Centrosomes play a pivotal role in animal cell division by nucleating and organizing the microtubules of the mitotic spindle. They are composed of a centriole core and a surrounding pericentriolar material (PCM) matrix. Centrosomes act as mechanical elements that respond to pulling forces exerted by molecular motors on microtubules anchored within the PCM.
The aim of this project is to determine and characterize the molecular elements responsible for conferring mechanical strength to the PCM during cell division in C. elegans embryos.
A Master’s thesis position on an exciting, state-of-the art project in an interactive and international lab environment. The student will be supervised and trained throughout the project but will be expected to work independently. Master students will receive a stipend (similar to the FWF “Forschungsbeihilfe”) of about 470 euro/month.
Feel free to apply directly by sending a CV and motivation letter (max. 500 words) to one the email addresses.
For more details see our lab website, Twitter (@DammermannLab) and recent publications.