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Cells survive, proliferate, and differentiate by interpreting the signals from the environment and translating them into the right output. If signaling goes awry, even in a few cells, the whole organism is at risk. We focus on signaling by the RAF/MEK/ERK pathway, an evolutionarily conserved kinase module which relays signals through consecutive phosphorylation of proteins arranged in three tiers. Constitutive activation of the pathway is a key event in several human malignancies and developmental disorders. Thus, proteins in this pathway are attractive therapeutic targets.
Strikingly, the pathway increases in complexity with evolution - from one paralog in simple organisms to three RAF, two MEK and two ERK paralogs in vertebrates. We investigate the essential roles of RAF and MEK paralogs and have discovered that they are indispensable for pathway cross‐talk, with functional consequences for homeostasis at the molecular, cellular, and organismal level.
The lab continues to focus on deciphering signaling pathways in the context of the whole organism, using a blend of genetics, molecular biology, biochemistry and cell biology. Since the essential functions of RAF and MEK paralogs are based primarily on their ability to undergo protein‐protein interactions with components of other signaling pathways, we are currently using an array of proximity labeling techniques coupled with mass spectrometry to understand the spatiotemporal context in which these complexes operate. To investigate the functional consequences of pathway perturbation, we rely mainly on primary cells and deploy single cell analysis of signaling pathways combined with single cell RNA‐seq to understand how RAF and MEK paralogs control cell fate decision.
Manuela is passionate about educating the next generation of scientists. She is the Director of the Vienna BioCenter PhD Program, a graduate school of the University of Vienna and Medical University of Vienna (link to the program website) and coordinates the FWF-funded PhD track “Signaling Mechanisms In Cellular Homeostasis”.
Hematopoietic stem cells (HSC) generate all cells in the blood, and are thus essential for our survival. HSC are rapidly activated when new blood is needed, but must go back to a dormant state lest the HSC compartment is exhausted. The fine balance between activation and dormancy is maintained by a negative feedback mechanism emanating from activated ERK and terminating ERK and AKT signaling.
The MEK paralog MEK1 dims signaling through the prosurvival PI3K/AKT pathway. Once modified by its substrate activated ERK, MEK1 binds to the lipid phosphatase PTEN and promotes its translocation to the plasma membrane. Here, PTEN breaks down the lipid second messenger PIP3, stopping AKT signaling. Thus, MEK1 balances signaling through two cascades that regulate cell proliferation and survival.
Activation of the RAF paralog RAF1 by growth factors and oncogenes generates distinct phosphorylated species which interact with the paralog BRAF, or with the cytoskeleton-based ROKα kinase. The BRAF complex is formed first and regulates ERK activation and proliferation, the ROKα complex regulates migration. RAF1 can be viewed as a moonlighting protein evolved to integrate distinct cell functions.
RAF1 ablation prevents the development and causes the regression of RAS-driven epidermal and lung tumors. In this system, RAS promotes complex formation between RAF1 and ROKα. RAF1 operates as an endogenous inhibitor of ROKα, which when unchecked induces exit from cell cycle and promotes keratinocyte differentiation.
RAF1 is required for RAS-driven lung and skin tumorigenesis. However in hepatocellular carcinoma (HCC) RAF1 puts the breaks on the proliferation of malignant hepatocytes, the actual tumor cells; therefore, and unexpectedly, RAF1 is a negative regulator of HCC. On the other hand, RAF1 is required in inflammatory cells of the tumor stroma to create an environment which stimulates HCC growth
29 March 2022
FEBS Journal Editor profile Manuela Baccarini
In this special interview series, the FEBS Journal profiles members of its editorial board: Read about Manuela's research, perspectives on the journal and future directions in her field.
Link: https://febs.onlinelibrary.wiley.com/share/TKQT7FK6FVRGMQIQCG5M?target=10.1111/febs.16423
17 February 2022
Interview: The social network of our cells
The group of Manuela Baccarini is investigating the way our cells communicate with each other. In this interview with "Rudolphina" by the University of Vienna, she talks about the 'signaling highway' in our bodies and about the way high throughput technologies revolutionised modern molecular cell biology research.
Link: https://rudolphina.univie.ac.at/cancer-research-when-communication-between-our-cells-fails
An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.
Baumgartner, Christian; Toifl, Stefanie; Farlik, Matthias; Halbritter, Florian; Scheicher, Ruth; Fischer, Irmgard; Sexl, Veronika; Bock, Christoph; Baccarini, Manuela
MEK1 Is Required for PTEN Membrane Recruitment, AKT Regulation, and the Maintenance of Peripheral Tolerance.
Zmajkovicova, Katarina,Jesenberger, Veronika, Catalanotti,Federica, Baumgartner, Christian, Reyes, Gloria und Manuela Baccarini
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Jeric, Ines; Maurer, Gabriele; Cavallo, Anna Lina; Raguz, Josipa; Desideri, Enrico; Tarkowski, Bartosz; Parrini, Matthias; Fischer, Irmgard; Zatloukal, Kurt; Baccarini, Manuela
Project title: “MEK1 complexes regulating the timing and strength of ERK and AKT signals" (P 26874)
Project title: “Role of MEK1 signaling in the regulation of hematopoiesis and leukemogenesis" (P 26303)
Project title: “Rolle der Raf Kinasen in Angiogenesis"
Project title: “The multi-scale dynamics of signal transduction: dissecting the MAPK pathway”
Manuela Baccarini co-ordinates the special Doctoral Program "Signaling Mechanisms in Cellular Homeostasis" reviewed and funded by the Austrian Science Fund FWF.
Shaping morphogen gradients: from molecules to tissues and back
Date: 2024-05-17, Time: 09:00:00, Speaker: Zena Hadjivasiliou, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: The Francis Crick Institute, Host: Diana Pinheiro
Title to be announced
Date: 2024-05-23, Time: 14:00:00, Speaker: Ben Engel, Location: VBC5 Lecture Hall A+B/Zoom, Type: Seminar Series on Modern Concepts in Structural Biology, Institute: Biozentrum Basel, Host: Irma Querques
Studying stressed cells by in situ structural biology
Date: 2024-05-23, Time: 11:00:00, Speaker: Simone Mattei, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: EMBL, Host: Yasin Dagdas
The role of non-canonical double strand break repair pathways in genome stability and diversity
Date: 2024-05-23, Time: 09:30:00, Speaker: Alessandra Brambati, Location: IMBA Lecture Hall, Type: IMP GL Interview Seminar, Institute: Sloan Kettering Institute, New York, Host: TBC
Vienna BioCenter Industry Insights event, hosting Merck
Date: 2024-05-27, Time: 17:00:00, Speaker: Dr Shashi Jasty and Dr Stephanie Linker, Location: IMP Lecture Hall, Type: VBC Industry Insights QandA and Networking, Institute: Merck, Host: VBC Industry Insights team
Building and regenerating the vertebrate retina
Date: 2024-05-27, Time: 15:00:00, Speaker: Seth Blackshaw, Location: IMP Lecture Hall, Type: Impromptu Seminar, Institute: Johns Hopkins University School of Medicine, Host: Elly Tanaka
Monday Seminar (Internal)
Date: 2024-05-27, Time: 12:30:00, Speaker: VELETI Lalitha (Pauli)andlt;brandgt;ENGL Magdalena (Slade)andlt;brandgt;NAAS Julia (Van Haeseler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Date: 2024-05-28, Time: 13:15:00, Speaker: Isabella Moll, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Max Perutz Labs, Uni Wien, Host: Silvia Bulgheresi
Building the C. elegans synaptonemal complex
Date: 2024-05-28, Time: 11:30:00, Speaker: Yumi Kim, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: Johns Hopkins University, Baltimore, Host: Verena Jantsch
Arbuscular mycorrhiza development and function
Date: 2024-05-29, Time: 11:00:00, Speaker: Caroline Gutjahr, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: MPI Potsdam, Host: Liam Dolan
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
Date: 2024-06-03, Time: 13:30:00, Speaker: Todd Oakley, Location: UBB - Lecture Hall 2, Type: Max Perutz Labs Impromptu Seminar, Institute: UCSB, Department of Ecology, Evolution and Marine Biology, Host: Kristin Tessmar-Raible
Monday Seminar (Internal)
Date: 2024-06-03, Time: 12:30:00, Speaker: FIESELER Charlie (Zimmer)andlt;brandgt;GRUNDMANN Lorenz (Haselbach)andlt;brandgt;KLEINWAECHTER Ava (Slade), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
Date: 2024-06-04, Time: 13:15:00, Speaker: Daniel Stadtmauer, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: KLI/UniWien, Host: Mihaela Pavlicev
Max Perutz PhD Fellowship Mini-Symposium
The Max Perutz PhD Fellowship was established in 2021 to reward outstanding PhD students. Four internationally accomplished researchers from the EMBO Young Investigator Program will form this year’s selection committee. On this occasion they will give talks on their exciting research.
The unanticipated roles of PICIs and phages in bacterial evolution
Date: 2024-06-06, Time: 12:00:00, Speaker: Jose R. Penades, Location: UBB - Lecture Hall 2, Type: CMESS Lecture Series, Institute: Imperial College London, Host: Martin Polz
Chemical targeting of subcellular protein localization
Date: 2024-06-06, Time: 11:00:00, Speaker: Stefan Kubicek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: CeMM, Host: Johannes Zuber
From animacules to plants: Insights into the evolution of eukaryotic sexuality from Volvox and volvocine algae
Date: 2024-06-07, Time: 11:30:00, Speaker: James Umen, Location: GMI Orange Seminar Room, Type: GMI Seminar, Institute: Donald Danforth Plant Science Center, Host: Silvia Ramundo
Monday Seminar (Internal)
Date: 2024-06-10, Time: 12:30:00, Speaker: RÖTZER Johannes (Dolan)andlt;brandgt;MIOCIC-STOSIC Fran (Zagrovic)andlt;brandgt;WOLFF Uyen Le Phoung (Jantsch), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Origin and diversification of gut-derived organs in chordates
Date: 2024-06-11, Time: 13:15:00, Speaker: Arun Chavan, Location: UBB - Lecture Hall 1, Type: Interaction and Evolution of Organisms Seminar Series, Institute: Yale Medical School, Host: Günter Wagner
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Date: 2024-06-11, Time: 11:00:00, Speaker: David Pellman, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Dana Farber Cancer Institute, Host: Shotaru Otsuka
Connections between carbon and nitrogen cycling in the ocean
Date: 2024-06-13, Time: 12:00:00, Speaker: Barbara Bayer, Location: UBB - Lecture Hall 2, Type: CMESS Lecture Series, Institute: CeMESS, University of Vienna, Host: Michael Wagner
Monday Seminar (Internal)
Date: 2024-06-17, Time: 12:30:00, Speaker: PUSHPA BOSE Greeshma (Urban)andlt;brandgt;FARAWAY Rupert (Plaschka)andlt;brandgt;RAINA Shiviya (Dammermann), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
Date: 2024-06-18, Time: 11:30:00, Speaker: Pascal Bernard, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: ENS de Lyon, Host: Franz Klein
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
Date: 2024-06-19, Time: 10:30:00, Speaker: Liron Bar-Peled, Location: GMI Orange Seminar Room, Type: Impromptu Seminar, Institute: Harvard Medical School, Host: Johannes Zuber
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
Date: 2024-06-20, Time: 12:00:00, Speaker: Thorsten Reemtsma, Location: UBB - Lecture Hall 2, Type: CMESS Lecture Series, Institute: Helmholtz-Centre for Environmental Research, Host: Thilo Hofmann
What Asgard Archaea can tell us about the origin of Eukaryotes
Date: 2024-06-20, Time: 11:00:00, Speaker: Christa Schleper, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Vienna, Host: Clemens Plaschka
Monday Seminar (Internal)
Date: 2024-06-24, Time: 12:30:00, Speaker: BELL Caelan (Gerlich)andlt;brandgt;PABST Gabriel (Zuber)andlt;brandgt;BOHAUMILITZKY Lena (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
FENS 2024 Satellite event: Home cage behavior monitoring at the interface of animal welfare and neuroscience
Date: 2024-06-24, Time: 09:00:00, Speaker: , Location: IMP Seminar Room 1.014/16, Type: Symposium, Institute: None, Host: Daniela Pollak
Title to be announced
Date: 2024-06-25, Time: 11:30:00, Speaker: Attila Toth, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: TU Dresden, Host: Franz Klein
A mechanism for protein complex regulation at the mitochondrial surface
Date: 2024-06-27, Time: 11:00:00, Speaker: Susan Shao, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Harvard Medical School, Host: Andrea Pauli
Monday Seminar (Internal)
Date: 2024-07-01, Time: 12:30:00, Speaker: RUSSETT Colleen (Berger)andlt;brandgt;NAJM Ramsey (Knoblich)andlt;brandgt;HOLLAUS David (Gaidt), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-07-08, Time: 12:30:00, Speaker: JANKOWSKA Julia (Ameres)andlt;brandgt;PAPAREDDY Ranjith (Dagdas)andlt;brandgt;ROFFAY Chloe (Pinheiro), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-07-15, Time: 12:30:00, Speaker: ZEILER Christina (Kovarik)andlt;brandgt;BHARDWAJ Vishakha (Schlögelhofer)andlt;brandgt;DIEZMA Laura (Nordborg/Mari-Ordonez), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-07-18, Time: 11:00:00, Speaker: Wanda Kukulski, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Bern, Host: Elif Karagöz
Monday Seminar (Internal)
Date: 2024-07-22, Time: 12:30:00, Speaker: GUZMAN PEREZ Sebastian (Martinez)andlt;brandgt;LITTLEBOY Jamie (Knoblich)andlt;brandgt;ZMAJKOVIC Jakub (Zuber), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-07-29, Time: 12:30:00, Speaker: MAURER Eric (Peters)andlt;brandgt;DOCAVO GARCIA Antonio (Jachowicz)andlt;brandgt;BABADEI Olga (Decker), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-08-05, Time: 12:30:00, Speaker: DEL CHIARO Alessia (Dagdas)andlt;brandgt;ANTONIOLI Sumire (Leonard)andlt;brandgt;SHETTY Kavya (Hein), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-08-12, Time: 12:30:00, Speaker: HUETTER Christiane (Menche)andlt;brandgt;KRACHT Laura (Knoblich)andlt;brandgt;SANDRU Ana Maria (Baccarini), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-08-19, Time: 12:30:00, Speaker: BENEDUM Johannes (Slade)andlt;brandgt;KALIS Robert (Zuber)andlt;brandgt;PATEL Rajvi (Matos), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-08-26, Time: 12:30:00, Speaker: PROTSENKO Liudmila (Brennecke)andlt;brandgt;SILVA Raquel (Foisner)andlt;brandgt;BASSAT Elad (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-09-02, Time: 12:30:00, Speaker: SCHAAR Benjamin (Zimmer)andlt;brandgt;IGOLKINA Anna (Nordborg)andlt;brandgt;JANSEN Ralf (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Striking physiology and cell biology of (marine) environmental microorganisms
Date: 2024-09-03, Time: 11:30:00, Speaker: Ralf Rabus, Location: Max Perutz Labs SR 1 (6th floor), Type: New Developments in Chromosome Biology, Institute: ICBM, Carl von Ossietzky Universität Oldenburg, Host: Kristin Tessmar-Raible
Title to be announced
Date: 2024-09-05, Time: 11:00:00, Speaker: Alexander Van Oudenaarden, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Hubrecht Institute, Host: Daniel Gerlich
Monday Seminar (Internal)
Date: 2024-09-09, Time: 12:30:00, Speaker: STUART Hannah (Tanaka)andlt;brandgt;ROVERA Emanuele (Zuber)andlt;brandgt;KLOSS Linda (Technau), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Mechanisms controlling maintenance of cohesin dependent loops
Date: 2024-09-10, Time: 11:30:00, Speaker: Frederic Beckouet, Location: Max Perutz Labs SR 1 (6.501), Type: SFB Seminar, Institute: Toulouse Centre de Biologie Intégrative, Host: Franz Klein
Title to be announced
Date: 2024-09-12, Time: 11:00:00, Speaker: Elcin Ünal, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: UC Berkeley, Host: Silvia Ramundo, Fred Berger
Monday Seminar (Internal)
Date: 2024-09-16, Time: 12:30:00, Speaker: WUN Cheuk Ling (Ramundo)andlt;brandgt;MÜLLER Marlene (Rivron)andlt;brandgt;RAUSCHMEIER Rene (Van der Veeken), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-09-19, Time: 11:00:00, Speaker: Noam Stern-Ginossar, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Weizmann Institute of Science, Host: Marco Hein
Monday Seminar (Internal)
Date: 2024-09-23, Time: 12:30:00, Speaker: ESTIVILL I CAPARROS Guillem (Obenauf)andlt;brandgt;VOJTEK Matus (Stark)andlt;brandgt;DA COSTA Barbara (Berger), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-09-26, Time: 11:00:00, Speaker: Maria Mota, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Lisbon, Host: Joao Matos
Title to be announced
Date: 2024-09-27, Time: 11:00:00, Speaker: Deborah Bourcand#x27;his, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: Institut Curie, Host: Julius Brennecke
Monday Seminar (Internal)
Date: 2024-09-30, Time: 12:30:00, Speaker: JÄGER Christina (Van der Veeken)andlt;brandgt;SHUKLA Vikas (Berger)andlt;brandgt;RODRIGUEZ TERRONES Diego (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2024-10-07, Time: 12:30:00, Speaker: KANNO Tatsuo (Berger)andlt;brandgt;SCHIMMER Clara (Ellis)andlt;brandgt;DE SANTIS Martina (Rivron), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-10-10, Time: 11:00:00, Speaker: Cedric Blanpain, Location: , Type: , Institute: Universite Libres Bruxelles, Host: Stephanie Ellis
Monday Seminar (Internal)
Date: 2024-10-14, Time: 12:30:00, Speaker: GAO Peng (Dagdas)andlt;brandgt;RAFANEL Baptiste (Brennecke)andlt;brandgt;FRIDRICH Arie (Berger), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2024-10-17, Time: 11:00:00, Speaker: Ralf Jungmann, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: LMU, MPI, Host: Alex Stark, Francisco Balzarotti
Monday Seminar (Internal)
Date: 2024-10-21, Time: 12:30:00, Speaker: MILOJKOVIC Lidija (Urban)andlt;brandgt;SPENCER Victoria (Dolan)andlt;brandgt;AUGUSTO Pedro (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-10-24, Time: 11:00:00, Speaker: Andrea Ablasser, Location: IMP Lecture Hall, Type: VBC Regular Seminar, Institute: EPFL, Host: Moritz Gaidt
Monday Seminar (Internal)
Date: 2024-10-28, Time: 12:30:00, Speaker: GOMEZ SEGALAS Alba (Balzarotti)andlt;brandgt;KLEINFERCHER Sebastian (Stark)andlt;brandgt;PRADHAN Saurabh (Rivron), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2024-11-04, Time: 12:30:00, Speaker: SCHEPERS Sandra (Knoblich)andlt;brandgt;BUSETTO Virginia (Falk)andlt;brandgt;DMITRIEV Vladimir (Goloborodko), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
VBC PhD Symposium
Date: 2024-11-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2024-11-11, Time: 12:30:00, Speaker: GARCIA GALLARDO Maria (Bücker)andlt;brandgt;HARVEY Zachary (Berger)andlt;brandgt;SAKALLI Enes (Von Haeseler,Menche), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-14, Time: 11:00:00, Speaker: Benoit Bruneau, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Gladstone Institute of Cardiovascular Disease, UCSF, Host: Sasha Menjdan
Monday Seminar (Internal)
Date: 2024-11-18, Time: 12:30:00, Speaker: FESSELET Jeanne (Kovarik)andlt;brandgt;GIAGNISI Eleftheria (Zimmer)andlt;brandgt;SHEN Jingyi (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-18, Time: 11:00:00, Speaker: Lacramioara Bintu, Location: IMBA/GMI Lecture Hall, Type: Impromptu Seminar, Institute: Stanford University, Host: Alex Stark
Title to be announced
Date: 2024-11-21, Time: 11:00:00, Speaker: Martin Jinek, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Zurich, Host: Irma Querques
Monday Seminar (Internal)
Date: 2024-11-25, Time: 12:30:00, Speaker: BOREIKAITE Vytaute (Plaschka)andlt;brandgt;SRINIVASAN Navaneeth (Peters)andlt;brandgt;DODOMANI Ananya (Campbell), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-11-28, Time: 18:00:00, Speaker: David Baker, Location: Zoom, Type: VBC Regular Seminar via Zoom, Institute: UW Dept. of Biochemistry, Host: Alwin Köhler
Monday Seminar (Internal)
Date: 2024-12-02, Time: 12:30:00, Speaker: SOMMER Theresa (Rivron)andlt;brandgt;GORBENKOVA Anastasiia (Leonard)andlt;brandgt;MAIR Zahar (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-12-05, Time: 11:00:00, Speaker: Ian Hickson, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: University of Copenhagen, Host: Joao Matos
Monday Seminar (Internal)
Date: 2024-12-09, Time: 12:30:00, Speaker: BREHM Martin (Falk)andlt;brandgt;PLATZER Sebastian (Hein)andlt;brandgt;HANDLER Dominik (Brennecke), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Title to be announced
Date: 2024-12-12, Time: 11:00:00, Speaker: Stephen West, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: The Francis Crick Institute, Host: Joao Matos
Monday Seminar (Internal)
Date: 2024-12-16, Time: 12:30:00, Speaker: DAHAN Tal (Nordborg)andlt;brandgt;CHUGUNOVA Anastasia (Pauli)andlt;brandgt;VON WIREN Julius (Kovarik), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-01-13, Time: 12:30:00, Speaker: KRASNOVID Filipp (Mari-Ordonez)andlt;brandgt;ROTHE Patricia (Plaschka)andlt;brandgt;KROGULL Daniel (Burga), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-01-20, Time: 12:30:00, Speaker: VICIC Ziga (Jachowicz)andlt;brandgt;GRÜNEWALD Jakob (Obenauf)andlt;brandgt;MANOLOVA Toni (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-01-27, Time: 12:30:00, Speaker: SCARAMUZZA Federico (Tessmar)andlt;brandgt; WALTER Mateusz (Querques)andlt;brandgt;WILLIAMS Thomas (Clausen), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-02-03, Time: 12:30:00, Speaker: CRUZ Joseph (Gerlich)andlt;brandgt;GHEORGHITA Andreea (Clausen)andlt;brandgt;GALUSKA Philipp (Djinovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host:
Monday Seminar (Internal)
Date: 2025-02-10, Time: 12:30:00, Speaker: GRIGOREVA Elizaveta (Nordborg)andlt;brandgt;KOHOUTKOVA Eliska (Clausen)andlt;brandgt;STEINACKER Thomas (Gerlich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-02-17, Time: 12:30:00, Speaker: RAFFL Gerald (Ameres)andlt;brandgt;VULIN Milica (Obenauf)andlt;brandgt;FISCHER Andre (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-02-24, Time: 12:30:00, Speaker: BAYERL Jonas (Zuber)andlt;brandgt;ZABOLOCKI Michael (Knoblich)andlt;brandgt;EDER Stephanie (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Title to be announced
Date: 2025-02-27, Time: 11:00:00, Speaker: Cedric Feschotte, Location: IMBA/GMI Lecture Hall, Type: VBC Regular Seminar, Institute: Cornell University, Host: Joanna Jachowicz
Monday Seminar (Internal)
Date: 2025-03-03, Time: 12:30:00, Speaker: KROETENHEERDT Eva (Leonard)andlt;brandgt;RÖHSNER Josef (Pauli)andlt;brandgt;RIABOV Daria (Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-10, Time: 12:30:00, Speaker: CHO Chung Hyun (Berger)andlt;brandgt;SEIDL Carina (Tanaka)andlt;brandgt;MIGOTTI Mario (Konrat), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-17, Time: 12:30:00, Speaker: CHEN Shenzhi (Stark)andlt;brandgt;BINDL Michael (Leeb)andlt;brandgt;JÄGER Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-24, Time: 12:30:00, Speaker: MAYA Juan (Balzarotti)andlt;brandgt;DOSA Anna (Clausen)andlt;brandgt;KOBER Julia (Ramundo), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-03-31, Time: 12:30:00, Speaker: HOLZER Elisabeth (Martens)andlt;brandgt;THEMANN Jan (Knoblich)andlt;brandgt;GROSS Angelina (Dagdas), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-07, Time: 12:30:00, Speaker: GROH Roan (Dagdas)andlt;brandgt;CHAO Victor (Huis), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-14, Time: 12:30:00, Speaker: OKUN Anastasia (Karagöz)andlt;brandgt;COLLISON Robert (Ramundo)andlt;brandgt;WELZL Paul (Balzarotti/Plaschka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-04-28, Time: 12:30:00, Speaker: SUWITA Johannes (Pauli)andlt;brandgt;GRABARCZYK Daniel (Clausen)andlt;brandgt;PANDA Aswini (Falk), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-05, Time: 12:30:00, Speaker: KIM Olena (Knoblich)andlt;brandgt;JOB Nikhil (Dolan)andlt;brandgt;ADELMANN Leonie (Raible), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Microsymposium on Small RNA Biology
Date: 2025-05-07, Time: 09:00:00, Speaker: , Location: IMP Lecture Hall, Type: Symposium, Institute: None, Host: None
Monday Seminar (Internal)
Date: 2025-05-12, Time: 12:30:00, Speaker: SCIBISZ Grzegorz (Karagöz)andlt;brandgt;VAN GENDEREN Emiel (Rivron)andlt;brandgt;BOZKURT Miray (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-19, Time: 12:30:00, Speaker: POTTENDORFER Elisabeth (Obenauf)andlt;brandgt;WALLNER Eva-Sophie (Dolan)andlt;brandgt;BECKER Moritz (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-05-26, Time: 12:30:00, Speaker: DIMITROVA Polina (Van der Veeken)andlt;brandgt;STRAVS Ana (Knoblich)andlt;brandgt;SCHÖNLEIN Martin (Obenauf), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-02, Time: 12:30:00, Speaker: SABATH Kevin (Plaschka/Stark)andlt;brandgt;MANCHENO JUNCOSA Estela (Mendjan)andlt;brandgt;HORENKAMP Simone (Tanaka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-16, Time: 12:30:00, Speaker: BERGER Sonja (Goloborodko)andlt;brandgt;KOWALD Saskia (Gaidt)andlt;brandgt;KAPRAL Thomas (Zagrovic), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-23, Time: 12:30:00, Speaker: BUCHERON Chloe (Menche)andlt;brandgt;KRUMWIEDE Luisa (Gaidt)andlt;brandgt;PACHANO Tomas (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-06-30, Time: 12:30:00, Speaker: SCHINDLER Lukas (Schlögelhofer)andlt;brandgt;MANDLBURGER Nikolaus (Stark)andlt;brandgt;OTTO Magdalena (Leonard), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-07, Time: 12:30:00, Speaker: TRUS Palina (Peters)andlt;brandgt;KOBAKHIDZE George (Dong)andlt;brandgt;KONGSTED Thea (Dolan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-14, Time: 12:30:00, Speaker: RUSCH Emma (Golobordko)andlt;brandgt;VELIKOV Daniel (Matos), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-21, Time: 12:30:00, Speaker: ANGELOPOULOU Eleni (Ellis)andlt;brandgt;SCHAFFER Petra (Grade)andlt;brandgt;RAMIREZ America (Köhler), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-07-28, Time: 12:30:00, Speaker: DIMITRIADI Anna (Mendjan)andlt;brandgt;LEITNER Moritz (Martinez)andlt;brandgt;RAUH Felix (Stark), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-04, Time: 12:30:00, Speaker: LI Wenxin (Zimmer)andlt;brandgt;FISCHER Felix (Zagrovic)andlt;brandgt;ABESAMIS Kim Ivan (Dong), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-11, Time: 12:30:00, Speaker: KLEIFELD Justus (Urban)andlt;brandgt;MCATEER Tara (Pinheiro)andlt;brandgt;BHATTACHARYA Mrinnanda (Zimmer), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-18, Time: 12:30:00, Speaker: BELL Lillie (Clausen)andlt;brandgt;MIHAILOVIC Milica (Karagöz)andlt;brandgt;GUYNES Keroshini (Jachowicz), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-08-25, Time: 12:30:00, Speaker: BOHL VIALLEFONT Gregoire (Nordborg)andlt;brandgt;MARCHIORI Elisa (Van der Veeken)andlt;brandgt;JAHNEL Stefan (Mendjan), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-01, Time: 12:30:00, Speaker: KIRCHGATTERER Paul (Gaidt)andlt;brandgt;ACHLEITNER Sonja (Martens)andlt;brandgt;KAYA Oguzhan (Knoblich), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-08, Time: 12:30:00, Speaker: HUTH Michelle (Leeb)andlt;brandgt;RADHAKRISHNA PILLAI Balashankar (Brennecke)andlt;brandgt;REN Kaike (Otsuka), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None
Monday Seminar (Internal)
Date: 2025-09-15, Time: 12:30:00, Speaker: GONZALEZ ALVARADO Maria Nazareth (Grade)andlt;brandgt;KASHKO Nataliia (Matos)andlt;brandgt;OBERHUEMER Michael (Leeb), Location: IMP Lecture Hall, Type: Monday Seminar, Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs, Host: None