Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and autophagy.
Picchianti, Lorenzo; Sánchez de Medina Hernández, Víctor; Zhan, Ni; Irwin, Nicholas At; Groh, Roan; Stephani, Madlen; Hornegger, Harald; Beveridge, Rebecca; Sawa-Makarska, Justyna; Lendl, Thomas; Grujic, Nenad; Naumann, Christin; Martens, Sascha; Richards, Thomas A; Clausen, Tim; Ramundo, Silvia; Karagöz, G Elif; Dagdas, Yasin
Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.
Truebestein, Linda; Hornegger, Harald; Anrather, Dorothea; Hartl, Markus; Fleming, Kaelin D; Stariha, Jordan T B; Pardon, Els; Steyaert, Jan; Burke, John E; Leonard, Thomas A
Multifaceted deregulation of gene expression and protein synthesis with age.
Anisimova, Aleksandra S; Meerson, Mark B; Gerashchenko, Maxim V; Kulakovskiy, Ivan V; Dmitriev, Sergey E; Gladyshev, Vadim N
In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay
Karagöz, Elif; Peschek, Jirka; Walter, Peter; Acosta-Alvear, Diego
Recent advances in signal integration mechanisms in the unfolded protein response.
Karagöz, G Elif; Aragón, Tomás; Acosta-Alvear, Diego
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum.
Karagöz, G Elif; Acosta-Alvear, Diego; Walter, Peter
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1.
Acosta-Alvear, Diego; Karagöz, Gülsün Elif; Fröhlich, Florian; Li, Han; Walther, Tobias C; Walter, Peter
An unfolded protein-induced conformational switch activates mammalian IRE1.
Karagöz, G Elif; Acosta-Alvear, Diego; Nguyen, Hieu T; Lee, Crystal P; Chu, Feixia; Walter, Peter
Protein Folding and Chaperones
Sinnige, Tessa; Karagöz, Elif; Rüdiger, Stefan
Hsp90-Tau complex reveals molecular basis for specificity in chaperone action.
Karagöz, G Elif; Duarte, Afonso M S; Akoury, Elias; Ippel, Hans; Biernat, Jacek; Morán Luengo, Tania; Radli, Martina; Didenko, Tatiana; Nordhues, Bryce A; Veprintsev, Dmitry B; Dickey, Chad A; Mandelkow, Eckhard; Zweckstetter, Markus; Boelens, Rolf; Madl, Tobias; Rüdiger, Stefan G D
The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.
Suijkerbuijk, Saskia J E; van Dam, Teunis J P; Karagöz, G Elif; von Castelmur, Eleonore; Hubner, Nina C; Duarte, Afonso M S; Vleugel, Mathijs; Perrakis, Anastassis; Rüdiger, Stefan G D; Snel, Berend; Kops, Geert J P L
Hsp90 structure and function studied by NMR spectroscopy.
Didenko, Tatiana; Duarte, Afonso M S; Karagöz, G Elif; Rüdiger, Stefan G D
Expressed protein ligation for a large dimeric protein.
Karagöz, G Elif; Sinnige, Tessa; Hsieh, Ofey; Rüdiger, Stefan G D
N-terminal domain of human Hsp90 triggers binding to the cochaperone p23.
Karagöz, G Elif; Duarte, Afonso M S; Ippel, Hans; Uetrecht, Charlotte; Sinnige, Tessa; van Rosmalen, Martijn; Hausmann, Jens; Heck, Albert J R; Boelens, Rolf; Rüdiger, Stefan G D
Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy.
Häcker, Irina; Sander, Bjoern; Golas, Monika M; Wolf, Elmar; Karagöz, Elif; Kastner, Berthold; Stark, Holger; Fabrizio, Patrizia; Lührmann, Reinhard
Dissecting the turgor sensing mechanisms in the blast fungus Magnaporthe oryzae
Pikobodies: What does it take to bioengineer NLR immune receptor-nanobody fusions
scRNA and phylogenetics
Gene regulatory mechanisms governing human development, evolution and variation
Regulation of Cerebral Cortex Morphogenesis by Migrating Cells
Phage therapy for treating bacterial infections: a double-edged sword
Suckers and segments of the octopus arm
Using the house mouse radiation to study the rapid evolution of genes and genetic processes
CRISPR jumps ahead: mechanistic insights into CRISPR-associated transposons
SLiMs and SHelMs: Decoding how short linear and helical motifs direct PPP specificity to direct signaling
Title to be announced
Enigmatic evolutionary origin and multipotency of the neural crest cells - major drivers of vertebrate evolution
Visualising mitotic chromosomes and nuclear dynamics by correlative light and electron microscopy
Engineered nanocarriers for imaging of small proteins by CryoEM
Bacterial cell envelope homeostasis at the (post)transcriptional level
Title to be announced
Hydrologic extremes alter mechanisms and pathways of carbon export from mountainous floodplain soils
Dissecting post-transcriptional gene expression regulation in humans and viruses
Polyploidy and rediploidisation in stressful times
Prdm9 control of meiotic synapsis of homologs in intersubspecific hybrids
Title to be announced
RNA virus from museum specimens
Programmed DNA double-strand breaks during meiosis: Mechanism and evolution
Title to be announced