martens)andlt;brandgt;KAYA Oguzhan (Knoblich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-08, Time: 12:30:00, Speaker: HUTH Michelle (Leeb)andlt;brandgt;RADHAKRISHNA PILLAI Balashankar (Brennecke)andlt;brandgt;REN Kaike (Otsuka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-15, Time: 12:30:00, Speaker: GONZALEZ ALVARADO Maria Nazareth (Grade)andlt;brandgt;KASHKO Nataliia (Matos)andlt;brandgt;OBERHUEMER Michael (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None